DSN
D-SERINE
| Created: | 1999-07-08 |
| Last modified: | 2023-11-03 |
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Chemical Details | |
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| Formal Charge | 0 |
| Atom Count | 14 |
| Chiral Atom Count | 1 |
| Bond Count | 13 |
| Aromatic Bond Count | 0 |
Chemical Component Summary | |
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| Name | D-SERINE |
| Systematic Name (OpenEye OEToolkits) | (2R)-2-amino-3-hydroxy-propanoic acid |
| Formula | C3 H7 N O3 |
| Molecular Weight | 105.093 |
| Type | D-PEPTIDE LINKING |
Chemical Descriptors | |||
|---|---|---|---|
| Type | Program | Version | Descriptor |
| SMILES | ACDLabs | 10.04 | O=C(O)C(N)CO |
| SMILES | CACTVS | 3.341 | N[CH](CO)C(O)=O |
| SMILES | OpenEye OEToolkits | 1.5.0 | C(C(C(=O)O)N)O |
| Canonical SMILES | CACTVS | 3.341 | N[C@H](CO)C(O)=O |
| Canonical SMILES | OpenEye OEToolkits | 1.5.0 | C([C@H](C(=O)O)N)O |
| InChI | InChI | 1.03 | InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1 |
| InChIKey | InChI | 1.03 | MTCFGRXMJLQNBG-UWTATZPHSA-N |
Drug Info: DrugBank
| DrugBank ID | DB03929 |
|---|---|
| Name | D-Serine |
| Groups |
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| Description | A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids. [PubChem] |
| Synonyms | D-Serine |
| CAS number | 312-84-5 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | MSTMRLLTLALLFSCSVARAACDPKIVNIGAVLSTRKHEQMFREAVNQAN... | unknown | |
| Glycine receptor subunit alpha-1 | MYSFNTLRLYLWETIVFFSLAASKEAEAARSAPKPMSPSDFLDKLMGRTS... | unknown | |
| Serpin B3 | MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTA... | unknown | |
| Head decoration protein | MVTKTITEQRAEVRIFAGNDPAHTATGSSGISSPTPALTPLMLDEATGKL... | unknown | |
| Monocarboxylate transporter 10 | MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVEL... | unknown | inhibitor |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 6857549, 71077 |
| ChEMBL | CHEMBL285123 |
| ChEBI | CHEBI:16523, CHEBI:35247 |
| CCDC/CSD | ZIXBOA, AYACUZ, NELRAX, DLSERN34, DLSERN12, VOKHEJ, JEJVEA, XATVUK, BUTBOJ, PAZCUO01 |
