RCSB PDB: Search

2LV5 \| pdb_00002lv5	Download File View File

NMR solution structure of PA1075 from Pseudomonas Aeruginosa

Andresen, C., Anandapadamanaban, M., Schneider, G., Schnell, R., Sunnerhagen, M.

To be published

Released	2013-07-03
Method	SOLUTION NMR
Organisms	Pseudomonas aeruginosa PAO1
Macromolecule	Uncharacterized protein (protein)

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4B0A \| pdb_00004b0a	Download File View File

The high-resolution structure of yTBP-yTAF1 identifies conserved and competing interaction surfaces in transcriptional activation

Anandapadamanaban, M., Andresen, C., Siponen, M., Kokubo, T., Ikura, M., Moche, M., Sunnerhagen, M.

(2013) Nat Struct Mol Biol 20: 1008

Released	2013-07-03
Method	X-RAY DIFFRACTION 1.97 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1, LINKER, TATA-BOX-BINDING PROTEIN (protein)
Unique Ligands	CA, CL, GOL

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4MEW \| pdb_00004mew	Download File View File

Structure of the core fragment of human PR70

Dovega, R.B., Quistgaard, E.M., Tsutakawa, S., Anandapadamanaban, M., Low, C., Nordlund, P.

(2014) PLoS One 9: e101846-e101846

Released	2014-08-13
Method	X-RAY DIFFRACTION 1.993 Å
Organisms	Homo sapiens
Macromolecule	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta (protein)
Unique Ligands	CA, GOL

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4ZZL \| pdb_00004zzl	Download File View File

MexR R21W derepressor mutant causing multidrug resistance in P. aeruginosa by mexAB-oprM efflux pump expression

Anandapadamanaban, M., Pilstal, R., Ziauddin, J.M.E., Moche, M., Wallner, B., Sunnerhagen, M.

(2016) Structure 24: 1311

Released	2016-07-27
Method	X-RAY DIFFRACTION 2.19 Å
Organisms	Pseudomonas aeruginosa
Macromolecule	MULTIDRUG RESISTANCE OPERON REPRESSOR (protein)
Unique Ligands	GOL

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5JPX \| pdb_00005jpx	Download File View File

Solution structure of the TRIM21 B-box2 (B2)

Wallenhammar, A., Anandapadamanaban, M., Sunnerhagen, M.

(2017) PLoS One 12: e0181551-e0181551

Released	2017-08-09
Method	SOLUTION NMR
Organisms	Homo sapiens
Macromolecule	E3 ubiquitin-protein ligase TRIM21 (protein)
Unique Ligands	ZN

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5LBN \| pdb_00005lbn	Download File View File

High-resolution crystal structure of the UBC core domain of UBE2E1/UbcH6

Anandapadamanaban, M., Moche, M., Sunnerhagen, M.

To be published

Released	2018-02-14
Method	X-RAY DIFFRACTION 1.42 Å
Organisms	Homo sapiens
Macromolecule	Ubiquitin-conjugating enzyme E2 E1 (protein)
Unique Ligands	GOL

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6FGA \| pdb_00006fga	Download File View File

Crystal structure of TRIM21 E3 ligase, RING domain in complex with its cognate E2 conjugating enzyme UBE2E1

Anandapadamanaban, M., Moche, M., Sunnerhagen, M.

(2019) J Biological Chem 294: 11404-11419

Released	2019-06-12
Method	X-RAY DIFFRACTION 2.82 Å
Organisms	Homo sapiens
Macromolecule	E3 ubiquitin-protein ligase TRIM21 (protein) Ubiquitin-conjugating enzyme E2 E1 (protein)
Unique Ligands	GOL, ZN

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6S6A \| pdb_00006s6a	Download File View File

Crystal structure of RagA-Q66L/RagC-T90N GTPase heterodimer complex

Anandapadamanaban, M., Masson, G.R., Perisic, O., Kaufman, J., Williams, R.L.

(2019) Science 366: 203-210

Released	2019-10-16
Method	X-RAY DIFFRACTION 2.63 Å
Organisms	Homo sapiens
Macromolecule	Ras-related GTP-binding protein A (protein) Ras-related GTP-binding protein C (protein)
Unique Ligands	9JE, GDP, GTP, MG

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6S6D \| pdb_00006s6d	Download File View File

Crystal structure of RagA-Q66L-GTP/RagC-S75N-GDP GTPase heterodimer complex

Anandapadamanaban, M., Masson, G.R., Perisic, O., Kaufman, J., Williams, R.L.

(2019) Science 366: 203-210

Released	2019-10-16
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	Ras-related GTP-binding protein A (protein) Ras-related GTP-binding protein C (protein)
Unique Ligands	9JE, GDP, GTP, MG

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6SB0 \| pdb_00006sb0	Download File View File

cryo-EM structure of mTORC1 bound to PRAS40-fused active RagA/C GTPases

Anandapadamanaban, M., Berndt, A., Masson, G.R., Perisic, O., Williams, R.L.

(2019) Science 366: 203-210

Released	2019-10-16
Method	ELECTRON MICROSCOPY 5.5 Å
Organisms	Homo sapiens
Macromolecule	Unique protein chains: 6
Unique Ligands	GDP, GTP

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6SB2 \| pdb_00006sb2	Download File View File

cryo-EM structure of mTORC1 bound to active RagA/C GTPases

Anandapadamanaban, M., Berndt, A., Masson, G.R., Perisic, O., Williams, R.L.

