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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Citation Author = "Andrews, S.F."

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Search Summary

This query matches 47 Structures.

Refinements

Structure Determination Methodology

experimental (47)

Scientific Name of Source Organism

	Homo sapiens (41)
	Influenza A virus (13)
	Human herpesvirus 4 strain B95-8 (4)
	Influenza A virus (A/New Caledonia/20/1999(H1N1)) (4)
	Influenza A virus (A/Singapore/1/1957(H2N2)) (4)
	Macaca fascicularis (4)
	Influenza A virus (A/Indiana/10/2011(H3N2)) (2)
	human gammaherpesvirus 4 (2)
	Influenza A virus (A/Canada/720/2005(H2N2)) (1)
	Influenza A virus (A/Shanghai/JS01/2013(H7N9)) (1)

More...

Taxonomy

	Eukaryota (47)
	Riboviria (25)
	Duplodnaviria (6)

Experimental Method

	ELECTRON MICROSCOPY (24)
	X-RAY DIFFRACTION (23)

Polymer Entity Type

Protein (47)

Refinement Resolution (Å)

	1.0 - 1.5 (2)
	1.5 - 2.0 (7)
	2.0 - 2.5 (7)
	2.5 - 3.0 (8)
	3.0 - 3.5 (12)
	3.5 - 4.0 (10)
	4.0 - 4.5 (1)

Release Date

	2015 - 2019 (6)
	2020 - 2024 (37)
	2025 - 2029 (4)

Enzyme Classification Name

Hydrolases (3)

Symmetry Type

	Asymmetric (26)
	Cyclic (21)

SCOP Classification

	All beta proteins (9)
	Coiled coil proteins (1)
	Artifacts (2)

AllSelected

1 to 25 of 47 Structures

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5TR8 \| pdb_00005tr8	Download File View File

Crystal structure of vaccine-elicited pan- influenza H1N1 neutralizing murine antibody 441D6.

Joyce, M.G., Kanekiyo, M., Mascola, J.R., Graham, B.S., Kwong, P.D.

(2019) Nat Immunol 20: 362-372

Released	2018-05-09
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Mus musculus
Macromolecule	441D6 Fab Heavy chain (protein) 441D6 Fab Light chain (protein)
Unique Ligands	NI

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5TY6 \| pdb_00005ty6	Download File View File

Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 13-1b02 Fab.

Joyce, M.G., Andrews, S.F., Mascola, J.R., McDermott, A.B., Kwong, P.D.

(2017) Sci Immunol 2:

Released	2017-10-25
Method	X-RAY DIFFRACTION 1.361 Å
Organisms	Homo sapiens
Macromolecule	VRC 315 13-1b02 Fab Heavy chain (protein) VRC 315 13-1b02 Fab Light chain (protein)
Unique Ligands	GOL

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5U4R \| pdb_00005u4r	Download File View File

Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 53-1A09 Fab.

Joyce, M.G., Andrews, S.F., Mascola, J.R., McDermott, A.B., Kwong, P.D.

(2017) Sci Immunol 2:

Released	2017-11-15
Method	X-RAY DIFFRACTION 1.762 Å
Organisms	Homo sapiens
Macromolecule	VRC 315 53-1A09 Fab Heavy chain (protein) VRC 315 53-1A09 Fab Light chain (protein)

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5WCA \| pdb_00005wca	Download File View File

Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 27-1C08 Fab.

Joyce, M.G., Andrews, S.F., Mascola, J.R., McDermott, A.B., Kwong, P.D.

(2017) Sci Immunol 2:

Released	2017-08-02
Method	X-RAY DIFFRACTION 1.369 Å
Organisms	Homo sapiens
Macromolecule	VRC315 27-1C08 Fab Heavy chain (protein) VRC315 27-1C08 Fab Light chain (protein)

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5WCC \| pdb_00005wcc	Download File View File

Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 02-1F07 Fab.

Joyce, M.G., Andrews, S.F., Mascola, J.R., McDermott, A.B., Kwong, P.D.

(2017) Sci Immunol 2:

Released	2017-12-13
Method	X-RAY DIFFRACTION 2.461 Å
Organisms	Homo sapiens
Macromolecule	VRC 315 02-1F07 Fab Heavy chain (protein) VRC 315 02-1F07 Fab Light chain (protein)
Unique Ligands	15P, GOL, SO4

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5WCD \| pdb_00005wcd	Download File View File

Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 04-1D02 Fab.

