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233,249 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Enzyme Classification Number = 6.1.1.11

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Search Summary

This query matches 62 Structures.

Refinements

Structure Determination Methodology

experimental (62)

Scientific Name of Source Organism

	Homo sapiens (17)
	Klebsiella pneumoniae (6)
	Thermus thermophilus HB27 (5)
	Candida albicans (4)
	Methanosarcina barkeri str. Fusaro (4)
	Thermus thermophilus (4)
	Thermus thermophilus HB8 (4)
	Arabidopsis thaliana (3)
	Macaca mulatta (3)
	Pseudomonas aeruginosa (3)

More...

Taxonomy

	Eukaryota (36)
	Bacteria (27)
	Archaea (9)

Experimental Method

	X-RAY DIFFRACTION (52)
	ELECTRON MICROSCOPY (10)

Polymer Entity Type

	Protein (62)
	RNA (10)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (7)
	2.0 - 2.5 (22)
	2.5 - 3.0 (17)
	3.0 - 3.5 (8)
	3.5 - 4.0 (3)
	4.0 - 4.5 (4)

Release Date

	1990 - 1994 (4)
	2005 - 2009 (10)
	2010 - 2014 (9)
	2015 - 2019 (15)
	2020 - 2024 (24)

Enzyme Classification Name

	Ligases (62)
	Transferases (6)
	Isomerases (1)

Symmetry Type

	Cyclic (51)
	Asymmetric (13)

SCOP Classification

	All alpha proteins (4)
	Alpha and beta proteins (a+b) (4)

AllSelected

1 to 25 of 62 Structures

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1SER \| pdb_00001ser	Download File View File

THE 2.9 ANGSTROMS CRYSTAL STRUCTURE OF T. THERMOPHILUS SERYL-TRNA SYNTHETASE COMPLEXED WITH TRNA SER

Biou, S., Cusack, V., Yaremchuk, A., Tukalo, M.

(1994) Science 263: 1404-1410

Released	1994-04-30
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Thermus thermophilus
Macromolecule	PROTEIN (SERYL-TRNA SYNTHETASE (E.C.6.1.1.11)) (protein) TRNASER (nucleic acid)

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1SES \| pdb_00001ses	Download File View File

CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE

Cusack, S., Belrhali, H.

(1994) Science 263: 1432-1436

Released	1994-07-31
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Thermus thermophilus
Macromolecule	SERYL-tRNA SYNTHETASE (protein)
Unique Ligands	AHX, AMP

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1SET \| pdb_00001set	Download File View File

CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE

Cusack, S., Belrhali, H.

(1994) Science 263: 1432-1436

Released	1994-07-31
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Thermus thermophilus
Macromolecule	SERYL-tRNA SYNTHETASE (protein)
Unique Ligands	SSA

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1SRY \| pdb_00001sry	Download File View File

REFINED CRYSTAL STRUCTURE OF THE SERYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS AT 2.5 ANGSTROMS RESOLUTION

Fujinaga, M., Berthet-Colominas, C., Cusack, S.

(1993) J Mol Biology 234: 222-233

Released	1994-01-31
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Thermus thermophilus
Macromolecule	SERYL-tRNA SYNTHETASE (protein)

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1WLE \| pdb_00001wle	Download File View File

Crystal Structure of mammalian mitochondrial seryl-tRNA synthetase complexed with seryl-adenylate

Chimnaronk, S., Jeppesen, M.G., Suzuki, T., Nyborg, J., Watanabe, K.

(2005) EMBO J 24: 3369-3379

Released	2005-09-06
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Bos taurus
Macromolecule	Seryl-tRNA synthetase (protein)
Unique Ligands	SRP

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2CIM \| pdb_00002cim	Download File View File

Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase

Bilokapic, S., Maier, T., Ahel, D., Gruic-Sovulj, I., Soll, D., Weygand-Durasevic, I., Ban, N.

(2006) EMBO J 25: 2498

Released	2006-06-26
Method	X-RAY DIFFRACTION 2.51 Å
Organisms	Methanosarcina barkeri str. Fusaro
Macromolecule	SERYL-TRNA SYNTHETASE (protein)
Unique Ligands	CL, PT, ZN

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2CJ9 \| pdb_00002cj9	Download File View File

Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with an analog of seryladenylate

Bilokapic, S., Maier, T., Ahel, D., Gruic-Sovulj, I., Soll, D., Weygand-Durasevic, I., Ban, N.

(2006) EMBO J 25: 2498

Released	2006-06-26
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Methanosarcina barkeri str. Fusaro
Macromolecule	SERYL-TRNA SYNTHETASE (protein)
Unique Ligands	CL, SSA, ZN

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2CJA \| pdb_00002cja	Download File View File

Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with ATP

Bilokapic, S., Maier, T., Ahel, D., Gruic-Sovulj, I., Soll, D., Weygand-Durasevic, I., Ban, N.

