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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Keywords HAS EXACT PHRASE "ANTIBIOTIC INHIBITOR"

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This query matches 16 Structures.

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Structure Determination Methodology

experimental (16)

Scientific Name of Source Organism

	Escherichia coli K-12 (7)
	Klebsiella pneumoniae (3)
	Streptoalloteichus hindustanus (2)
	Escherichia coli str. K-12 substr. MG1655 (1)
	Staphylococcus aureus (1)
	Streptomyces sp. (1)
	Streptomyces verticillus (1)
	Yersinia pestis (1)

Taxonomy

Bacteria (16)

Experimental Method

X-RAY DIFFRACTION (16)

Polymer Entity Type

Protein (16)

Refinement Resolution (Å)

	1.5 - 2.0 (11)
	2.0 - 2.5 (4)
	2.5 - 3.0 (1)

Release Date

	2000 - 2004 (4)
	2005 - 2009 (9)
	2010 - 2014 (1)
	2015 - 2019 (2)

Enzyme Classification Name

	Hydrolases (8)
	Transferases (2)

Membrane Protein Annotation

OPM (1)

Symmetry Type

	Asymmetric (8)
	Cyclic (8)

SCOP Classification

	Alpha and beta proteins (a+b) (12)
	All alpha proteins (7)
	All beta proteins (1)
	Alpha and beta proteins (a/b) (1)
	Multi-domain proteins (alpha and beta) (1)

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1 to 16 of 16 Structures

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1ECS \| pdb_00001ecs	Download File View File

THE 1.7 A CRYSTAL STRUCTURE OF A BLEOMYCIN RESISTANCE DETERMINANT ENCODED ON THE TRANSPOSON TN5

Maruyama, M., Matoba, Y., Kumagai, T., Sugiyama, M.

(2001) J Biological Chem 276: 9992-9999

Released	2001-05-02
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Klebsiella pneumoniae
Macromolecule	BLEOMYCIN RESISTANCE PROTEIN (protein)
Unique Ligands	CA, PG4

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1EWJ \| pdb_00001ewj	Download File View File

CRYSTAL STRUCTURE OF BLEOMYCIN-BINDING PROTEIN COMPLEXED WITH BLEOMYCIN

Maruyama, M., Kumagai, T., Matoba, Y., Hata, Y., Sugiyama, M.

(2001) J Biological Chem 276: 9992-9999

Released	2001-04-26
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Klebsiella pneumoniae
Macromolecule	BLEOMYCIN RESISTANCE DETERMINANT (protein)
Unique Ligands	BLM

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1LRZ \| pdb_00001lrz	Download File View File

x-ray crystal structure of staphylococcus aureus femA

Benson, T., Prince, D., Mutchler, V., Curry, K., Ho, A., Sarver, R., Hagadorn, J., Choi, G., Garlick, R.

(2002) Structure 10: 1107-1115

Released	2002-09-04
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Staphylococcus aureus
Macromolecule	factor essential for expression of methicillin resistance (protein)

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1QTO \| pdb_00001qto	Download File View File

1.5 A CRYSTAL STRUCTURE OF A BLEOMYCIN RESISTANCE DETERMINANT FROM BLEOMYCIN-PRODUCING STREPTOMYCES VERTICILLUS

Kawano, Y., Kumagai, T., Muta, K., Matoba, Y., Davies, J., Sugiyama, M.

(2000) J Mol Biology 295: 915-925

Released	2000-06-28
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Streptomyces verticillus
Macromolecule	BLEOMYCIN-BINDING PROTEIN (protein)

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1XRK \| pdb_00001xrk	Download File View File

Crystal structure of a mutant bleomycin binding protein from Streptoalloteichus hindustanus displaying increased thermostability

Brouns, S.J.J., Wu, H., Akerboom, J., Turnbull, A.P., de Vos, W.M., Van der Oost, J.

