DLE

D-LEUCINE

Created: 1999-07-08
Last modified:  2024-09-27

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Chemical Details

Formal Charge0
Atom Count22
Chiral Atom Count1
Bond Count21
Aromatic Bond Count0
2D diagram of DLE
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Chemical Component Summary

NameD-LEUCINE
Systematic Name (OpenEye OEToolkits)(2R)-2-amino-4-methyl-pentanoic acid
FormulaC6 H13 N O2
Molecular Weight131.173
TypeD-PEPTIDE LINKING

Chemical Descriptors

TypeProgram Version Descriptor
SMILESACDLabs10.04O=C(O)C(N)CC(C)C
SMILESCACTVS3.341CC(C)C[CH](N)C(O)=O
SMILESOpenEye OEToolkits1.5.0CC(C)CC(C(=O)O)N
Canonical SMILESCACTVS3.341 CC(C)C[C@@H](N)C(O)=O
Canonical SMILESOpenEye OEToolkits1.5.0 CC(C)C[C@H](C(=O)O)N
InChIInChI1.03 InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m1/s1
InChIKeyInChI1.03 ROHFNLRQFUQHCH-RXMQYKEDSA-N

Drug Info: DrugBank

DrugBank IDDB01746 
NameD-Leucine
Groups experimental
DescriptionAn essential branched-chain amino acid important for hemoglobin formation. [PubChem]
Synonyms
  • D-2-Amino-4-methylvaleric acid
  • D-Leuzin
  • (R)-(−)-leucine
  • (R)-leucine
  • (2R)-2-amino-4-methylpentanoic acid
CAS number328-38-1

Drug Targets

NameTarget SequencePharmacological ActionActions
Monocarboxylate transporter 10MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVEL...unknowninhibitor
Large neutral amino acids transporter small subunit 1MAGAGPKRRALAAPAAEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNI...unknown
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 6950207, 439524
ChEMBL CHEMBL1232258
ChEBI CHEBI:28225, CHEBI:143079
CCDC/CSD CADPEF, GOWCAW, POVYUV, DLLEUC02, URODEL, HAGZUL, PATPUV, FITNIF, GOWBOJ, DLLEUC, DLLEUC03, ZATMUG, ZATJOX, WIPQOE01, ZATNER, SAJYUB, ZATNAN
COD 4501604