(2006) EMBO J 25: 2498

Released	2006-06-26
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Methanosarcina barkeri str. Fusaro
Macromolecule	SERYL-TRNA SYNTHETASE (protein)
Unique Ligands	ATP, CL, MG, ZN

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2CJB \| pdb_00002cjb	Download File View File

Crystal structure of Methanosarcina barkeri seryl-tRNA synthetase complexed with serine

Bilokapic, S., Maier, T., Ahel, D., Gruic-Sovulj, I., Soll, D., Weygand-Durasevic, I., Ban, N.

(2006) EMBO J 25: 2498

Released	2006-06-26
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Methanosarcina barkeri str. Fusaro
Macromolecule	SERYL-TRNA SYNTHETASE (protein)
Unique Ligands	CL, SER, ZN

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2DQ0 \| pdb_00002dq0	Download File View File

Crystal structure of seryl-tRNA synthetase from Pyrococcus horikoshii complexed with a seryl-adenylate analog

Itoh, Y., Sekine, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)

(2008) RNA Biol 5: 169-177

Released	2007-06-05
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Pyrococcus horikoshii OT3
Macromolecule	Seryl-tRNA synthetase (protein)
Unique Ligands	SO4, SSA

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2DQ3 \| pdb_00002dq3	Download File View File

Crystal structure of aq_298

Itoh, Y., Sekine, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)

To be published

Released	2007-06-05
Method	X-RAY DIFFRACTION 3 Å
Organisms	Aquifex aeolicus VF5
Macromolecule	Seryl-tRNA synthetase (protein)
Unique Ligands	SSA

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2ZR2 \| pdb_00002zr2	Download File View File

Crystal structure of seryl-tRNA synthetase from Pyrococcus horikoshii complexed with ATP

Itoh, Y., Sekine, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)

(2008) RNA Biol 5: 169-177

Released	2008-09-09
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Pyrococcus horikoshii OT3
Macromolecule	Seryl-tRNA synthetase (protein)
Unique Ligands	AMP, SO4

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2ZR3 \| pdb_00002zr3	Download File View File

Crystal structure of seryl-tRNA synthetase from Pyrococcus horikoshii

Itoh, Y., Sekine, S., Yokoyama, S., RIKEN Structural Genomics/Proteomics Initiative (RSGI)

(2008) RNA Biol 5: 169-177

Released	2008-09-09
Method	X-RAY DIFFRACTION 3 Å
Organisms	Pyrococcus horikoshii OT3
Macromolecule	Seryl-tRNA synthetase (protein)

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3ERR \| pdb_00003err	Download File View File

Microtubule binding domain from mouse cytoplasmic dynein as a fusion with seryl-tRNA synthetase

Carter, A.P.

(2008) Science 322: 1691-1695

Released	2008-11-25
Method	X-RAY DIFFRACTION 2.27 Å
Organisms	Mus musculus Thermus thermophilus HB27
Macromolecule	fusion protein of microtubule binding domain from mouse cytoplasmic dynein and seryl-tRNA synthetase from Thermus thermophilus (protein)
Unique Ligands	AMP

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3LSQ \| pdb_00003lsq	Download File View File

Trypanosoma brucei seryl-tRNA synthetase

Larson, E.T., Merritt, E.A., Medical Structural Genomics of Pathogenic Protozoa (MSGPP)

To be published

Released	2010-03-02
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Trypanosoma brucei
Macromolecule	Seryl-tRNA synthetase (protein)
Unique Ligands	MLI, NA

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3LSS \| pdb_00003lss	Download File View File

Trypanosoma brucei seryl-tRNA synthetase in complex with ATP

Larson, E.T., Merritt, E.A., Medical Structural Genomics of Pathogenic Protozoa (MSGPP)

To be published

Released	2010-03-02
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Trypanosoma brucei
Macromolecule	Seryl-tRNA synthetase (protein)
Unique Ligands	ATP, MLI, NA

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3QNE \| pdb_00003qne	Download File View File

Candida albicans seryl-tRNA synthetase

Rocha, R., Santos, M.A., Pereira, P.J.B., Macedo-Ribeiro, S.

(2011) Proc Natl Acad Sci U S A 108: 14091-14096

Released	2011-08-03
Method	X-RAY DIFFRACTION 2 Å
Organisms	Candida albicans
Macromolecule	Seryl-tRNA synthetase, cytoplasmic (protein)

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3QO5 \| pdb_00003qo5	Download File View File

Crystal Structure of the seryl-tRNA synthetase from Candida albicans

Rocha, R., Santos, M.A., Pereira, P.J.B., Macedo-Ribeiro, S.

