TAM

TRIS(HYDROXYETHYL)AMINOMETHANE

Created:	1999-07-08
Last modified:	2011-06-04

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128 entries where TAM is found as a standalone ligand1 entries where TAM is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	28
Chiral Atom Count	0
Bond Count	27
Aromatic Bond Count	0

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Chemical Component Summary
Name	TRIS(HYDROXYETHYL)AMINOMETHANE
Systematic Name (OpenEye OEToolkits)	3-amino-3-(2-hydroxyethyl)pentane-1,5-diol
Formula	C₇ H₁₇ N O₃
Molecular Weight	163.215
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	OCCC(N)(CCO)CCO
SMILES	CACTVS	3.341	NC(CCO)(CCO)CCO
SMILES	OpenEye OEToolkits	1.5.0	C(CO)C(CCO)(CCO)N
Canonical SMILES	CACTVS	3.341	NC(CCO)(CCO)CCO
Canonical SMILES	OpenEye OEToolkits	1.5.0	C(CO)C(CCO)(CCO)N
InChI	InChI	1.03	InChI=1S/C7H17NO3/c8-7(1-4-9,2-5-10)3-6-11/h9-11H,1-6,8H2
InChIKey	InChI	1.03	GKODZWOPPOTFGA-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank ID	DB04237
Name	Tris(Hydroxyethyl)Aminomethane
Groups	experimental
Synonyms	Tris(Hydroxyethyl)Aminomethane

Drug Targets

Name	Target Sequence	Pharmacological Action
Alpha-amylase 1	MKLFWLLFTIGFCWAQYSSNTQQGRTSIVHLFEWRWVDIALECERYLAPK...	unknown
Chlorocatechol 1,2-dioxygenase	MANTRVIELFDEFTDLIRDFIVRHEITTPEYETIMQYMISVGEAGEWPLW...	unknown
Alpha-lytic protease	MYVSNHRSRRVARVSVSCLVAALAAMSCGAALAADQVDPQLKFAMQRDLG...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682