RCSB PDB: Search

1B3N \| pdb_00001b3n	Download File View File

BETA-KETOACYL CARRIER PROTEIN SYNTHASE AS A DRUG TARGET, IMPLICATIONS FROM THE CRYSTAL STRUCTURE OF A COMPLEX WITH THE INHIBITOR CERULENIN.

Moche, M., Schneider, G., Edwards, P., Dehesh, K., Lindqvist, Y.

(1999) J Biological Chem 274: 6031-6034

Released	1999-04-06
Method	X-RAY DIFFRACTION 2.65 Å
Organisms	Escherichia coli K-12
Macromolecule	PROTEIN (KETOACYL ACYL CARRIER PROTEIN SYNTHASE 2) (protein)
Unique Ligands	CER

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1E5M \| pdb_00001e5m	Download File View File

Beta ketoacyl acyl carrier protein synthase II (KASII) from Synechocystis sp.

Moche, M., Edwards, P., Dehesh, K., Lindqvist, Y.

(2001) J Mol Biology 305: 491

Released	2001-01-16
Method	X-RAY DIFFRACTION 1.54 Å
Organisms	Synechocystis sp. PCC 6803
Macromolecule	BETA KETOACYL ACYL CARRIER PROTEIN SYNTHASE II (protein)

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1OQ4 \| pdb_00001oq4	Download File View File

The Crystal Structure of the Complex between Stearoyl Acyl Carrier Protein Desaturase from Ricinus Communis (Castor Bean) and Azide.

Moche, M., Ghoshal, A.K., Shanklin, J., Lindqvist, Y.

(2003) J Biological Chem 278: 25072-25080

Released	2003-05-13
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Ricinus communis
Macromolecule	Acyl-[acyl-carrier protein] desaturase (protein)
Unique Ligands	AZI, FE

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1OQ7 \| pdb_00001oq7	Download File View File

The crystal structure of the iron free (Apo-)form of Stearoyl Acyl Carrier Protein Desaturase from Ricinus Communis (Castor Bean).

Moche, M., Shanklin, J., Ghoshal, A.K., Lindqvist, Y.

(2003) J Biological Chem 278: 25072-25080

Released	2003-05-13
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Ricinus communis
Macromolecule	Acyl-[acyl-carrier protein] desaturase (protein)
Unique Ligands	SR

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1OQ9 \| pdb_00001oq9	Download File View File

The Crystal Structure of the Complex between Stearoyl Acyl Carrier Protein Desaturase from Ricinus Communis (Castor Bean) and Acetate.

Moche, M., Shanklin, J., Ghoshal, A.K., Lindqvist, Y.

(2003) J Biological Chem 278: 25072-25080

Released	2003-05-13
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Ricinus communis
Macromolecule	Acyl-[acyl-carrier protein] desaturase (protein)
Unique Ligands	ACT, FE

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1OQB \| pdb_00001oqb	Download File View File

The Crystal Structure of the one-iron form of the di-iron center in Stearoyl Acyl Carrier Protein Desaturase from Ricinus Communis (Castor Bean).

Moche, M., Shanklin, J., Ghoshal, A.K., Lindqvist, Y.

(2003) J Biological Chem 278: 25072-25080

Released	2003-05-13
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Ricinus communis
Macromolecule	Acyl-[acyl-carrier protein] desaturase (protein)
Unique Ligands	FE2

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2G6V \| pdb_00002g6v	Download File View File

The crystal structure of ribD from Escherichia coli

Stenmark, P., Moche, M., Gurmu, D., Nordlund, P., Structural Proteomics in Europe (SPINE)

(2007) J Mol Biology 373: 48-64

Released	2007-02-06
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Escherichia coli
Macromolecule	Riboflavin biosynthesis protein ribD (protein)

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2J2F \| pdb_00002j2f	Download File View File

The T199D Mutant of Stearoyl Acyl Carrier Protein Desaturase from Ricinus Communis (Castor Bean)

Guy, J.E., Abreu, I.A., Moche, M., Lindqvist, Y., Whittle, E., Shanklin, J.

(2006) Proc Natl Acad Sci U S A 103: 17220

Released	2006-10-23
Method	X-RAY DIFFRACTION 2.65 Å
Organisms	Ricinus communis
Macromolecule	ACYL-[ACYL-CARRIER-PROTEIN] DESATURASE (protein)
Unique Ligands	FE

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2J8Q \| pdb_00002j8q	Download File View File

Crystal structure of human cleavage and polyadenylation specificity factor 5 (CPSF5) in complex with a sulphate ion.

Moche, M., Stenmark, P., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg, S.L., Hogbom, M., Johansson, I., Karlberg, T., Kosinska, U., Kotenyova, T., Magnusdottir, A., Nilsson, M.E., Nilsson-Ehle, P., Nyman, T., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Upsten, M., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Welin, M., Nordlund, P.

