5N8J

CRYSTAL STRUCTURE OF STREPTAVIDIN WITH PEPTIDE D-amino acid containing peptide GyGlanvdessG

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C	SCOP2B Superfamily	Avidin/streptavidin	8040372	3001465	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Avidin/streptavidin	8040372	3001465	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Avidin/streptavidin	8040372	3001465	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Avidin/streptavidin	8040372	3001465	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C	Avidin	e5n8jC1	A: beta barrels	X: Lipocalins/Streptavidin	H: Avidin/Streptavidin (From Topology)	T: Avidin/Streptavidin	F: Avidin	ECOD (1.6)
A	Avidin	e5n8jA1	A: beta barrels	X: Lipocalins/Streptavidin	H: Avidin/Streptavidin (From Topology)	T: Avidin/Streptavidin	F: Avidin	ECOD (1.6)
B	Avidin	e5n8jB1	A: beta barrels	X: Lipocalins/Streptavidin	H: Avidin/Streptavidin (From Topology)	T: Avidin/Streptavidin	F: Avidin	ECOD (1.6)
D	Avidin	e5n8jD1	A: beta barrels	X: Lipocalins/Streptavidin	H: Avidin/Streptavidin (From Topology)	T: Avidin/Streptavidin	F: Avidin	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C	2.40.128.30	Mainly Beta	Beta Barrel	Lipocalin	Avidin-like	CATH (4.3.0)
A	2.40.128.30	Mainly Beta	Beta Barrel	Lipocalin	Avidin-like	CATH (4.3.0)
B	2.40.128.30	Mainly Beta	Beta Barrel	Lipocalin	Avidin-like	CATH (4.3.0)
D	2.40.128.30	Mainly Beta	Beta Barrel	Lipocalin	Avidin-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF01382	Avidin family (Avidin)	Avidin family	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Streptavidin	biotin binding amide binding organic acid binding binding vitamin binding ion binding organic cyclic compound binding anion binding carboxylic acid binding heterocyclic compound binding monocarboxylic acid binding small molecule binding sulfur compound binding	-	cellular anatomical structure extracellular region
E [auth P], F [auth O], G [auth E]	GLY-DTY-GLY-DLE-DAL-DSG-DVA-DAS-DGL-DSN-DSN-GLY	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR017889	Avidin-like, conserved site	Conserved Site
A, B, C, D	IPR036896	Avidin-like superfamily	Homologous Superfamily
A, B, C, D	IPR051764	Avidin/Streptavidin-related	Family
A, B, C, D	IPR005468	Avidin/streptavidin	Family
A, B, C, D	IPR005469	Avidin	Family

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
E [auth P], F [auth O], G [auth E]	DAL	RESID: AA0111 , AA0191 PSI-MOD : meso-lanthionine MOD:00120 , D-alanine (Ala) MOD:00198 , D-alanine (Ser) MOD:00858 , D-alanine MOD:00862
E [auth P], F [auth O], G [auth E]	DAS	RESID: AA0111 , AA0191 , AA0190 PSI-MOD : meso-lanthionine MOD:00120 , D-alanine (Ala) MOD:00198 , D-alanine (Ser) MOD:00858 , D-alanine MOD:00862 , D-aspartic acid (Asp) MOD:01921 , D-aspartic acid (Asn) MOD:01930
E [auth P], F [auth O], G [auth E]	DGL	RESID: AA0111 , AA0191 , AA0190
E [auth P], F [auth O], G [auth E]	DLE	RESID: AA0111 , AA0191 , AA0190 , AA0197 PSI-MOD : meso-lanthionine MOD:00120 , D-alanine (Ala) MOD:00198 , D-alanine (Ser) MOD:00858 , D-alanine MOD:00862 , D-aspartic acid (Asp) MOD:01921 , D-aspartic acid (Asn) MOD:01930 , D-leucine MOD:00204
E [auth P], F [auth O], G [auth E]	DSG	RESID: AA0111 , AA0191 , AA0190 , AA0197 , AA0196 , AA0622 PSI-MOD : meso-lanthionine MOD:00120 , D-alanine (Ala) MOD:00198 , D-alanine (Ser) MOD:00858 , D-alanine MOD:00862 , D-aspartic acid (Asp) MOD:01921 , D-aspartic acid (Asn) MOD:01930 , D-leucine MOD:00204 , D-asparagine MOD:00203 , 2-(L-cystein-S-yl)-D-asparagine MOD:01985
E [auth P], F [auth O], G [auth E]	DSN	RESID: AA0111 , AA0191 , AA0190 , AA0197 , AA0196 , AA0622 , AA0195 , AA0624 PSI-MOD : meso-lanthionine MOD:00120 , D-alanine (Ala) MOD:00198 , D-alanine (Ser) MOD:00858 , D-alanine MOD:00862 , D-aspartic acid (Asp) MOD:01921 , D-aspartic acid (Asn) MOD:01930 , D-leucine MOD:00204 , D-asparagine MOD:00203 , 2-(L-cystein-S-yl)-D-asparagine MOD:01985 , D-serine (Ser) MOD:00202 , D-serine MOD:00891 , D-serine (Cys) MOD:00892 , 2-(L-cystein-S-yl)-D-serine MOD:01987
E [auth P], F [auth O], G [auth E]	DTY	RESID: AA0111 , AA0191 , AA0190 , AA0197 , AA0196 , AA0622 , AA0195 , AA0624
E [auth P], F [auth O], G [auth E]	DVA	RESID: AA0111 , AA0191 , AA0190 , AA0197 , AA0196 , AA0622 , AA0195 , AA0624 , AA0200 PSI-MOD : meso-lanthionine MOD:00120 , D-alanine (Ala) MOD:00198 , D-alanine (Ser) MOD:00858 , D-alanine MOD:00862 , D-aspartic acid (Asp) MOD:01921 , D-aspartic acid (Asn) MOD:01930 , D-leucine MOD:00204 , D-asparagine MOD:00203 , 2-(L-cystein-S-yl)-D-asparagine MOD:01985 , D-serine (Ser) MOD:00202 , D-serine MOD:00891 , D-serine (Cys) MOD:00892 , 2-(L-cystein-S-yl)-D-serine MOD:01987 , D-valine MOD:00705

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.