RCSB PDB: Search

Warning You are using a web browser that we do not support. Our website will not work properly. Please update to a newer version or download a new web browser, such as Chrome or Firefox.

Help

Help

RCSB PDB

Deposit
- PDBx/mmCIF file
- pdb_extract
- SF-Tool
- Ligand Expo
- MAXIT
- Validation Server
- Validation API
- Information for Journals
- Validation Task Forces
- wwPDB OneDep System
- PDB-IHM
Search
Visualize
Analyze
Download
Learn
- Training Courses
- Guide to PDB Data
- Molecule of the Month
- Educational Resources
- Curricula
- Browse
- News
- SciArt Galleries
- Irving Geis
- David Goodsell
About
Careers
COVID-19

233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

	Include CSM
Advanced Search \| Browse Annotations		Help

Search
Query History
Browse Annotations
MyPDB

QUERY: Structure Author = "Morgan, H.P."

MyPDB Login

Search API

Advanced Search Query Builder

Help

Full Text

Structure Attributes

Help

NOT

Count

Add Subquery

Chemical Attributes

Sequence Similarity

Sequence Motif

Structure Similarity

Structure Motif

Chemical Similarity

Return

grouped by

Include Computed Structure Models (CSM)

Count

Clear

Search Summary

This query matches 32 Structures.

Refinements

Structure Determination Methodology

experimental (32)

Scientific Name of Source Organism

	Leishmania mexicana (13)
	Homo sapiens (9)
	Trypanosoma brucei brucei (6)
	Trypanosoma cruzi strain CL Brener (2)
	Salmonella enterica subsp. enterica serovar Typhimurium (1)
	Trypanosoma cruzi (1)

Taxonomy

	Eukaryota (31)
	Bacteria (1)

Experimental Method

X-RAY DIFFRACTION (32)

Polymer Entity Type

Protein (32)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (4)
	2.0 - 2.5 (14)
	2.5 - 3.0 (11)
	3.0 - 3.5 (1)
	> 4.5 (1)

Release Date

	2005 - 2009 (3)
	2010 - 2014 (29)

Enzyme Classification Name

	Transferases (25)
	Isomerases (2)

Symmetry Type

	Dihedral (23)
	Asymmetric (8)
	Cyclic (2)

SCOP Classification

	Alpha and beta proteins (a/b) (8)
	All beta proteins (9)
	All alpha proteins (2)
	Artifacts (2)

AllSelected

1 to 25 of 32 Structures

Page 1 of 2

Sort by

Explore in 3D

3HQN \| pdb_00003hqn	Download File View File

Apo crystal structure of Leishmania mexicana(LmPYK)pyruvate kinase

Morgan, H.P., Walkinshaw, M.D.

(2010) J Biological Chem 285: 12892-12898

Released	2010-02-16
Method	X-RAY DIFFRACTION 2 Å
Organisms	Leishmania mexicana
Macromolecule	Pyruvate kinase (protein)
Unique Ligands	GOL, K, SO4

Explore in 3D

3HQO \| pdb_00003hqo	Download File View File

Crystal structures of Leishmania mexicana pyruvate kinase (LmPYK) in complex with ATP and Oxalate

Morgan, H.P., Walkinshaw, M.D.

(2010) J Biological Chem 285: 12892-12898

Released	2010-02-16
Method	X-RAY DIFFRACTION 3.4 Å
Organisms	Leishmania mexicana
Macromolecule	Pyruvate kinase (protein)
Unique Ligands	ATP, K, MG, OXL

Explore in 3D

3HQP \| pdb_00003hqp	Download File View File

Crystal structure of Leishmania mexicana pyruvate kinase (LmPYK) in complex with ATP, Oxalate and fructose 2,6 bisphosphate

Morgan, H.P., Walkinshaw, M.D.

(2010) J Biological Chem 285: 12892-12898

Released	2010-02-16
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Leishmania mexicana
Macromolecule	Pyruvate kinase (protein)
Unique Ligands	ATP, FDP, GOL, K, MG, OXL

Explore in 3D

3HQQ \| pdb_00003hqq	Download File View File

Crystal structure of Leishmania mexicana pyruvate kinase (LmPYK) in complex with Fructose 2,6 bisphosphate

Morgan, H.P., Walkinshaw, M.D.

