RP5

5-O-phosphono-beta-D-ribofuranose

Created:	2003-04-30
Last modified:	2020-07-17

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16 entries where RP5 is found as a standalone ligand1 entries where RP5 is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	25
Chiral Atom Count	4
Bond Count	25
Aromatic Bond Count	0

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Chemical Component Summary
Name	5-O-phosphono-beta-D-ribofuranose
Synonyms	[(2R,3S,4S,5R)-3,4,5-TRIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN PHOSPHATE; 5-O-phosphono-beta-D-ribose; 5-O-phosphono-D-ribose; 5-O-phosphono-ribose
Systematic Name (OpenEye OEToolkits)	[(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl dihydrogen phosphate
Formula	C₅ H₁₁ O₈ P
Molecular Weight	230.11
Type	D-SACCHARIDE, BETA LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	12.01	O=P(O)(O)OCC1OC(O)C(O)C1O
SMILES	CACTVS	3.370	O[CH]1O[CH](CO[P](O)(O)=O)[CH](O)[CH]1O
SMILES	OpenEye OEToolkits	1.7.0	C(C1C(C(C(O1)O)O)O)OP(=O)(O)O
Canonical SMILES	CACTVS	3.370	O[C@@H]1O[C@H](CO[P](O)(O)=O)[C@@H](O)[C@H]1O
Canonical SMILES	OpenEye OEToolkits	1.7.0	C([C@@H]1[C@H]([C@H]([C@@H](O1)O)O)O)OP(=O)(O)O
InChI	InChI	1.03	InChI=1S/C5H11O8P/c6-3-2(1-12-14(9,10)11)13-5(8)4(3)7/h2-8H,1H2,(H2,9,10,11)/t2-,3-,4-,5-/m1/s1
InChIKey	InChI	1.03	KTVPXOYAKDPRHY-TXICZTDVSA-N

Drug Info: DrugBank

DrugBank ID	DB04352
Name	beta-D-Ribose-5-phosphate
Groups	experimental
Synonyms	β-D-ribofuranose 5-phosphate 5-O-phosphono-beta-D-ribofuranose beta-D-Ribose-5-phosphate 5-O-phosphono-β-D-ribofuranose
CAS number	34980-66-0

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
D-ribose pyranase	MKKHGILNSHLAKILADLGHTDKIVIADAGLPVPDGVLKIDLSLKPGLPA...	unknown
ADP-ribose pyrophosphatase, mitochondrial	MAGRLLGKALAAVSLSLALASVTIRSSRCRGIQAFRNSFSSSWFHLNTNV...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682