FBP

1,6-di-O-phosphono-beta-D-fructofuranose

Created:	1999-07-08
Last modified:	2020-07-17

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133 entries where FBP is found as a standalone ligand1 entries where FBP is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	34
Chiral Atom Count	4
Bond Count	34
Aromatic Bond Count	0

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Chemical Component Summary
Name	1,6-di-O-phosphono-beta-D-fructofuranose
Synonyms	BETA-FRUCTOSE-1,6-DIPHOSPHATE; FRUCTOSE-1,6-BISPHOSPHATE; 1,6-di-O-phosphono-beta-D-fructose; 1,6-di-O-phosphono-D-fructose; 1,6-di-O-phosphono-fructose
Systematic Name (OpenEye OEToolkits)	[(2R,3S,4S,5R)-2,3,4-trihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₆ H₁₄ O₁₂ P₂
Molecular Weight	340.116
Type	D-SACCHARIDE, BETA LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=P(O)(O)OCC1OC(O)(COP(=O)(O)O)C(O)C1O
SMILES	CACTVS	3.341	O[CH]1[CH](O)[C](O)(CO[P](O)(O)=O)O[CH]1CO[P](O)(O)=O
SMILES	OpenEye OEToolkits	1.5.0	C(C1C(C(C(O1)(COP(=O)(O)O)O)O)O)OP(=O)(O)O
Canonical SMILES	CACTVS	3.341	O[C@H]1[C@H](O)[C@@](O)(CO[P](O)(O)=O)O[C@@H]1CO[P](O)(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C([C@@H]1[C@H]([C@@H]([C@](O1)(COP(=O)(O)O)O)O)O)OP(=O)(O)O
InChI	InChI	1.03	InChI=1S/C6H14O12P2/c7-4-3(1-16-19(10,11)12)18-6(9,5(4)8)2-17-20(13,14)15/h3-5,7-9H,1-2H2,(H2,10,11,12)(H2,13,14,15)/t3-,4-,5+,6-/m1/s1
InChIKey	InChI	1.03	RNBGYGVWRKECFJ-ARQDHWQXSA-N

Drug Info: DrugBank

DrugBank ID	DB04551
Name	beta-D-fructofuranose 1,6-bisphosphate
Groups	experimental
Synonyms	1,6-di-O-phosphono-β-D-fructofuranose beta-D-fructofuranose 1,6-bisphosphate beta-D-Fructose 1,6-bisphosphate β-D-fructofuranose 1,6-bisphosphate

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Pyruvate kinase PKLR	MSIQENISSLQLRSWVSKSQRDLAKSILIGAPGGPAGYLRRASVAQLTQE...	unknown
Glycerol kinase	MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPGWVEHDP...	unknown
Solute carrier organic anion transporter family member 2A1	MGLLPKLGASQGSDTSTSRAGRCARSVFGNIKVFVLCQGLLQLCQLLYSA...	unknown	inhibitor

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682