RCSB PDB: Search

2A98 \| pdb_00002a98	Download File View File

Crystal structure of the catalytic domain of human inositol 1,4,5-trisphosphate 3-kinase C

Hallberg, B.M., Ogg, D., Ehn, M., Graslund, S., Hammarstrom, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Persson, C., Sagemark, J., Schuler, H., Stenmark, P., Thorsell, A.-G., Arrowsmith, C., Edwards, A., Sundstrom, M., Weigelt, J., Structural Genomics Consortium (SGC)

To be published

Released	2005-07-19
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Inositol 1,4,5-trisphosphate 3-kinase C (protein)
Unique Ligands	I3P

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2B0R \| pdb_00002b0r	Download File View File

Crystal Structure of Cyclase-Associated Protein from Cryptosporidium parvum

Tempel, W., Dong, A., Zhao, Y., Lew, J., Kozieradzki, I., Alam, Z., Melone, M., Wasney, G., Vedadi, M., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Hui, R., Bochkarev, A., Artz, J., Structural Genomics Consortium (SGC)

(2010) J Biological Chem 151: 100-110

Released	2005-09-27
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Cryptosporidium parvum
Macromolecule	possible adenyl cyclase-associated protein (protein)
Unique Ligands	UNX

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2BW0 \| pdb_00002bw0	Download File View File

Crystal Structure of the hydrolase domain of Human 10-Formyltetrahydrofolate 2 dehydrogenase

Ogg, D.J., Stenmark, P., Arrowsmith, C., Edwards, A., Ehn, M., Graslund, S., Hammarstrom, M., Hallberg, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A., Dobritzsch, D., Weigelt, J.

(2006) Acta Crystallogr D Biol Crystallogr 62: 1294

Released	2005-07-08
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE (protein)
Unique Ligands	SO4

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2BZN \| pdb_00002bzn	Download File View File

Crystal structure of human guanosine monophosphate reductase 2 GMPR2 in complex with IMP

Stenmark, P., Kursula, P., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Graslund, S., Hammarstrom, M., Hallberg, B.M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Ogg, D., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A., Weigelt, J.

(2011) Nat Chem Biol 7: 950

Released	2005-09-02
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Homo sapiens
Macromolecule	GMP REDUCTASE 2 (protein)
Unique Ligands	IMP

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2C4K \| pdb_00002c4k	Download File View File

Crystal structure of human phosphoribosylpyrophosphate synthetase- associated protein 39 (PAP39)

Kursula, P., Stenmark, P., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Flodin, S., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Kotenyova, T., Nilsson-Ehle, P., Ogg, D., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Nordlund, P.

To be published

Released	2005-10-24
Method	X-RAY DIFFRACTION 2.65 Å
Organisms	Homo sapiens
Macromolecule	PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE-ASSOCIATED PROTEIN 1 (protein)
Unique Ligands	SO4, TAM

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2C6Q \| pdb_00002c6q	Download File View File

Crystal structure of human guanosine monophosphate reductase 2 GMPR2 in complex with IMP and NADPH

Kursula, P., Stenmark, P., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Graslund, S., Hammarstrom, M., Hallberg, B.M., Kotenyova, T., Nilsson-Ehle, P., Ogg, D., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A., Weigelt, J., Nordlund, P.

(2011) Nat Chem Biol 7: 950

Released	2005-11-30
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	GMP REDUCTASE 2 (protein)
Unique Ligands	IMP, NDP

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2CAR \| pdb_00002car	Download File View File

Crystal Structure Of Human Inosine Triphosphatase

Stenmark, P., Kursula, P., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Hogbom, M., Holmberg Schiavone, L., Kotenyova, T., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Nordlund, P.

(2007) J Biological Chem 282: 3182

Released	2006-01-04
Method	X-RAY DIFFRACTION 1.09 Å
Organisms	Homo sapiens
Macromolecule	INOSINE TRIPHOSPHATE PYROPHOSPHATASE (protein)

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2CFI \| pdb_00002cfi	Download File View File

The hydrolase domain of human 10-FTHFD in complex with 6- formyltetrahydropterin

Kursula, P., Stenmark, P., Arrowsmith, C., Edwards, A., Ehn, M., Graslund, S., Hammarstrom, M., Hallberg, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Ogg, D.J., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A., Weigelt, J.

