Tripartite motif-containing protein 2

UniProtKB accession: Q9C040

Grouped By: Matching UniProtKB accession

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Polymer Entities matching query 443

Go to UniProtKB: Q9C040

UniProtKB description: UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. Plays a role in antiviral immunity and limits New World arenavirus infection independently of its ubiquitin ligase activity (PubMed:24068738).

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