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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Ghirlando, R."

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Search Summary

This query matches 34 Structures.

Refinements

Structure Determination Methodology

experimental (34)

Scientific Name of Source Organism

	Homo sapiens (12)
	Saccharomyces cerevisiae (4)
	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) (3)
	Bos taurus (2)
	Escherichia coli (2)
	Escherichia coli K-12 (2)
	Haemophilus influenzae (2)
	Helicobacter pylori (2)
	Mus musculus (2)
	Rattus norvegicus (2)

More...

Taxonomy

	Eukaryota (21)
	Bacteria (9)
	Riboviria (4)
	Eukaryota (eukaryotes) (1)

Experimental Method

	X-RAY DIFFRACTION (24)
	SOLUTION NMR (10)
	SOLUTION SCATTERING (3)

Polymer Entity Type

	Protein (34)
	DNA (9)
	RNA (4)

Refinement Resolution (Å)

	1.5 - 2.0 (1)
	2.0 - 2.5 (14)
	2.5 - 3.0 (6)
	3.0 - 3.5 (1)
	3.5 - 4.0 (1)
	> 4.5 (1)

Release Date

	2000 - 2004 (6)
	2005 - 2009 (16)
	2010 - 2014 (8)
	2015 - 2019 (4)

Enzyme Classification Name

	Transferases (5)
	Hydrolases (6)

Membrane Protein Annotation

	MemProtMD (1)
	OPM (1)

Symmetry Type

	Asymmetric (21)
	Cyclic (13)
	Dihedral (2)

SCOP Classification

	Alpha and beta proteins (a+b) (9)
	All alpha proteins (10)
	Alpha and beta proteins (a/b) (5)
	Artifacts (3)
	All beta proteins (2)

AllSelected

1 to 25 of 34 Structures

Page 1 of 2

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1IB1 \| pdb_00001ib1	Download File View File

CRYSTAL STRUCTURE OF THE 14-3-3 ZETA:SEROTONIN N-ACETYLTRANSFERASE COMPLEX

Obsil, T., Ghirlando, R., Klein, D.C., Ganguly, S., Dyda, F.

(2001) Cell 105: 257-267

Released	2001-05-02
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Homo sapiens Ovis aries
Macromolecule	14-3-3 ZETA ISOFORM (protein) SEROTONIN N-ACETYLTRANSFERASE (protein)
Unique Ligands	COT

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1MN3 \| pdb_00001mn3	Download File View File

Cue domain of yeast Vps9p

Prag, G., Misra, S., Jones, E., Ghirlando, R., Davies, B.A., Horazdovsky, B.F., Hurley, J.H.

(2003) Cell 113: 609-620

Released	2003-06-10
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Vacuolar protein sorting-associated protein VPS9 (protein)

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1P3Q \| pdb_00001p3q	Download File View File

Mechanism of Ubiquitin Recognition by the CUE Domain of VPS9

Prag, G., Misra, S., Jones, E.A., Ghirlando, R., Davies, B.A., Horazdovsky, B.F., Hurley, J.H.

(2003) Cell 113: 609-620

Released	2003-06-24
Method	X-RAY DIFFRACTION 1.7 Å
Organisms	Bos taurus Saccharomyces cerevisiae
Macromolecule	Ubiquitin (protein) Vacuolar protein sorting-associated protein VPS9 (protein)

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1RPY \| pdb_00001rpy	Download File View File

CRYSTAL STRUCTURE OF THE DIMERIC SH2 DOMAIN OF APS

Hu, J., Liu, J., Ghirlando, R., Saltiel, A.R., Hubbard, S.R.

(2003) Mol Cell 12: 1379-1389

Released	2003-12-23
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Rattus norvegicus
Macromolecule	adaptor protein APS (protein)
Unique Ligands	SO4

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1RQQ \| pdb_00001rqq	Download File View File

Crystal Structure of the Insulin Receptor Kinase in Complex with the SH2 Domain of APS

Hu, J., Liu, J., Ghirlando, R., Saltiel, A.R., Hubbard, S.R.

(2003) Mol Cell 12: 1379-1389

Released	2003-12-30
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Homo sapiens Rattus norvegicus
Macromolecule	BISUBSTRATE INHIBITOR (protein) Insulin receptor (protein) adaptor protein APS (protein)
Unique Ligands	112, MN

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1X9Z \| pdb_00001x9z	Download File View File

Crystal structure of the MutL C-terminal domain

Guarne, A., Ramon-Maiques, S., Wolff, E.M., Ghirlando, R., Hu, X., Miller, J.H., Yang, W.

(2004) EMBO J 23: 4134-4145

Released	2004-10-26
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Escherichia coli
Macromolecule	DNA mismatch repair protein mutL (protein)
Unique Ligands	CL, GOL, IPA, NA

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1XRX \| pdb_00001xrx	Download File View File

Crystal structure of a DNA-binding protein

Guarne, A., Brendler, T., Zhao, Q., Ghirlando, R., Austin, S., Yang, W.

