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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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Search Summary

This query matches 697 Structures.

Refinements

Structure Determination Methodology

experimental (697)

Scientific Name of Source Organism

	Homo sapiens (480)
	Saccharomyces cerevisiae (67)
	Mus musculus (33)
	Escherichia coli (26)
	Escherichia coli K-12 (20)
	Rattus norvegicus (16)
	Saccharomyces cerevisiae S288C (16)
	Staphylococcus aureus (13)
	Thermus thermophilus (11)
	Oryctolagus cuniculus (10)

More...

Taxonomy

	Eukaryota (565)
	Bacteria (115)
	Archaea (29)
	other sequences (9)
	Riboviria (8)
	Duplodnaviria (2)
	Monodnaviria (1)

Experimental Method

	X-RAY DIFFRACTION (590)
	ELECTRON MICROSCOPY (92)
	SOLUTION NMR (14)
	NEUTRON DIFFRACTION (1)

Polymer Entity Type

	Protein (697)
	RNA (80)

Refinement Resolution (Å)

	1.0 - 1.5 (58)
	1.5 - 2.0 (210)
	2.0 - 2.5 (176)
	2.5 - 3.0 (112)
	3.0 - 3.5 (63)
	3.5 - 4.0 (22)
	4.0 - 4.5 (18)
	> 4.5 (24)

Release Date

	1990 - 1994 (8)
	1995 - 1999 (14)
	2000 - 2004 (49)
	2005 - 2009 (72)
	2010 - 2014 (137)
	2015 - 2019 (188)
	2020 - 2024 (206)
	2025 - 2029 (23)

Enzyme Classification Name

	Hydrolases (533)
	Transferases (76)
	Isomerases (33)
	Oxidoreductases (5)
	Translocases (3)
	Ligases (3)
	Lyases (4)

Membrane Protein Annotation

	mpstruc (2)
	OPM (2)

Symmetry Type

	Asymmetric (624)
	Cyclic (102)
	Dihedral (21)
	Helical (1)

SCOP Classification

	Alpha and beta proteins (a/b) (406)
	Artifacts (94)
	All beta proteins (92)
	All alpha proteins (58)
	Alpha and beta proteins (a+b) (29)
	Coiled coil proteins (3)
	Small proteins (2)
	Peptides (1)

AllSelected

1 to 25 of 697 Structures

Page 1 of 28

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1AGP \| pdb_00001agp	Download File View File

THREE-DIMENSIONAL STRUCTURES AND PROPERTIES OF A TRANSFORMING AND A NONTRANSFORMING GLY-12 MUTANT OF P21-H-RAS

Franken, S.M., Scheidig, A.J., Wittinghofer, A., Goody, R.S.

(1993) Biochemistry 32: 8411-8420

Released	1994-04-30
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	C-H-RAS P21 PROTEIN (protein)
Unique Ligands	GNP, MG

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1AM4 \| pdb_00001am4	Download File View File

COMPLEX BETWEEN CDC42HS.GMPPNP AND P50 RHOGAP (H. SAPIENS)

Rittinger, K., Walker, P., Gamblin, S.J., Smerdon, S.J.

(1997) Nature 388: 693-697

Released	1998-07-15
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens
Macromolecule	CDC42HS (protein) P50-RHOGAP (protein)
Unique Ligands	GNP, MG

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1B23 \| pdb_00001b23	Download File View File

E. coli cysteinyl-tRNA and T. aquaticus elongation factor EF-TU:GTP ternary complex

Nissen, P., Kjeldgaard, M., Thirup, S., Nyborg, J.

(1999) Structure 7: 143-156

Released	1998-12-07
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Escherichia coli Thermus aquaticus
Macromolecule	ELONGATION FACTOR TU (protein) CYSTEINYL TRNA (nucleic acid)
Unique Ligands	CYS, GNP, MG, SO4

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1CF4 \| pdb_00001cf4	Download File View File

CDC42/ACK GTPASE-BINDING DOMAIN COMPLEX

Mott, H.R., Owen, D., Nietlispach, D., Lowe, P.N., Lim, L., Laue, E.D.