(2010) J Biological Chem 285: 12892-12898

Released	2010-02-16
Method	X-RAY DIFFRACTION 5.07 Å
Organisms	Leishmania mexicana
Macromolecule	Pyruvate kinase (protein)
Unique Ligands	FDP

Explore in 3D

3I2Z \| pdb_00003i2z	Download File View File

Structure of cold shock protein E from Salmonella typhimurium

Morgan, H.P., McNae, I., Wear, M.A., Gallagher, M., Walkinshaw, M.D.

(2009) Acta Crystallogr Sect F Struct Biol Cryst Commun 65: 1240-1245

Released	2009-12-22
Method	X-RAY DIFFRACTION 1.1 Å
Organisms	Salmonella enterica subsp. enterica serovar Typhimurium
Macromolecule	RNA chaperone, negative regulator of cspA transcription (protein)

Explore in 3D

3IGY \| pdb_00003igy	Download File View File

Crystal structures of Leishmania mexicana phosphoglycerate mutase at high cobalt concentrations

Nowicki, M.W., Kuaprasert, B., McNae, I.W., Morgan, H.P., Harding, M.M., Michels, P.A., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

(2009) J Mol Biology 394: 535-543

Released	2009-10-27
Method	X-RAY DIFFRACTION 2.003 Å
Organisms	Leishmania mexicana
Macromolecule	Cofactor-independent phosphoglycerate mutase (protein)
Unique Ligands	2PG, 3PG, CO, NA

Explore in 3D

3IGZ \| pdb_00003igz	Download File View File

Crystal structures of Leishmania mexicana phosphoglycerate mutase at low cobalt concentration

Nowicki, M.W., Kuaprasert, B., McNae, I.W., Morgan, H.P., Harding, M.M., Michels, P.A., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

(2009) J Mol Biology 394: 535-543

Released	2009-10-27
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Leishmania mexicana
Macromolecule	Cofactor-independent phosphoglycerate mutase (protein)
Unique Ligands	2PG, 3PG, CO, NA

Explore in 3D

3IS4 \| pdb_00003is4	Download File View File

Crystal structure of Leishmania mexicana pyruvate kinase (LmPYK)in complex with 1,3,6,8-pyrenetetrasulfonic acid

Walkinshaw, M.D., Morgan, H.P.

(2010) Acta Crystallogr Sect F Struct Biol Cryst Commun 66: 215-218

Released	2010-03-23
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Leishmania mexicana
Macromolecule	Pyruvate kinase (protein)
Unique Ligands	GOL, PTK

Explore in 3D

3KTX \| pdb_00003ktx	Download File View File

Crystal structure of Leishmania mexicana pyruvate kinase (LmPYK)in complex with 1,3,6,8-pyrenetetrasulfonic acid

Morgan, H.P., Walkinshaw, M.D.

(2010) Acta Crystallogr Sect F Struct Biol Cryst Commun 66: 215-218

Released	2010-02-09
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Leishmania mexicana
Macromolecule	Pyruvate kinase (protein)
Unique Ligands	GOL, PTK

Explore in 3D

3OXU \| pdb_00003oxu	Download File View File

Complement components factor H CCP19-20 and C3d in complex

Morgan, H.P., Schmidt, C.Q., Guariento, M., Gillespie, D., Herbert, A.P., Mertens, H., Blaum, B.S., Svergun, D., Johansson, C.M., Uhrin, D., Barlow, P.N., Hannan, J.P.

(2011) Nat Struct Mol Biol 18: 463-470

Released	2011-02-16
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens
Macromolecule	Complement C3 (protein) HF protein (protein)
Unique Ligands	GOL

Explore in 3D

3PP7 \| pdb_00003pp7	Download File View File

Crystal structure of Leishmania mexicana pyruvate kinase in complex with the drug suramin, an inhibitor of glycolysis.

Morgan, H.P., Auld, D.S., McNae, I.W., Nowicki, M.W., Michels, P.A.M., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

(2011) J Biological Chem 286: 31232-31240

Released	2010-12-15
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Leishmania mexicana
Macromolecule	Pyruvate kinase (protein)
Unique Ligands	GOL, K, PTK, SVR

Explore in 3D

3QV6 \| pdb_00003qv6	Download File View File

Crystal structure of Leishmania mexicana pyruvate kinase(LmPYK)in complex with acid blue 80.