(2005) EMBO J 24: 1502-1511

Released	2005-05-10
Method	X-RAY DIFFRACTION 2.15 Å
Organisms	Escherichia coli
Macromolecule	SeqA protein (protein)
Unique Ligands	CA

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1YM7 \| pdb_00001ym7	Download File View File

G Protein-Coupled Receptor Kinase 2 (GRK2)

Lodowski, D.T., Barnhill, J.F., Pyskadlo, R.M., Ghirlando, R., Sterne-Marr, R., Tesmer, J.J.G.

(2005) Biochemistry 44: 6958-6970

Released	2005-07-05
Method	X-RAY DIFFRACTION 4.5 Å
Organisms	Bos taurus
Macromolecule	Beta-adrenergic receptor kinase 1 (protein)

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2A6M \| pdb_00002a6m	Download File View File

Crystal Structure of the ISHp608 Transposase

Ronning, D.R., Guynet, C., Ton-Hoang, B., Perez, Z.N., Ghirlando, R., Chandler, M., Dyda, F.

(2005) Mol Cell 20: 143-154

Released	2005-10-25
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Helicobacter pylori
Macromolecule	ISHp608 transposase (protein)

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2A6O \| pdb_00002a6o	Download File View File

Crystal Structure of the ISHp608 Transposase in Complex with Stem-loop DNA

Ronning, D.R., Guynet, C., Ton-Hoang, B., Perez, Z.N., Ghirlando, R., Chandler, M., Dyda, F.

(2005) Mol Cell 20: 143-154

Released	2005-10-25
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Helicobacter pylori
Macromolecule	ISHp608 Transposase (protein) 5'-D(CPCPCPCPTPAPGPCPTPTPTPAPGPCPTPAPTPGPGPGPGPA)-3' (nucleic acid)

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2AOQ \| pdb_00002aoq	Download File View File

Crystal structure of MutH-unmethylated DNA complex

Lee, J.Y., Chang, J., Joseph, N., Ghirlando, R., Rao, D.N., Yang, W.

(2005) Mol Cell 20: 155-166

Released	2005-10-11
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Haemophilus influenzae
Macromolecule	DNA mismatch repair protein mutH (protein) 5'-D(GPCPAPTPGPAPTPCPAPTPGPC)-3' (nucleic acid)
Unique Ligands	CA

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2AOR \| pdb_00002aor	Download File View File

Crystal structure of MutH-hemimethylated DNA complex

Lee, J.Y., Chang, J., Joseph, N., Ghirlando, R., Rao, D.N., Yang, W.

(2005) Mol Cell 20: 155-166

Released	2005-10-11
Method	X-RAY DIFFRACTION 2 Å
Organisms	Haemophilus influenzae
Macromolecule	DNA mismatch repair protein mutH (protein) 5'-D(CPAPGPGP(6MA)PTPCPCPAPAPGPCPTPTPGPGPAPTPCPCPTPG)-3' (nucleic acid)
Unique Ligands	CA

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2BW3 \| pdb_00002bw3	Download File View File

Three-dimensional structure of the Hermes DNA transposase

Hickman, A.B., Perez, Z.N., Zhou, L., Musingarimi, P., Ghirlando, R., Hinshaw, J.E., Craig, N.L., Dyda, F.

(2005) Nat Struct Mol Biol 12: 715

Released	2005-07-28
Method	X-RAY DIFFRACTION 2 Å
Organisms	Musca domestica
Macromolecule	TRANSPOSASE (protein)

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2BZF \| pdb_00002bzf	Download File View File

Structural basis for DNA bridging by barrier-to-autointegration factor (BAF)

Bradley, C.M., Ronning, D.R., Ghirlando, R., Craigie, R., Dyda, F.

(2005) Nat Struct Mol Biol 12: 935

Released	2005-09-15
Method	X-RAY DIFFRACTION 2.87 Å
Organisms	Homo sapiens
Macromolecule	BARRIER-TO-AUTOINTEGRATION FACTOR (protein) 5'-D(CPCPTPCPCPAPCP)-3' (nucleic acid) 5'-D(GPTPGPGPAPGPGP)-3' (nucleic acid)

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2KDT \| pdb_00002kdt	Download File View File

PC1/3 DCSG sorting domain structure in DPC

Dikeakos, J.D., Di Lello, P., Lacombe, M.J., Ghirlando, R., Legault, P., Reudelhuber, T.L., Omichinski, J.G.

(2009) Proc Natl Acad Sci U S A 106: 7408-7413

Released	2009-04-07
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Neuroendocrine convertase 1 (protein)

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2KE3 \| pdb_00002ke3	Download File View File

PC1/3 DCSG sorting domain in CHAPS

Dikeakos, J.D., Di Lello, P., Lacombe, M.J., Ghirlando, R., Legault, P., Reudelhuber, T.L., Omichinski, J.G.