(1999) Nature 399: 384-388

Released	1999-06-18
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	PROTEIN (ACTIVATED P21CDC42HS KINASE) (protein) PROTEIN (CDC42 HOMOLOG) (protein)
Unique Ligands	GNP, MG

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1CIP \| pdb_00001cip	Download File View File

GI-ALPHA-1 SUBUNIT OF GUANINE NUCLEOTIDE-BINDING PROTEIN COMPLEXED WITH A GTP ANALOGUE

Coleman, D., Sprang, S.

(1999) J Biological Chem 274: 16669-16672

Released	1999-04-09
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Rattus norvegicus
Macromolecule	PROTEIN (GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-1 SUBUNIT) (protein)
Unique Ligands	GNP, MG

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1CTQ \| pdb_00001ctq	Download File View File

STRUCTURE OF P21RAS IN COMPLEX WITH GPPNHP AT 100 K

Scheidig, A., Burmester, C., Goody, R.S.

(1999) Structure 7: 1311-1324

Released	1999-11-15
Method	X-RAY DIFFRACTION 1.26 Å
Organisms	Homo sapiens
Macromolecule	PROTEIN (TRANSFORMING PROTEIN P21/H-RAS-1) (protein)
Unique Ligands	GNP, MG

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1DAY \| pdb_00001day	Download File View File

CRYSTAL STRUCTURE OF A BINARY COMPLEX OF PROTEIN KINASE CK2 (ALPHA-SUBUNIT) AND MG-GMPPNP

Niefind, K., Puetter, M., Guerra, B., Issinger, O.G., Schomburg, D.

(1999) Nat Struct Biol 6: 1100-1103

Released	2000-05-03
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Zea mays
Macromolecule	PROTEIN KINASE CK2 (protein)
Unique Ligands	GNP, MG

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1E0A \| pdb_00001e0a	Download File View File

Cdc42 complexed with the GTPase binding domain of p21 activated kinase

Morreale, A., Venkatesan, M., Mott, H.R., Owen, D., Nietlispach, D., Lowe, P.N., Laue, E.D.

(2000) Nat Struct Biol 7: 384

Released	2000-04-18
Method	SOLUTION NMR
Organisms	Homo sapiens Rattus norvegicus
Macromolecule	Cell division control protein 42 homolog (protein) Serine/threonine-protein kinase PAK 1 (protein)
Unique Ligands	GNP, MG

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1EFT \| pdb_00001eft	Download File View File

THE CRYSTAL STRUCTURE OF ELONGATION FACTOR EF-TU FROM THERMUS AQUATICUS IN THE GTP CONFORMATION

Kjeldgaard, M., Nissen, P., Thirup, S., Nyborg, J.

(1993) Structure 1: 35-50

Released	1994-08-31
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Thermus aquaticus
Macromolecule	ELONGATION FACTOR TU (protein)
Unique Ligands	GNP, MG

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1EK0 \| pdb_00001ek0	Download File View File

GPPNHP-BOUND YPT51 AT 1.48 A RESOLUTION

Esters, H., Scheidig, A.J.

(2000) J Mol Biology 298: 111-121

Released	2000-04-17
Method	X-RAY DIFFRACTION 1.48 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	PROTEIN (GTP-BINDING PROTEIN YPT51) (protein)
Unique Ligands	GDP, GNP, MG, NI

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1EXM \| pdb_00001exm	Download File View File

CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS ELONGATION FACTOR TU (EF-TU) IN COMPLEX WITH THE GTP ANALOGUE GPPNHP.

Hogg, T., Mesters, J.R., Hilgenfeld, R.

(2000) The Ribosome: Structure, Function, Antibiotics, And Cellular Interactions 28: 347-357

Released	2000-06-07
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Thermus thermophilus
Macromolecule	ELONGATION FACTOR TU (EF-TU) (protein)
Unique Ligands	GNP, MG

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1F5N \| pdb_00001f5n	Download File View File

HUMAN GUANYLATE BINDING PROTEIN-1 IN COMPLEX WITH THE GTP ANALOGUE, GMPPNP.