(2008) Proteins 73: 1047

Released	2006-11-13
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Homo sapiens
Macromolecule	CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR 5 (protein)
Unique Ligands	SO4

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2J91 \| pdb_00002j91	Download File View File

Crystal structure of Human Adenylosuccinate Lyase in complex with AMP

Stenmark, P., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kosinska, U., Kotenyova, T., Magnusdottir, A., Nilsson, M.E., Nilsson-Ehle, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Uppsten, M., Thorsell, A.G., van Den Berg, S., Wallden, K., Weigelt, J., Nordlund, P.

To be published

Released	2006-11-07
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	ADENYLOSUCCINATE LYASE (protein)
Unique Ligands	AMP, CL, GOL

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2JAK \| pdb_00002jak	Download File View File

Human PP2A regulatory subunit B56g

Magnusdottir, A., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kotenyova, T., Lundgren, S., Moche, M., Nilsson, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Upsten, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Nordlund, P.

(2009) Proteins 74: 212

Released	2006-12-04
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM (protein)

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2JBH \| pdb_00002jbh	Download File View File

Human phosphoribosyl transferase domain containing 1

Welin, M., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Eklund, H., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Nordlund, P.

(2010) FEBS J 277: 4920

Released	2006-12-20
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Homo sapiens
Macromolecule	PHOSPHORIBOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 (protein)
Unique Ligands	5GP, CA, PO4

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2JCN \| pdb_00002jcn	Download File View File

The crystal structure of BAK1 - a mitochondrial apoptosis regulator

Moche, M., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Johansson, I., Karlberg, T., Kosinska, U., Kotenyova, T., Lundgren, S., Nilsson, M.E., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Upsten, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2007-01-04
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens
Macromolecule	BCL-2 HOMOLOGOUS ANTAGONIST/KILLER (protein)
Unique Ligands	SO4

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2JEO \| pdb_00002jeo	Download File View File

Crystal structure of human uridine-cytidine kinase 1

Kosinska, U., Stenmark, P., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg Schiavone, L., Hogbom, M., Johansson, I., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E.P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Sundstrom, M., Uppenberg, J., Uppsten, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Welin, M., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2007-01-30
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	URIDINE-CYTIDINE KINASE 1 (protein)

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2JGY \| pdb_00002jgy	Download File View File

The crystal structure of human orotidine-5'-decarboxylase domain of human uridine monophosphate synthetase (UMPS)

Moche, M., Ogg, D., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Karlberg, T., Kosinska, U., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Uppenberg, J., Upsten, M., Thorsell, A.G., van den Berg, S., Weigelt, J., Nordlund, P., Structural Genomics Consortium (SGC)

To be published

Released	2007-03-06
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Homo sapiens
Macromolecule	UMP SYNTHASE (protein)

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2JI4 \| pdb_00002ji4	Download File View File

Human phosphoribosylpyrophosphate synthetase - associated protein 41 (PAP41)

Moche, M., Lehtio, L., Arrowsmith, C., Berglund, H., Busam, R., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Holmberg-Schiavone, L., Johansson, I., Karlberg, T., Kotenyova, T., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Nordlund, P.

To be published

Released	2007-03-06
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Homo sapiens
Macromolecule	PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE-ASSOCIATED PROTEIN 2 (protein)
Unique Ligands	CL

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2JIS \| pdb_00002jis	Download File View File

Human cysteine sulfinic acid decarboxylase (CSAD) in complex with PLP.

Collins, R., Moche, M., Arrowsmith, C., Berglund, H., Busam, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Johansson, I., Kallas, A., Karlberg, T., Kotenyova, T., Lehtio, L., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Tresaugues, L., van den Berg, S., Weigelt, J., Welin, M., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

To be published

Released	2007-08-28
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Homo sapiens
Macromolecule	CYSTEINE SULFINIC ACID DECARBOXYLASE (protein)
Unique Ligands	NO3, PLP

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2NMP \| pdb_00002nmp	Download File View File

Crystal structure of human Cystathionine gamma lyase

Karlberg, T., Uppenberg, J., Arrowsmith, C., Berglund, H., Busam, R.D., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Hogbom, M., Johansson, I., Kotenyova, T., Magnusdottir, A., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., van-den-Berg, S., Wallden, K., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2009) J Biological Chem 284: 3076-3085

Released	2006-11-07
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	Cystathionine gamma-lyase (protein)
Unique Ligands	PLP

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2NZ2 \| pdb_00002nz2	Download File View File

Crystal structure of human argininosuccinate synthase in complex with aspartate and citrulline

Karlberg, T., Uppenberg, J., Arrowsmith, C., Berglund, H., Busam, R.D., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Hogbom, M., Johansson, I., Kotenyova, T., Magnusdottir, A., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2008) Acta Crystallogr D Biol Crystallogr 64: 279-286

Released	2006-12-05
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Argininosuccinate synthase (protein)
Unique Ligands	ASP, CIR, NA

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2O7P \| pdb_00002o7p	Download File View File