Morgan, H.P., Auld, D.S., McNae, I.W., Nowicki, M.W., Michels, P.A.M., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

(2011) J Biological Chem 286: 31232-31240

Released	2011-06-29
Method	X-RAY DIFFRACTION 2.85 Å
Organisms	Leishmania mexicana
Macromolecule	Pyruvate kinase (protein)
Unique Ligands	K, PO4, QV6

Explore in 3D

3QV7 \| pdb_00003qv7	Download File View File

Crystal structure of Leishmania mexicana pyruvate kinase(LmPYK)in complex with ponceau S and acid blue 25.

Morgan, H.P., Auld, D.S., McNae, I.W., Nowicki, M.W., Michels, P.A.M., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

(2011) J Biological Chem 286: 31232-31240

Released	2011-06-29
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Leishmania mexicana
Macromolecule	Pyruvate kinase (protein)
Unique Ligands	K, QV7, QV8, SO4

Explore in 3D

3QV8 \| pdb_00003qv8	Download File View File

Crystal structure of Leishmania mexicana pyruvate kinase(LmPYK)in complex with benzothiazole-2,5-disulfonic acid.

Morgan, H.P., Auld, D.S., McNae, I.W., Nowicki, M.W., Michels, P.A.M., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

(2011) J Biological Chem 286: 31232-31240

Released	2011-06-29
Method	X-RAY DIFFRACTION 2.45 Å
Organisms	Leishmania mexicana
Macromolecule	Pyruvate kinase (protein)
Unique Ligands	PO4, S62

Explore in 3D

3QV9 \| pdb_00003qv9	Download File View File

Crystal structure of Trypanosoma cruzi pyruvate kinase(TcPYK)in complex with ponceau S.

Morgan, H.P., Auld, D.S., McNae, I.W., Nowicki, M.W., Michels, P.A.M., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

(2011) J Biological Chem 286: 31232-31240

Released	2011-07-06
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Trypanosoma cruzi
Macromolecule	Pyruvate kinase 2 (protein)
Unique Ligands	K, PO4, QV7

Explore in 3D

3R62 \| pdb_00003r62	Download File View File

Structure of complement regulator Factor H mutant, T1184R.

Morgan, H.P., Jiang, J., Herbert, A.P., Kavanagh, D., Uhran, D., Barlow, P.N., Hannan, J.P.

(2011) Acta Crystallogr D Biol Crystallogr 67: 593-600

Released	2011-06-29
Method	X-RAY DIFFRACTION 1.52 Å
Organisms	Homo sapiens
Macromolecule	Complement factor H (protein)
Unique Ligands	GOL

Explore in 3D

3RJ3 \| pdb_00003rj3	Download File View File

Complement components factor H CCP19-20 (S1191L mutant) and C3D in complex

Morgan, H.P., Hannan, J.P.

(2012) Biochemistry 51: 1874-1884

Released	2012-03-14
Method	X-RAY DIFFRACTION 2.35 Å
Organisms	Homo sapiens
Macromolecule	Complement C3d fragment (protein) Complement Factor H-related protein 1 (protein)
Unique Ligands	GOL

Explore in 3D

3SRD \| pdb_00003srd	Download File View File

Human M2 pyruvate kinase in complex with fructose 1-6 bisphosphate and Oxalate.

Morgan, H.P., O'Reilly, F., Palmer, R., McNae, I.W., Nowicki, M.W., Wear, M.A., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

To be published

Released	2012-08-08
Method	X-RAY DIFFRACTION 2.902 Å
Organisms	Homo sapiens
Macromolecule	Pyruvate kinase isozymes M1/M2 (protein)
Unique Ligands	FBP, GOL, K, MG, OXL

Explore in 3D

3SRF \| pdb_00003srf	Download File View File

Human M1 pyruvate kinase

Morgan, H.P., O'Reilly, F., Palmer, R., McNae, I.W., Nowicki, M.W., Wear, M.A., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

To be published

Released	2012-08-08
Method	X-RAY DIFFRACTION 2.845 Å
Organisms	Homo sapiens
Macromolecule	Pyruvate kinase isozymes M1/M2 (protein)
Unique Ligands	GOL, K, MG, PO4, PYR