Joyce, M.G., Andrews, S.F., Mascola, J.R., McDermott, A.B., Kwong, P.D.

(2017) Sci Immunol 2:

Released	2017-08-23
Method	X-RAY DIFFRACTION 1.814 Å
Organisms	Homo sapiens
Macromolecule	VRC315 04-1D02 Fab Heavy chain (protein) VRC315 04-1D02 Fab Light chain (protein)
Unique Ligands	PO4, SO4

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6WIY \| pdb_00006wiy	Download File View File

Crystal structure of Fab 54-1G05

Wu, N.C., Wilson, I.A.

(2020) Cell Host Microbe 28: 434

Released	2020-07-01
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Homo sapiens
Macromolecule	Fab 54-1G05 heavy chain (protein) Fab 54-1G05 light chain (protein)
Unique Ligands	GOL

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6WIZ \| pdb_00006wiz	Download File View File

Crystal structure of Fab 54-1G05 bound to H1 influenza hemagglutinin

Wu, N.C., Wilson, I.A.

(2020) Cell Host Microbe 28: 434

Released	2020-07-01
Method	X-RAY DIFFRACTION 4.2 Å
Organisms	Homo sapiens Influenza A virus
Macromolecule	Fab 54-1G05 heavy chain (protein) Fab 54-1G05 light chain (protein) Hemagglutinin HA1 (protein) Hemagglutinin HA2 (protein)
Unique Ligands	NAG

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6WJ0 \| pdb_00006wj0	Download File View File

Crystal structure of Fab 54-4H03

Wu, N.C., Wilson, I.A.

(2020) Cell Host Microbe 28: 434

Released	2020-07-01
Method	X-RAY DIFFRACTION 1.802 Å
Organisms	Homo sapiens
Macromolecule	Fab 54-4H03 heavy chain (protein) Fab 54-4H03 light chain (protein)
Unique Ligands	GOL

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6WJ1 \| pdb_00006wj1	Download File View File

Crystal structure of Fab 54-4H03 bound to H1 influenza hemagglutinin

Wu, N.C., Wilson, I.A.

(2020) Cell Host Microbe 28: 434

Released	2020-07-01
Method	X-RAY DIFFRACTION 3.503 Å
Organisms	Homo sapiens Influenza A virus
Macromolecule	Fab 54-4H03 heavy chain (protein) Fab 54-4H03 light chain (protein) Hemagglutinin HA1 chain (protein) Hemagglutinin HA2 chain (protein)
Unique Ligands	NAG
Unique branched monosaccharides	BMA, FUC, MAN, NAG

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6WXL \| pdb_00006wxl	Download File View File

Cryo-EM structure of the VRC315 clinical trial, vaccine-elicited, human antibody 1D12 in complex with an H7 SH13 HA trimer

Gorman, J., Kwong, P.D.

(2022) Structure

Released	2021-06-09
Method	ELECTRON MICROSCOPY 2.76 Å
Organisms	Homo sapiens Influenza A virus (A/Shanghai/JS01/2013(H7N9))
Macromolecule	1D12 Light chain (protein) 1D21 Heavy chain (protein) Hemagglutinin HA1 chain (protein) Hemagglutinin HA2 chain (protein)
Unique Ligands	NAG

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7L0L \| pdb_00007l0l	Download File View File

Cryo-EM structure of the VRC316 clinical trial, vaccine-elicited, human antibody 316-310-1B11 in complex with an H2 CAN05 HA trimer

Gorman, J., Kwong, P.D.

(2022) Nat Med 28: 373-382

Released	2021-11-03
Method	ELECTRON MICROSCOPY 2.85 Å
Organisms	Homo sapiens Influenza A virus (A/Canada/720/2005(H2N2))
Macromolecule	316-310-1B11 Heavy Chain (protein) 316-310-1B11 Light Chain (protein) Hemagglutinin HA1 chain (protein) Hemagglutinin HA2 chain (protein)
Unique Ligands	NAG

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7MFG \| pdb_00007mfg	Download File View File

Cryo-EM structure of the VRC310 clinical trial, vaccine-elicited, human antibody 310-030-1D06 Fab in complex with an H1 NC99 HA trimer

Gorman, J., Kwong, P.D.

