Download MendeleyCSNK1G3 bound to SB-223133
Szklarz, M., Elkins, J.M.To be published.
6GRO
Human CSNK1G3 bound to SB-223133
- PDB DOI: https://doi.org/10.2210/pdb6GRO/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2018-06-12 Released: 2018-06-20
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.45 Å
- R-Value Free: 0.167
- R-Value Work: 0.134
- R-Value Observed: 0.135
Starting Model: experimental
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This is version 1.3 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Casein kinase I isoform gamma-3 | 330 | Homo sapiens | Mutation(s): 0 Gene Names: CSNK1G3 EC: 2.7.11.1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9Y6M4 (Homo sapiens) Explore Q9Y6M4 Go to UniProtKB: Q9Y6M4 | |||||
PHAROS: Q9Y6M4 GTEx: ENSG00000151292 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9Y6M4 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| F92 Query on F92 | G [auth A] | 4-[5-(2-azanylpyrimidin-4-yl)-4-(4-fluorophenyl)imidazol-1-yl]cyclohexan-1-ol C19 H20 F N5 O YNEJNUAUXPCFAS-SHTZXODSSA-N |  | ||
| EDO Query on EDO | B [auth A], C [auth A], E [auth A], F [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
| CL Query on CL | D [auth A] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.45 Å
- R-Value Free: 0.167
- R-Value Work: 0.134
- R-Value Observed: 0.135
- Space Group: P 31 2 1
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 56.75 | α = 90 |
| b = 56.75 | β = 90 |
| c = 221.55 | γ = 120 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| MOSFLM | data reduction |
| SCALA | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2018-06-20 Deposition Author(s): Szklarz, M., Vollmar, M., von Delft, F., Bountra, C., Knapp, S., Edwards, A.M., Arrowsmith, C., Elkins, J.M.
Revision History (Full details and data files)
- Version 1.0: 2018-06-20
Type: Initial release - Version 1.1: 2019-02-20
Changes: Data collection, Derived calculations - Version 1.2: 2019-07-10
Changes: Data collection - Version 1.3: 2024-01-17
Changes: Data collection, Database references, Refinement description