(2005) J Biological Chem 280: 11422-11431

Released	2005-01-11
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Streptoalloteichus hindustanus
Macromolecule	Bleomycin resistance protein (protein)
Unique Ligands	BLM, SO4

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2ZHP \| pdb_00002zhp	Download File View File

Crystal structure of bleomycin-binding protein from Streptoalloteichus hindustanus complexed with bleomycin derivative

Okumura, H., Miyazaki, I., Simizu, S., Osada, H.

To be published

Released	2009-02-17
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Streptoalloteichus hindustanus
Macromolecule	Bleomycin resistance protein (protein)
Unique Ligands	BY6, CL, CU

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6GOS \| pdb_00006gos	Download File View File

E. coli Microcin synthetase McbBCD complex with pro-MccB17 bound

Ghilarov, D., Stevenson, C.E.M., Travin, D.Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D.M., Severinov, K.

(2019) Mol Cell 73: 749-762.e5

Released	2019-01-30
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Escherichia coli str. K-12 substr. MG1655
Macromolecule	Bacteriocin microcin B17 (protein) Microcin B17-processing protein McbB (protein) Microcin B17-processing protein McbC (protein) Microcin B17-processing protein McbD (protein)
Unique Ligands	CL, EDO, FMN, GOL, SO4, ZN

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2GYK \| pdb_00002gyk	Download File View File

Crystal structure of the complex of the Colicin E9 DNase domain with a mutant immunity protein, IMME9 (D51A)

Santi, P.S., Kolade, O.O., Kuhlmann, U.C., Hemmings, A.M.

To be published

Released	2007-05-15
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Escherichia coli K-12
Macromolecule	Colicin-E9 (protein) Colicin-E9 immunity protein (protein)
Unique Ligands	PO4, ZN

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2GZE \| pdb_00002gze	Download File View File

Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y55A)

Santi, P.S., Kolade, O.O., Kuhlmann, U.C., Kleanthous, C., Hemmings, A.M.

To be published

Released	2008-03-18
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Escherichia coli K-12
Macromolecule	Colicin-E9 (protein) Colicin-E9 immunity protein (protein)
Unique Ligands	PO4, ZN

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2GZF \| pdb_00002gzf	Download File View File

Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y54F)

Santi, P.S., Kolade, O.O., Kuhlmann, U.C., Kleanthous, C., Hemmings, A.M.

To be published

Released	2007-07-03
Method	X-RAY DIFFRACTION 1.75 Å
Organisms	Escherichia coli K-12
Macromolecule	Colicin-E9 (protein) Colicin-E9 immunity protein (protein)
Unique Ligands	PO4, ZN

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2GZG \| pdb_00002gzg	Download File View File

Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (Y55F)

Santi, P.S., Kolade, O.O., Kuhlmann, U.C., Kleanthous, C., Hemmings, A.M.

To be published

Released	2008-03-18
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Escherichia coli K-12
Macromolecule	Colicin-E9 (protein) Colicin-E9 immunity protein (protein)
Unique Ligands	PO4, ZN

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2GZI \| pdb_00002gzi	Download File View File

Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (V34A)

Santi, P.S., Kolade, O.O., Kuhlmann, U.C., Kleanthous, C., Hemmings, A.M.

To be published

Released	2008-03-18
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Escherichia coli K-12
Macromolecule	Colicin-E9 (protein) Colicin-E9 immunity protein (protein)
Unique Ligands	PO4, ZN

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2GZJ \| pdb_00002gzj	Download File View File

Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (D51A)

Santi, P.S., Kolade, O.O., Kuhlmann, U.C., Kleanthous, C., Hemmings, A.M.

To be published

Released	2008-03-18
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Escherichia coli K-12
Macromolecule	Colicin-E9 (protein) Colicin-E9 immunity protein (protein)
Unique Ligands	PO4, ZN

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3IIQ \| pdb_00003iiq	Download File View File

Crystallographic analysis of bacterial signal peptidase in ternary complex with Arylomycin A2 and a beta-sultam inhibitor

Paetzel, M.