(2022) Nat Med 28: 373-382

Released	2021-11-03
Method	ELECTRON MICROSCOPY 3.87 Å
Organisms	Homo sapiens Influenza A virus
Macromolecule	310-030-1D06 Heavy (protein) 310-030-1D06 Light (protein) Hemagglutinin HA1 chain (protein) Hemagglutinin HA2 chain (protein)
Unique Ligands	NAG
Unique branched monosaccharides	BMA, NAG

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7S07 \| pdb_00007s07	Download File View File

Crystal structure of Epstein-Barr virus glycoprotein gH/gL/gp42-peptide in complex with human neutralizing antibodies 769B10 and 769C2

Chen, W.-H., Kanekiyo, M., Cohen, J.I., Joyce, M.G.

(2022) Immunity 55: 2135-2148.e6

Released	2022-11-09
Method	X-RAY DIFFRACTION 3.29 Å
Organisms	Homo sapiens human gammaherpesvirus 4
Macromolecule	Unique protein chains: 7
Unique Ligands	NAG

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7S08 \| pdb_00007s08	Download File View File

Crystal structure of Epstein-Barr virus gH/gL targeting antibody 770F7

Chen, W.-H., Joyce, M.G.

(2022) Immunity 55: 2135-2148.e6

Released	2022-11-09
Method	X-RAY DIFFRACTION 2.42 Å
Organisms	Homo sapiens
Macromolecule	770F7 Fab Heavy chain (protein) 770F7 Fab Light chain (protein)
Unique Ligands	GOL

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7S0J \| pdb_00007s0j	Download File View File

Crystal structure of Epstein-Barr virus gH/gL targeting antibody 769B10

Chen, W.-H., Kanekiyo, M., Cohen, J.I., Joyce, M.G.

(2022) Immunity 55: 2135-2148.e6

Released	2022-11-09
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Homo sapiens
Macromolecule	769B10 Fab Heavy chain (protein) 769B10 Fab Light chain (protein)
Unique Ligands	GOL

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7S1B \| pdb_00007s1b	Download File View File

Crystal structure of Epstein-Barr virus glycoproteins gH/gL/gp42-peptide in complex with human neutralizing antibodies 769C2 and 770F7

Chen, W.-H., Cohen, J.I., Kanekiyo, M., Joyce, M.G.

(2022) Immunity 55: 2135-2148.e6

Released	2022-11-09
Method	X-RAY DIFFRACTION 3.03 Å
Organisms	Homo sapiens human gammaherpesvirus 4
Macromolecule	Unique protein chains: 7
Unique Ligands	NAG

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8D21 \| pdb_00008d21	Download File View File

Cryo-EM structure of the VRC321 clinical trial, vaccine-elicited, human antibody 1B06 in complex with a stabilized NC99 HA trimer

Gorman, J., Kwong, P.D.

(2023) Sci Transl Med 15: eade4976-eade4976

Released	2023-04-12
Method	ELECTRON MICROSCOPY 3.96 Å
Organisms	Homo sapiens Influenza A virus
Macromolecule	1B06 Heavy Chain (protein) 1B06 Light Chain (protein) Hemagglutinin HA1 chain (protein) Hemagglutinin HA2 chain (protein)
Unique Ligands	NAG
Unique branched monosaccharides	BMA, NAG

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8GAT \| pdb_00008gat	Download File View File

Structure of human NDS.1 Fab and 1G01 Fab in complex with influenza virus neuraminidase from A/Indiana/10/2011 (H3N2v), based on consensus cryo-EM map with only Fab 1G01 resolved

Tsybovsky, Y., Lederhofer, J., Kwong, P.D., Kanekiyo, M.

(2024) Immunity 57: 574-586.e7

Released	2024-02-28
Method	ELECTRON MICROSCOPY 3 Å
Organisms	Homo sapiens Influenza A virus (A/Indiana/10/2011(H3N2))
Macromolecule	Fab 1G01, heavy chain (protein) Fab 1G01, light chain (protein) Vasodilator-stimulated phosphoprotein, Neuraminidase chimera (protein)
Unique Ligands	NAG

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8GAU \| pdb_00008gau	Download File View File

Structure of human NDS.1 Fab and 1G01 Fab in complex with influenza virus neuraminidase from A/Indiana/10/2011 (H3N2v)

Tsybovsky, Y., Lederhofer, J., Kwong, P.D., Kanekiyo, M.