Prakash, B., Renault, L., Praefcke, G.J.K., Herrmann, C., Wittinghofer, A.

(2000) EMBO J 19: 4555-4564

Released	2000-09-27
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	INTERFERON-INDUCED GUANYLATE-BINDING PROTEIN 1 (protein)
Unique Ligands	GNP, MG

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1G17 \| pdb_00001g17	Download File View File

CRYSTAL STRUCTURE OF SEC4-GUANOSINE-5'-(BETA,GAMMA)-IMIDOTRIPHOSPHATE

Stroupe, C., Brunger, A.T.

(2000) J Mol Biology 304: 585-598

Released	2000-12-11
Method	X-RAY DIFFRACTION 2 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	RAS-RELATED PROTEIN SEC4 (protein)
Unique Ligands	GNP, MG

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1G7T \| pdb_00001g7t	Download File View File

X-RAY STRUCTURE OF TRANSLATION INITIATION FACTOR IF2/EIF5B COMPLEXED WITH GDPNP

Roll-Mecak, A., Cao, C., Dever, T.E., Burley, S.K.

(2000) Cell 103: 781-792

Released	2000-12-01
Method	X-RAY DIFFRACTION 2 Å
Organisms	Methanothermobacter thermautotrophicus
Macromolecule	TRANSLATION INITIATION FACTOR IF2/EIF5B (protein)
Unique Ligands	GNP, MG

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1GL6 \| pdb_00001gl6	Download File View File

Plasmid coupling protein TrwB in complex with the non-hydrolysable GTP analogue GDPNP

Gomis-Ruth, F.X., Moncalian, G., De La cruz, F., Coll, M.

(2001) Nature 409: 637

Released	2002-05-16
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Escherichia coli
Macromolecule	ATPASE (protein)
Unique Ligands	CL, EPE, GNP

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1GUA \| pdb_00001gua	Download File View File

HUMAN RAP1A, RESIDUES 1-167, DOUBLE MUTANT (E30D,K31E) COMPLEXED WITH GPPNHP AND THE RAS-BINDING-DOMAIN OF HUMAN C-RAF1, RESIDUES 51-131

Nassar, N., Wittinghofer, A.

(1996) Nat Struct Biol 3: 723-729

Released	1997-01-11
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	C-RAF1 (protein) RAP1A (protein)
Unique Ligands	CA, GNP, MG

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1HE8 \| pdb_00001he8	Download File View File

Ras G12V - PI 3-kinase gamma complex

Pacold, M.E., Suire, S., Perisic, O., Lara-Gonzalez, S., Davis, C.T., Hawkins, P.T., Walker, E.H., Stephens, L., Eccleston, J.F., Williams, R.L.

(2000) Cell 103: 931

Released	2001-01-08
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens
Macromolecule	PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT, GAMMA ISOFORM (protein) TRANSFORMING PROTEIN P21/H-RAS-1 (protein)
Unique Ligands	GNP, MG

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1HOO \| pdb_00001hoo	Download File View File

STRUCTURE OF GUANINE NUCLEOTIDE (GPPCP) COMPLEX OF ADENYLOSUCCINATE SYNTHETASE FROM E. COLI AT PH 6.5 AND 25 DEGREES CELSIUS

Poland, B.W., Hou, Z., Bruns, C., Fromm, H.J., Honzatko, R.B.

(1996) J Biological Chem 271: 15407-15413

Released	1997-02-12
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Escherichia coli
Macromolecule	ADENYLOSUCCINATE SYNTHETASE (protein)
Unique Ligands	GNH, GNP

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1HUQ \| pdb_00001huq	Download File View File

1.8A CRYSTAL STRUCTURE OF THE MONOMERIC GTPASE RAB5C (MOUSE)

Merithew, E., Hatherly, S., Dumas, J.J., Lawe, D.C., Heller-Harrison, R., Lambright, D.G.

