Download MendeleyStructural and biophysical studies of TRIM2 and TRIM3
Perez-Borrajero, C., Hennig, J.To be published.
8A38 | pdb_00008a38
RING domain of human TRIM2
- PDB DOI: https://doi.org/10.2210/pdb8A38/pdb
- Classification: ANTIVIRAL PROTEIN
- Organism(s): Homo sapiens
- Expression System: Escherichia coli B
- Mutation(s): No
- Deposited: 2022-06-07 Released: 2023-09-20
- Funding Organization(s): German Research Foundation (DFG), EIPOD fellowship under Marie Sklodowska-Curie Actions COFUND
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.288 (Depositor), 0.290 (DCC)
- R-Value Work: 0.258 (Depositor), 0.260 (DCC)
- R-Value Observed: 0.259 (Depositor)
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Tripartite motif-containing protein 2 | 96 | Homo sapiens | Mutation(s): 0 Gene Names: TRIM2, KIAA0517, RNF86 EC: 2.3.2.27 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9C040 (Homo sapiens) Explore Q9C040 Go to UniProtKB: Q9C040 | |||||
PHAROS: Q9C040 GTEx: ENSG00000109654 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9C040 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ZN (Subject of Investigation/LOI) Query on ZN | D [auth A] E [auth A] F [auth B] G [auth B] H [auth C] | ZINC ION Zn PTFCDOFLOPIGGS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.20 Å
- R-Value Free: 0.288 (Depositor), 0.290 (DCC)
- R-Value Work: 0.258 (Depositor), 0.260 (DCC)
- R-Value Observed: 0.259 (Depositor)
Space Group: P 32 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 48.71 | α = 90 |
| b = 48.71 | β = 90 |
| c = 221.62 | γ = 120 |
| Software Name | Purpose |
|---|---|
| XDS | data scaling |
| XDS | data reduction |
| PHENIX | refinement |
| MxCuBE | data collection |
| PHENIX | phasing |
| Coot | model building |
Entry History & Funding Information
Deposition Data
- Released Date: 2023-09-20 Deposition Author(s): Perez-Borrajero, C., Murciano, B., Hennig, J.
| Funding Organization | Location | Grant Number |
|---|---|---|
| German Research Foundation (DFG) | Germany | HE 7291_1 |
| EIPOD fellowship under Marie Sklodowska-Curie Actions COFUND | Germany | 664726 |
Revision History (Full details and data files)
- Version 1.0: 2023-09-20
Type: Initial release