(2009) Proc Natl Acad Sci U S A 106: 7408-7413

Released	2009-04-14
Method	SOLUTION NMR
Organisms	Mus musculus
Macromolecule	Neuroendocrine convertase 1 (protein)

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2L5A \| pdb_00002l5a	Download File View File

Structural basis for recognition of centromere specific histone H3 variant by nonhistone Scm3

Zhou, Z., Feng, H., Zhou, B., Ghirlando, R., Hu, K., Zwolak, A., Jenkins, L., Xiao, H., Tjandra, N., Wu, C., Bai, Y.

(2011) Nature 472: 234-237

Released	2011-03-16
Method	SOLUTION NMR
Organisms	Saccharomyces cerevisiae
Macromolecule	Histone H3-like centromeric protein CSE4, Protein SCM3, Histone H4 (protein)

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2LY8 \| pdb_00002ly8	Download File View File

The budding yeast chaperone Scm3 recognizes the partially unfolded dimer of the centromere-specific Cse4/H4 histone variant

Hong, J., Feng, H., Zhou, Z., Ghirlando, R., Bai, Y.

(2013) J Mol Biology 425: 536-545

Released	2012-12-12
Method	SOLUTION NMR
Organisms	Saccharomyces cerevisiae
Macromolecule	Budding yeast chaperone Scm3 (protein)

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2M8L \| pdb_00002m8l	Download File View File

HIV capsid dimer structure

Deshmukh, L., Schwieters, C.D., Grishaev, A., Clore, G., Ghirlando, R.

(2013) J Am Chem Soc 135: 16133-16147

Released	2013-11-20
Method	SOLUTION NMR SOLUTION SCATTERING
Organisms	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Macromolecule	Capsid protein p24 (protein)

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2M8N \| pdb_00002m8n	Download File View File

HIV-1 capsid monomer structure

Deshmukh, L., Schwieters, C.D., Grishaev, A., Clore, G., Ghirlando, R.

(2013) J Am Chem Soc 135: 16133-16147

Released	2013-11-20
Method	SOLUTION NMR SOLUTION SCATTERING
Organisms	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Macromolecule	Capsid protein p24 (protein)

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2M8P \| pdb_00002m8p	Download File View File

The structure of the W184AM185A mutant of the HIV-1 capsid protein

Deshmukh, L., Schwieters, C.D., Grishaev, A., Clore, G., Ghirlando, R.

(2013) J Am Chem Soc 135: 16133-16147

Released	2013-11-20
Method	SOLUTION NMR SOLUTION SCATTERING
Organisms	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)
Macromolecule	Capsid protein p24 (protein)

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2QK9 \| pdb_00002qk9	Download File View File

Human RNase H catalytic domain mutant D210N in complex with 18-mer RNA/DNA hybrid

Nowotny, M., Gaidamakov, S.A., Ghirlando, R., Cerritelli, S.M., Crouch, R.J., Yang, W.

(2007) Mol Cell 28: 264-276

Released	2007-11-13
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Homo sapiens
Macromolecule	Ribonuclease H1 (protein) 5'-D(GPGPAPAPTPCPAPGPGPTPGPTPCPGPCPAPCPT)-3' (nucleic acid) 5'-R(APGPUPGPCPGPAPCPAPCPCPUPGPAPUPUPCPC)-3' (nucleic acid)
Unique Ligands	16D, FLC, GOL, NA, SO4

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2QKB \| pdb_00002qkb	Download File View File

Human RNase H catalytic domain mutant D210N in complex with 20-mer RNA/DNA hybrid

Nowotny, M., Gaidamakov, S.A., Ghirlando, R., Cerritelli, S.M., Crouch, R.J., Yang, W.

(2007) Mol Cell 28: 264-276

Released	2007-11-13
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Homo sapiens
Macromolecule	Ribonuclease H1 (protein) 5'-D(DGPDGPDAPDAPDTPDCPDAPDGPDGPDTPDGPDTPDCPDGPDCPDAPDCPDTPDCPDT)-3' (nucleic acid) 5'-R(GPGPAPGPUPGPCPGPAPCPAPCPCPUPGPAPUPUPCPC)-3') (nucleic acid)
Unique Ligands	EDO, SO4

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2QKK \| pdb_00002qkk	Download File View File

Human RNase H catalytic domain mutant D210N in complex with 14-mer RNA/DNA hybrid

Nowotny, M., Gaidamakov, S.A., Ghirlando, R., Cerritelli, S.M., Crouch, R.J., Yang, W.

(2007) Mol Cell 28: 264-276

Released	2007-11-13
Method	X-RAY DIFFRACTION 3.2 Å
Organisms	Homo sapiens
Macromolecule	Ribonuclease H1 (protein) 5'-D(GPGPAPAPTPCPAPGPGPTPGPTPCPG)-3' (nucleic acid) 5'-R(CPGPAPCPAPCPCPUPGPAPUPUPCPC)-3' (nucleic acid)
Unique Ligands	CA, CL, MES, TRS