(2001) J Biological Chem 276: 13982-13988

Released	2001-02-07
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Mus musculus
Macromolecule	RAB5C (protein)
Unique Ligands	GNP, MG

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1I4T \| pdb_00001i4t	Download File View File

CRYSTAL STRUCTURE ANALYSIS OF RAC1-GMPPNP IN COMPLEX WITH ARFAPTIN

Tarricone, C., Xiao, B., Justin, N., Gamblin, S.J., Smerdon, S.J.

(2001) Nature 411: 215-219

Released	2001-05-16
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	ARFAPTIN 2 (protein) RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 1 (protein)
Unique Ligands	GNP, MG

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1IAQ \| pdb_00001iaq	Download File View File

C-H-RAS P21 PROTEIN MUTANT WITH THR 35 REPLACED BY SER (T35S) COMPLEXED WITH GUANOSINE-5'-[B,G-IMIDO] TRIPHOSPHATE

Spoerner, M., Herrmann, C., Vetter, I.R., Kalbitzer, H.R., Wittinghofer, A.

(2001) Proc Natl Acad Sci U S A 98: 4944-4949

Released	2001-06-06
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	TRANSFORMING PROTEIN P21/H-RAS-1 (protein)
Unique Ligands	GNP, MG

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1IBR \| pdb_00001ibr	Download File View File

COMPLEX OF RAN WITH IMPORTIN BETA

Vetter, I.R., Arndt, A., Kutay, U., Goerlich, D., Wittinghofer, A.

(1999) Cell 97: 635-646

Released	1999-06-03
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	GTP-binding nuclear protein RAN (protein) Importin beta-1 subunit (protein)
Unique Ligands	GNP, MG

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1JPJ \| pdb_00001jpj	Download File View File

GMPPNP Complex of SRP GTPase NG Domain

Padmanabhan, S., Freymann, D.M.

(2001) Structure 9: 859-867

Released	2002-02-02
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Thermus aquaticus
Macromolecule	SIGNAL RECOGNITION PARTICLE PROTEIN (protein)
Unique Ligands	GNP

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1JPN \| pdb_00001jpn	Download File View File

GMPPNP Complex of SRP GTPase NG Domain

Padmanabhan, S., Freymann, D.M.

(2001) Structure 9: 859-867

Released	2002-02-02
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Thermus aquaticus
Macromolecule	SIGNAL RECOGNITION PARTICLE PROTEIN (protein)
Unique Ligands	ACY, CA, GNP

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1K5D \| pdb_00001k5d	Download File View File

Crystal structure of Ran-GPPNHP-RanBP1-RanGAP complex

Seewald, M.J., Koerner, C., Wittinghofer, A., Vetter, I.R.

(2002) Nature 415: 662-666

Released	2002-02-13
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens Schizosaccharomyces pombe
Macromolecule	GTP-binding nuclear protein RAN (protein) Ran GTPase activating protein 1 (protein) Ran-specific GTPase-activating protein (protein)
Unique Ligands	GNP, MG

1 to 25 of 697 Structures

Page 1 of 28

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1AGP | pdb_00001agp

1AM4 | pdb_00001am4

1B23 | pdb_00001b23

1CF4 | pdb_00001cf4

1CIP | pdb_00001cip

1CTQ | pdb_00001ctq

1DAY | pdb_00001day

1E0A | pdb_00001e0a

1EFT | pdb_00001eft

1EK0 | pdb_00001ek0

1EXM | pdb_00001exm

1F5N | pdb_00001f5n

1G17 | pdb_00001g17

1G7T | pdb_00001g7t

1GL6 | pdb_00001gl6

1GUA | pdb_00001gua

1HE8 | pdb_00001he8

1HOO | pdb_00001hoo

1HUQ | pdb_00001huq

1I4T | pdb_00001i4t

1IAQ | pdb_00001iaq

1IBR | pdb_00001ibr

1JPJ | pdb_00001jpj

1JPN | pdb_00001jpn

1K5D | pdb_00001k5d