(2011) Proc Natl Acad Sci U S A 108: 14091-14096

Released	2011-08-03
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Candida albicans
Macromolecule	Seryl-tRNA synthetase, cytoplasmic (protein)

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3QO7 \| pdb_00003qo7	Download File View File

Crystal structure of the seryl-tRNA synthetase from Candida albicans

Rocha, R., Santos, M.A., Pereira, P.J.B., Macedo-Ribeiro, S.

(2011) Proc Natl Acad Sci U S A 108: 14091-14096

Released	2011-08-03
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Candida albicans
Macromolecule	Seryl-tRNA synthetase, cytoplasmic (protein)
Unique Ligands	ATP

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3QO8 \| pdb_00003qo8	Download File View File

Crystal Structure of seryl-tRNA synthetase from Candida albicans

Rocha, R., Santos, M.A., Pereira, P.J.B., Macedo-Ribeiro, S.

(2011) Proc Natl Acad Sci U S A 108: 14091-14096

Released	2011-08-03
Method	X-RAY DIFFRACTION 2 Å
Organisms	Candida albicans
Macromolecule	Seryl-tRNA synthetase, cytoplasmic (protein)
Unique Ligands	MG, SSA

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3VBB \| pdb_00003vbb	Download File View File

Crystal Structure of Seryl-tRNA Synthetase from Human at 2.9 angstroms

Xu, X.L., Yang, X.-L.

(2012) Nat Commun 3: 681-681

Released	2012-02-29
Method	X-RAY DIFFRACTION 2.891 Å
Organisms	Homo sapiens
Macromolecule	Seryl-tRNA synthetase, cytoplasmic (protein)
Unique Ligands	MG, PO4

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3W3S \| pdb_00003w3s	Download File View File

Crystal structure of A. aeolicus tRNASec in complex with M. kandleri SerRS

Itoh, Y., Sekine, S., Yokoyama, S.

(2013) Nucleic Acids Res 41: 6729-6738

Released	2013-02-13
Method	X-RAY DIFFRACTION 3.095 Å
Organisms	Aquifex aeolicus VF5 Methanopyrus kandleri AV19
Macromolecule	Type-2 serine--tRNA ligase (protein) selenocysteine tRNA (nucleic acid)
Unique Ligands	PT, SO4, SSA, ZN

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4L87 \| pdb_00004l87	Download File View File

Crystal structure of the human seryl-tRNA synthetase in complex with Ser-SA at 2.9 Angstrom resolution

Xu, X., Yang, X.-L.

(2013) Structure 21: 2078-2086

Released	2013-10-02
Method	X-RAY DIFFRACTION 2.897 Å
Organisms	Homo sapiens
Macromolecule	Serine--tRNA ligase, cytoplasmic (protein)
Unique Ligands	MG, PO4, SSA

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4RQE \| pdb_00004rqe	Download File View File

human Seryl-tRNA synthetase dimer complexed with two molecules of tRNAsec

Xie, W., Wang, C., Guo, Y., Tian, Q., Jia, Q.

(2015) Nucleic Acids Res 43: 10534-10545

Released	2015-11-04
Method	X-RAY DIFFRACTION 4 Å
Organisms	Homo sapiens
Macromolecule	Serine--tRNA ligase, cytoplasmic (protein) selenocysteine tRNA (nucleic acid)
Unique Ligands	ANP, SER

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4RQF \| pdb_00004rqf	Download File View File

human Seryl-tRNA synthetase dimer complexed with one molecule of tRNAsec

Xie, W., Wang, C., Guo, Y., Tian, Q., Jia, Q.

(2015) Nucleic Acids Res 43: 10534-10545

Released	2015-11-04
Method	X-RAY DIFFRACTION 3.503 Å
Organisms	Homo sapiens
Macromolecule	Serine--tRNA ligase, cytoplasmic (protein) selenocysteine tRNA (nucleic acid)
Unique Ligands	ANP, SER

1 to 25 of 62 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1SER | pdb_00001ser

1SES | pdb_00001ses

1SET | pdb_00001set

1SRY | pdb_00001sry

1WLE | pdb_00001wle

2CIM | pdb_00002cim

2CJ9 | pdb_00002cj9

2CJA | pdb_00002cja

2CJB | pdb_00002cjb

2DQ0 | pdb_00002dq0

2DQ3 | pdb_00002dq3

2ZR2 | pdb_00002zr2

2ZR3 | pdb_00002zr3

3ERR | pdb_00003err

3LSQ | pdb_00003lsq

3LSS | pdb_00003lss

3QNE | pdb_00003qne

3QO5 | pdb_00003qo5

3QO7 | pdb_00003qo7

3QO8 | pdb_00003qo8

3VBB | pdb_00003vbb

3W3S | pdb_00003w3s

4L87 | pdb_00004l87

4RQE | pdb_00004rqe

4RQF | pdb_00004rqf