The crystal structure of RibD from Escherichia coli in complex with the oxidised NADP+ cofactor in the active site of the reductase domain

Moche, M., Stenmark, P., Gurmu, D., Nordlund, P., Structural Proteomics in Europe (SPINE)

(2007) J Mol Biology 373: 48-64

Released	2007-02-13
Method	X-RAY DIFFRACTION 3 Å
Organisms	Escherichia coli K-12
Macromolecule	Riboflavin biosynthesis protein ribD (protein)
Unique Ligands	NAP

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2OBC \| pdb_00002obc	Download File View File

The crystal structure of RibD from Escherichia coli in complex with a substrate analogue, ribose 5-phosphate (beta form), bound to the active site of the reductase domain

Moche, M., Stenmark, P., Gurmu, D., Nordlund, P., Structural Proteomics in Europe (SPINE)

(2007) J Mol Biology 373: 48-64

Released	2007-02-13
Method	X-RAY DIFFRACTION 3 Å
Organisms	Escherichia coli K-12
Macromolecule	Riboflavin biosynthesis protein ribD (protein)
Unique Ligands	RP5

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2ODT \| pdb_00002odt	Download File View File

Structure of human Inositol 1,3,4-trisphosphate 5/6-kinase

Busam, R.D., Arrowsmith, C., Berglund, H., Collins, R., Edwards, A., Ericsson, U.B., Flodin, S., Flores, A., Hammarstrom, M., Holmberg, S.L., Johansson, I., Karlberg, T., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Ogg, D., Sagemark, J., Sundstrom, M., Uppenberg, J., Van Den Berg, S., Weigelt, J., Persson, C., Thorsell, A.G., Hallberg, B.M., Structural Genomics Consortium (SGC)

To be published

Released	2007-02-13
Method	X-RAY DIFFRACTION 2.01 Å
Organisms	Homo sapiens
Macromolecule	Inositol-tetrakisphosphate 1-kinase (protein)

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2OJW \| pdb_00002ojw	Download File View File

Crystal structure of human glutamine synthetase in complex with ADP and phosphate

Karlberg, T., Uppenberg, J., Arrowsmith, C., Berglund, H., Busam, R.D., Collins, R., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Hogbom, M., Johansson, I., Kotenyova, T., Moche, M., Nilsson, M.E., Nordlund, P., Nyman, T., Ogg, D., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Wallden, K., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2008) J Mol Biology 375: 217-228

Released	2007-03-13
Method	X-RAY DIFFRACTION 2.05 Å
Organisms	Homo sapiens
Macromolecule	Glutamine synthetase (protein)
Unique Ligands	ADP, CL, GOL, MN, PO4

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2OXC \| pdb_00002oxc	Download File View File

Human DEAD-box RNA helicase DDX20, DEAD domain in complex with ADP

Karlberg, T., Ogg, D., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Hogbom, M., Johansson, I., Kotenyova, T., Lehtio, L., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

To be published

Released	2007-02-27
Method	X-RAY DIFFRACTION 1.3 Å
Organisms	Homo sapiens
Macromolecule	Probable ATP-dependent RNA helicase DDX20 (protein)
Unique Ligands	ADP

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2P6N \| pdb_00002p6n	Download File View File

Human DEAD-box RNA helicase DDX41, helicase domain

Karlberg, T., Ogg, D., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A., Flodin, S., Flores, A., Graslund, S., Hallberg, B.M., Hammarstrom, M., Johansson, I., Kotenyova, T., Lehtio, L., Moche, M., Nordlund, P., Nyman, T., Persson, C., Sagemark, J., Stenmark, P., Sundstrom, M., Thorsell, A.G., Van Den Berg, S., Weigelt, J., Holmberg-Schiavone, L., Structural Genomics Consortium (SGC)

(2010) PLoS One 5: 12791-12791

Released	2007-04-03
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens
Macromolecule	ATP-dependent RNA helicase DDX41 (protein)

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Structure Determination Methodology

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Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1B3N | pdb_00001b3n

1E5M | pdb_00001e5m

1OQ4 | pdb_00001oq4

1OQ7 | pdb_00001oq7

1OQ9 | pdb_00001oq9

1OQB | pdb_00001oqb

2G6V | pdb_00002g6v

2J2F | pdb_00002j2f

2J8Q | pdb_00002j8q

2J91 | pdb_00002j91

2JAK | pdb_00002jak

2JBH | pdb_00002jbh

2JCN | pdb_00002jcn

2JEO | pdb_00002jeo

2JGY | pdb_00002jgy

2JI4 | pdb_00002ji4

2JIS | pdb_00002jis

2NMP | pdb_00002nmp

2NZ2 | pdb_00002nz2

2O7P | pdb_00002o7p

2OBC | pdb_00002obc

2ODT | pdb_00002odt

2OJW | pdb_00002ojw

2OXC | pdb_00002oxc

2P6N | pdb_00002p6n