(2019) Science 366: 203-210

Released	2019-10-16
Method	ELECTRON MICROSCOPY 6.2 Å
Organisms	Homo sapiens
Macromolecule	Ras-related GTP-binding protein A (protein) Ras-related GTP-binding protein C (protein) Regulatory-associated protein of mTOR (protein) Target of rapamycin complex subunit LST8 (protein) mTOR,Serine/threonine-protein kinase mTOR,mTOR,Serine/threonine-protein kinase mTOR (protein)
Unique Ligands	GDP, GTP

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7OWG \| pdb_00007owg	Download File View File

human DEPTOR in a complex with mutant human mTORC1 A1459P

Heimhalt, M., Berndt, A., Wagstaff, J., Anandapadamanaban, M., Perisic, O., Maslen, S., McLaughlin, S., Yu, W.-H., Masson, G.R., Boland, A., Ni, X., Yamashita, K., Murshudov, G.N., Skehel, M., Freund, S.M., Williams, R.L.

(2021) Elife 10:

Released	2021-09-08
Method	ELECTRON MICROSCOPY 4.7 Å
Organisms	Homo sapiens
Macromolecule	DEP domain-containing mTOR-interacting protein (protein) Regulatory-associated protein of mTOR (protein) Serine/threonine-protein kinase mTOR (protein) Target of rapamycin complex subunit LST8 (protein)

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8RCH \| pdb_00008rch	Download File View File

CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, overall refinement

Anandapadamanaban, M., Hay, I.M., Perisic, O., Williams, R.L.

To be published

Released	2024-09-11
Method	ELECTRON MICROSCOPY 4 Å
Organisms	Homo sapiens
Macromolecule	Eukaryotic translation initiation factor 4E-binding protein 1 (protein) Regulatory-associated protein of mTOR (protein) Serine/threonine-protein kinase mTOR (protein) Target of rapamycin complex subunit LST8 (protein)
Unique Ligands	ANP, MG

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8RCK \| pdb_00008rck	Download File View File

CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused on one protomer copy.

Anandapadamanaban, M., Hay, I.M., Perisic, O., Williams, R.L.

To be published

Released	2024-09-11
Method	ELECTRON MICROSCOPY 3.4 Å
Organisms	Homo sapiens
Macromolecule	Eukaryotic translation initiation factor 4E-binding protein 1 (protein) Regulatory-associated protein of mTOR (protein) Serine/threonine-protein kinase mTOR (protein) Target of rapamycin complex subunit LST8 (protein)
Unique Ligands	ANP, MG

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8RCN \| pdb_00008rcn	Download File View File

CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused region of mTOR and RAPTOR on one protomer copy.

Anandapadamanaban, M., Hay, I.M., Perisic, O., Williams, R.L.

To be published

Released	2024-09-11
Method	ELECTRON MICROSCOPY 3.1 Å
Organisms	Homo sapiens
Macromolecule	Eukaryotic translation initiation factor 4E-binding protein 1 (protein) Regulatory-associated protein of mTOR (protein) Serine/threonine-protein kinase mTOR (protein)
Unique Ligands	ANP, MG

2LV5 | pdb_00002lv5

NMR solution structure of PA1075 from Pseudomonas Aeruginosa

4B0A | pdb_00004b0a

The high-resolution structure of yTBP-yTAF1 identifies conserved and competing interaction surfaces in transcriptional activation

4MEW | pdb_00004mew

Structure of the core fragment of human PR70

4ZZL | pdb_00004zzl

MexR R21W derepressor mutant causing multidrug resistance in P. aeruginosa by mexAB-oprM efflux pump expression

5JPX | pdb_00005jpx

Solution structure of the TRIM21 B-box2 (B2)

5LBN | pdb_00005lbn

High-resolution crystal structure of the UBC core domain of UBE2E1/UbcH6

6FGA | pdb_00006fga

Crystal structure of TRIM21 E3 ligase, RING domain in complex with its cognate E2 conjugating enzyme UBE2E1

6S6A | pdb_00006s6a

Crystal structure of RagA-Q66L/RagC-T90N GTPase heterodimer complex

6S6D | pdb_00006s6d

Crystal structure of RagA-Q66L-GTP/RagC-S75N-GDP GTPase heterodimer complex

6SB0 | pdb_00006sb0

cryo-EM structure of mTORC1 bound to PRAS40-fused active RagA/C GTPases

6SB2 | pdb_00006sb2

cryo-EM structure of mTORC1 bound to active RagA/C GTPases

7OWG | pdb_00007owg

human DEPTOR in a complex with mutant human mTORC1 A1459P

8RCH | pdb_00008rch

CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, overall refinement

8RCK | pdb_00008rck

CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused on one protomer copy.

8RCN | pdb_00008rcn

CryoEM structure of mTORC1 with a paediatric kidney cancer-associated 1455-EWED-1458 duplication in mTOR, Focused region of mTOR and RAPTOR on one protomer copy.

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

2LV5 | pdb_00002lv5

4B0A | pdb_00004b0a

4MEW | pdb_00004mew

4ZZL | pdb_00004zzl

5JPX | pdb_00005jpx

5LBN | pdb_00005lbn

6FGA | pdb_00006fga

6S6A | pdb_00006s6a

6S6D | pdb_00006s6d

6SB0 | pdb_00006sb0

6SB2 | pdb_00006sb2

7OWG | pdb_00007owg

8RCH | pdb_00008rch

8RCK | pdb_00008rck

8RCN | pdb_00008rcn