(2009) Biochemistry 48: 8976

Released	2009-09-01
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli K-12 Streptomyces sp.
Macromolecule	ARYLOMYCIN A2 (protein) SIGNAL PEPTIDASE I (protein)
Unique Ligands	CCN, GOL, JZA, M12, TRT

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3TZF \| pdb_00003tzf	Download File View File

Crystal Structure of the Yersinia pestis Dihydropteroate Synthase with Sulfonamide Drug Complex.

Wu, Y.

(2012) Science 335: 1110-1114

Released	2012-03-14
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Yersinia pestis
Macromolecule	7,8-dihydropteroate synthase (protein)
Unique Ligands	08D, HH2, MG

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6PXX \| pdb_00006pxx	Download File View File

Class D beta-lactamase in complex with beta-lactam antibiotic

van den Akker, F., Kumar, V.

(2019) Antibiotics (Basel) 8:

Released	2019-10-09
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Klebsiella pneumoniae
Macromolecule	Beta-lactamase (protein)
Unique Ligands	5R7, CL, EDO, EPE

1 to 16 of 16 Structures

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RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

1ECS | pdb_00001ecs

THE 1.7 A CRYSTAL STRUCTURE OF A BLEOMYCIN RESISTANCE DETERMINANT ENCODED ON THE TRANSPOSON TN5

1EWJ | pdb_00001ewj

CRYSTAL STRUCTURE OF BLEOMYCIN-BINDING PROTEIN COMPLEXED WITH BLEOMYCIN

1LRZ | pdb_00001lrz

x-ray crystal structure of staphylococcus aureus femA

1QTO | pdb_00001qto

1.5 A CRYSTAL STRUCTURE OF A BLEOMYCIN RESISTANCE DETERMINANT FROM BLEOMYCIN-PRODUCING STREPTOMYCES VERTICILLUS

1XRK | pdb_00001xrk

Crystal structure of a mutant bleomycin binding protein from Streptoalloteichus hindustanus displaying increased thermostability

2ZHP | pdb_00002zhp

Crystal structure of bleomycin-binding protein from Streptoalloteichus hindustanus complexed with bleomycin derivative

6GOS | pdb_00006gos

E. coli Microcin synthetase McbBCD complex with pro-MccB17 bound

2GYK | pdb_00002gyk

Crystal structure of the complex of the Colicin E9 DNase domain with a mutant immunity protein, IMME9 (D51A)

2GZE | pdb_00002gze

Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y55A)

2GZF | pdb_00002gzf

Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y54F)

2GZG | pdb_00002gzg

Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (Y55F)

2GZI | pdb_00002gzi

Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (V34A)

2GZJ | pdb_00002gzj

Crystal Structure of the E9 DNase Domain with a Mutant Immunity Protein IM9 (D51A)

3IIQ | pdb_00003iiq

Crystallographic analysis of bacterial signal peptidase in ternary complex with Arylomycin A2 and a beta-sultam inhibitor

3TZF | pdb_00003tzf

Crystal Structure of the Yersinia pestis Dihydropteroate Synthase with Sulfonamide Drug Complex.

6PXX | pdb_00006pxx

Class D beta-lactamase in complex with beta-lactam antibiotic

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1ECS | pdb_00001ecs

1EWJ | pdb_00001ewj

1LRZ | pdb_00001lrz

1QTO | pdb_00001qto

1XRK | pdb_00001xrk

2ZHP | pdb_00002zhp

6GOS | pdb_00006gos

2GYK | pdb_00002gyk

2GZE | pdb_00002gze

2GZF | pdb_00002gzf

2GZG | pdb_00002gzg

2GZI | pdb_00002gzi

2GZJ | pdb_00002gzj

3IIQ | pdb_00003iiq

3TZF | pdb_00003tzf

6PXX | pdb_00006pxx