Explore in 3D

3SRH \| pdb_00003srh	Download File View File

Human M2 pyruvate kinase

Morgan, H.P., O'Reilly, F., Palmer, R., McNae, I.W., Nowicki, M.W., Wear, M.A., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

To be published

Released	2012-08-08
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Pyruvate kinase isozymes M1/M2 (protein)
Unique Ligands	PO4

Explore in 3D

3SRK \| pdb_00003srk	Download File View File

A new class of suicide inhibitor blocks nucleotide binding to pyruvate kinase

Morgan, H.P., Walsh, M., Blackburn, E.A., Wear, M.A., Boxer, M., Shen, M., McNae, I.W., Michels, P.A.M., Auld, D.S., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

To be published

Released	2012-07-18
Method	X-RAY DIFFRACTION 2.65 Å
Organisms	Leishmania mexicana
Macromolecule	Pyruvate kinase (protein)
Unique Ligands	K, LSA, PTK

Explore in 3D

3SW0 \| pdb_00003sw0	Download File View File

Structure of the C-terminal region (modules 18-20) of complement regulator Factor H

Morgan, H.P., Guariento, M., Schmidt, C.Q., Barlow, P.N., Hannan, J.P.

(2012) PLoS One 7: e32187-e32187

Released	2012-03-14
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	Complement factor H (protein)
Unique Ligands	GOL, PO4

Explore in 3D

4FXF \| pdb_00004fxf	Download File View File

Structure of M2 pyruvate kinase in complex with phenylalanine

Walkinshaw, M.D., Morgan, H.P.

(2013) Proc Natl Acad Sci U S A 110: 5881-5886

Released	2013-03-27
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Homo sapiens
Macromolecule	Pyruvate kinase isozymes M1/M2 (protein)
Unique Ligands	ATP, FBP, K, MG, OXL

Explore in 3D

4FXJ \| pdb_00004fxj	Download File View File

Structure of M2 pyruvate kinase in complex with phenylalanine

Walkinshaw, M.D., Morgan, H.P.

(2013) Proc Natl Acad Sci U S A 110: 5881-5886

Released	2013-03-27
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	Pyruvate kinase isozymes M1/M2 (protein)
Unique Ligands	PHE, PO4

Explore in 3D

4HYV \| pdb_00004hyv	Download File View File

Pyruvate kinase (PYK) from Trypanosoma brucei in the presence of Magnesium, PEP and F26BP

Zhong, W., Morgan, H.P., McNae, I.W., Michels, P.A.M., Fothergill-Gilmore, L.A., Walkinshaw, M.D.

(2013) Acta Crystallogr D Biol Crystallogr 69: 1768-1779

Released	2013-09-11
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Trypanosoma brucei brucei
Macromolecule	Pyruvate kinase 1 (protein)
Unique Ligands	CL, FDP, GOL, K, MG, PEP

1 to 25 of 32 Structures

Page 1 of 2

Sort by

About
About Us
Citing Us
Publications
Team
Careers
Usage & Privacy

Support
Contact Us
Help
Website FAQ
Glossary
Service Status

RCSB PDB is hosted by

RCSB PDB is a member of the

RCSB Partners
Nucleic Acid Knowledgebase

wwPDB Partners
RCSB PDB
PDBe
PDBj
BMRB
EMDB

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

Prepare Data

Validate Data

Deposit Data

Help and Resources

Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

3HQN | pdb_00003hqn

3HQO | pdb_00003hqo

3HQP | pdb_00003hqp

3HQQ | pdb_00003hqq

3I2Z | pdb_00003i2z

3IGY | pdb_00003igy

3IGZ | pdb_00003igz

3IS4 | pdb_00003is4

3KTX | pdb_00003ktx

3OXU | pdb_00003oxu

3PP7 | pdb_00003pp7

3QV6 | pdb_00003qv6

3QV7 | pdb_00003qv7

3QV8 | pdb_00003qv8

3QV9 | pdb_00003qv9

3R62 | pdb_00003r62

3RJ3 | pdb_00003rj3

3SRD | pdb_00003srd

3SRF | pdb_00003srf

3SRH | pdb_00003srh

3SRK | pdb_00003srk

3SW0 | pdb_00003sw0

4FXF | pdb_00004fxf

4FXJ | pdb_00004fxj

4HYV | pdb_00004hyv