(2006) Acta Crystallogr D Biol Crystallogr 62: 1294

Released	2006-03-14
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens
Macromolecule	10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE (protein)
Unique Ligands	SO4, ZZZ

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2CL3 \| pdb_00002cl3	Download File View File

Crystal structure of human Cleavage and Polyadenylation Specificity Factor 5 (CPSF5)

Stenmark, P., Hogbom, M., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Kotenyova, T., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.

(2008) Proteins 73: 1047

Released	2006-05-04
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 5 (protein)

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2G9N \| pdb_00002g9n	Download File View File

Structure of the DEAD domain of Human eukaryotic initiation factor 4A, eIF4A

Hogbom, M., Ogg, D., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Uppenberg, J., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2010) PLoS One 5: 12791-12791

Released	2006-03-14
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Homo sapiens
Macromolecule	Eukaryotic initiation factor 4A-I (protein)

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2J4E \| pdb_00002j4e	Download File View File

THE ITP COMPLEX OF HUMAN INOSINE TRIPHOSPHATASE

Stenmark, P., Kursula, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmbergschiavone, L., Hogbom, M., Kotenyova, T., Landry, R., Loppnau, P., Magnusdottir, A., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Schuler, H., Van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.

(2007) J Biological Chem 282: 3182

Released	2006-09-20
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	INOSINE TRIPHOSPHATE PYROPHOSPHATASE (protein)
Unique Ligands	IMP, ITT, MG, POP

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2J8Q \| pdb_00002j8q	Download File View File

Crystal structure of human cleavage and polyadenylation specificity factor 5 (CPSF5) in complex with a sulphate ion.

Moche, M., Stenmark, P., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg, S.L., Hogbom, M., Johansson, I., Karlberg, T., Kosinska, U., Kotenyova, T., Magnusdottir, A., Nilsson, M.E., Nilsson-Ehle, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Upsten, M., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Welin, M., Nordlund, P.

(2008) Proteins 73: 1047

Released	2006-11-13
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 5 (protein)
Unique Ligands	SO4

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2JJZ \| pdb_00002jjz	Download File View File

Crystal Structure of Human Iba2, orthorhombic crystal form

Schulze, J.O., Quedenau, C., Roske, Y., Turnbull, A., Mueller, U., Heinemann, U., Buessow, K.

(2008) FEBS J 275: 4627

Released	2009-07-14
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Homo sapiens
Macromolecule	IONIZED CALCIUM-BINDING ADAPTER MOLECULE 2 (protein)
Unique Ligands	ACT, CL, NA, ZN

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2JKG \| pdb_00002jkg	Download File View File

Plasmodium falciparum profilin

Kursula, I., Kursula, P., Ganter, M., Panjikar, S., Matuschewski, K., Schueler, H.

(2008) Structure 16: 1638

Released	2008-09-23
Method	X-RAY DIFFRACTION 1.89 Å
Organisms	Plasmodium falciparum synthetic construct
Macromolecule	OCTAPROLINE PEPTIDE (protein) PROFILIN (protein)
Unique Ligands	MG

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2P6N \| pdb_00002p6n	Download File View File

Human DEAD-box RNA helicase DDX41, helicase domain

Karlberg, T., Ogg, D., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Johansson, I., Kotenyova, T., Lehtio, L., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2010) PLoS One 5: 12791-12791

Released	2007-04-03
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	ATP-dependent RNA helicase DDX41 (protein)

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2PL3 \| pdb_00002pl3	Download File View File

Human DEAD-box RNA helicase DDX10, DEAD domain in complex with ADP

Karlberg, T., Lehtio, L., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Johansson, I., Kallas, A., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2010) PLoS One 5: 12791-12791