(2024) Immunity 57: 574-586.e7

Released	2024-02-28
Method	ELECTRON MICROSCOPY 3.6 Å
Organisms	Homo sapiens Influenza A virus (A/Indiana/10/2011(H3N2))
Macromolecule	Fab 1G01, heavy chain (protein) Fab 1G01, light chain (protein) Fab NDS.1, heavy chain (protein) Fab NDS.1, light chain (protein) Vasodilator-stimulated phosphoprotein, Neuraminidase chimera (protein)
Unique Ligands	NAG

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8GAV \| pdb_00008gav	Download File View File

Structure of human NDS.3 Fab in complex with influenza virus neuraminidase from A/Darwin/09/2021 (H3N2)

Tsybovsky, Y., Lederhofer, J., Kwong, P.D., Kanekiyo, M.

(2024) Immunity 57: 574-586.e7

Released	2024-02-28
Method	ELECTRON MICROSCOPY 2.7 Å
Organisms	Homo sapiens Influenza A virus
Macromolecule	Fab NDS.3, heavy chain (protein) Fab NDS.3, light chain (protein) Neuraminidase (protein)
Unique Ligands	NAG

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8SEF \| pdb_00008sef	Download File View File

Crystal structure of Cy137C02, a monoclonal antibody isolated from macaques immunized with an Epstein-Barr virus glycoprotein 350 (gp350) nanoparticle vaccine

Joyce, M.G., Jensen, J.L., Chen, W.H., Kanekiyo, M.

(2025) Immunity 58: 295

Released	2024-04-17
Method	X-RAY DIFFRACTION 2.47 Å
Organisms	Macaca fascicularis
Macromolecule	Cy137C02 Fab heavy chain (protein) Cy137C02 Fab light chain (protein)
Unique Ligands	GOL, SO4

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8SGA \| pdb_00008sga	Download File View File

Crystal structure of 770E11, a monoclonal antibody isolated from a human Epstein-Barr virus seropositive donor

Chen, W.H., Jensen, J.L., Joyce, M.G.

(2025) Immunity 58: 295

Released	2024-04-17
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	770E11 Fab heavy chain (protein) 770E11 Fab light chain (protein)
Unique Ligands	GOL
Unique branched monosaccharides	BMA, NAG

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8SGG \| pdb_00008sgg	Download File View File

Crystal structure of Cy137D09, a monoclonal antibody isolated from macaques immunized with an Epstein-Barr virus glycoprotein 350 (gp350) nanoparticle vaccine

Joyce, M.G., Jensen, J.L., Chen, W.H., Kanekiyo, M.

(2025) Immunity 58: 295

Released	2024-04-17
Method	X-RAY DIFFRACTION 2.03 Å
Organisms	Macaca fascicularis
Macromolecule	Cy137D09 Fab heavy chain (protein) Cy137D09 Fab light chain (protein)
Unique Ligands	GOL

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8SGN \| pdb_00008sgn	Download File View File

Crystal structure of Epstein-Barr virus glycoprotein 350 (gp350) in complex with Cy651H02, a monoclonal antibody isolated from macaques immunized with a gp350 nanoparticle vaccine

Joyce, M.G., Jensen, J.L., Chen, W.H., Kanekiyo, M.

(2025) Immunity 58: 295

Released	2024-04-17
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Human herpesvirus 4 strain B95-8 Macaca fascicularis
Macromolecule	Cy651H02 Fab heavy chain (protein) Cy651H02 Fab light chain (protein) Envelope glycoprotein gp350 (protein)
Unique Ligands	EDO, NAG, TRS
Unique branched monosaccharides	FUC, NAG

1 to 25 of 47 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

5TR8 | pdb_00005tr8

5TY6 | pdb_00005ty6

5U4R | pdb_00005u4r

5WCA | pdb_00005wca

5WCC | pdb_00005wcc

5WCD | pdb_00005wcd

6WIY | pdb_00006wiy

6WIZ | pdb_00006wiz

6WJ0 | pdb_00006wj0

6WJ1 | pdb_00006wj1

6WXL | pdb_00006wxl

7L0L | pdb_00007l0l

7MFG | pdb_00007mfg

7S07 | pdb_00007s07

7S08 | pdb_00007s08

7S0J | pdb_00007s0j

7S1B | pdb_00007s1b

8D21 | pdb_00008d21

8GAT | pdb_00008gat

8GAU | pdb_00008gau

8GAV | pdb_00008gav

8SEF | pdb_00008sef

8SGA | pdb_00008sga

8SGG | pdb_00008sgg

8SGN | pdb_00008sgn