Released	2007-05-01
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Homo sapiens
Macromolecule	Probable ATP-dependent RNA helicase DDX10 (protein)
Unique Ligands	ADP, EOH, MG

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2PQF \| pdb_00002pqf	Download File View File

Human Poly(ADP-Ribose) Polymerase 12, Catalytic fragment in complex with an inhibitor 3-Aminobenzoic acid

Karlberg, T., Lehtio, L., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hogbom, M., Johansson, I., Kallas, A., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2015) J Biological Chem 290: 7336-7344

Released	2007-05-15
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens
Macromolecule	Poly [ADP-ribose] polymerase 12 (protein)
Unique Ligands	CIT, GAB

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2PSO \| pdb_00002pso	Download File View File

Human StarD13 (DLC2) lipid transfer and protein localization domain

Lehtio, L., Busam, R., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Ogg, D., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van den Berg, S., Weigelt, J., Welin, M., Persson, C., Structural Genomics Consortium (SGC)

(2011) PLoS One 6: e19521-e19521

Released	2007-05-15
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	StAR-related lipid transfer protein 13 (protein)

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2QZ4 \| pdb_00002qz4	Download File View File

Human paraplegin, AAA domain in complex with ADP

Karlberg, T., Lehtio, L., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Herman, M.D., Johansson, I., Kallas, A., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Persson, J., Sagemark, C., Sundstrom, M., Thorsell, A.G., Tresauges, L., Van Den Berg, S., Weigelt, J., Welin, M., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2009) PLoS One 4: e6975-e6975

Released	2007-09-11
Method	X-RAY DIFFRACTION 2.22 Å
Organisms	Homo sapiens
Macromolecule	Paraplegin (protein)
Unique Ligands	ADP

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2R55 \| pdb_00002r55	Download File View File

Human StAR-related lipid transfer protein 5

Lehtio, L., Busam, R.D., Arrowsmith, C.H., Berglund, H., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Herman, M.D., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Moche, M., Nordlund, P., Nyman, T., Sagemark, J., Sundstrom, M., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Persson, C., Structural Genomics Consortium (SGC)

(2011) PLoS One 6: e19521-e19521

Released	2007-09-18
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	StAR-related lipid transfer protein 5 (protein)

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2RB4 \| pdb_00002rb4	Download File View File

Crystal structure of the Helicase domain of human DDX25 RNA helicase

Lehtio, L., Hogbom, M., Uppenberg, J., Arrowsmith, C.H., Berglund, H., Edwards, A.M., Ehn, M., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Kotenyova, T., Nilsson-Ehle, P., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2010) PLoS One 5: 12791-12791

Released	2007-10-02
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	ATP-dependent RNA helicase DDX25 (protein)
Unique Ligands	CL, SO4, ZN

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2VO1 \| pdb_00002vo1	Download File View File

CRYSTAL STRUCTURE OF THE SYNTHETASE DOMAIN OF HUMAN CTP SYNTHETASE

Stenmark, P., Kursula, P., Arrowsmith, C., Berglund, H., Edwards, A., Ehn, M., Flodin, S., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Kotenyoa, T., Moche, M., Nilsson-Ehle, P., Ogg, D., Persson, C., Sagemark, J., Schuler, H., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Nordlund, P.

(2006) Acta Crystallogr Sect F Struct Biol Cryst Commun 62: 613

Released	2008-03-11
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	CTP SYNTHASE 1 (protein)
Unique Ligands	SO4

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2VTG \| pdb_00002vtg	Download File View File

Crystal Structure of Human Iba2, trigonal crystal form

Schulze, J.O., Quedenau, C., Roske, Y., Turnbull, A., Mueller, U., Heinemann, U., Buessow, K.

(2008) FEBS J 275: 4627

Released	2009-07-14
Method	X-RAY DIFFRACTION 2.45 Å
Organisms	Homo sapiens
Macromolecule	IONIZED CALCIUM-BINDING ADAPTER MOLECULE 2 (protein)
Unique Ligands	ACT, ZN