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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Structure Author = "Conti, E."

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Search Summary

This query matches 161 Structures.

Refinements

Structure Determination Methodology

experimental (161)

Scientific Name of Source Organism

	Homo sapiens (68)
	Saccharomyces cerevisiae (28)
	Saccharomyces cerevisiae S288C (27)
	synthetic construct (10)
	Saccharolobus solfataricus (9)
	Drosophila melanogaster (6)
	Caenorhabditis elegans (5)
	Mus musculus (5)
	Pyrococcus furiosus DSM 3638 (5)
	Cricket paralysis virus (4)

More...

Taxonomy

	Eukaryota (141)
	Archaea (16)
	other sequences (10)
	Bacteria (4)
	Riboviria (4)
	Duplodnaviria (1)

Experimental Method

	X-RAY DIFFRACTION (127)
	ELECTRON MICROSCOPY (34)

Polymer Entity Type

	Protein (161)
	RNA (34)

Refinement Resolution (Å)

	1.0 - 1.5 (1)
	1.5 - 2.0 (17)
	2.0 - 2.5 (40)
	2.5 - 3.0 (42)
	3.0 - 3.5 (38)
	3.5 - 4.0 (14)
	4.0 - 4.5 (2)
	> 4.5 (7)

Release Date

	1990 - 1994 (2)
	1995 - 1999 (9)
	2000 - 2004 (13)
	2005 - 2009 (26)
	2010 - 2014 (51)
	2015 - 2019 (27)
	2020 - 2024 (33)

Enzyme Classification Name

	Hydrolases (82)
	Transferases (20)
	Isomerases (4)
	Lyases (2)
	Oxidoreductases (2)
	Ligases (1)

Symmetry Type

	Asymmetric (136)
	Cyclic (22)
	Dihedral (4)

SCOP Classification

	Alpha and beta proteins (a+b) (29)
	Alpha and beta proteins (a/b) (18)
	All beta proteins (10)
	All alpha proteins (11)
	Artifacts (13)
	Multi-domain proteins (alpha and beta) (3)
	Small proteins (3)

AllSelected

1 to 25 of 161 Structures

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1A0C \| pdb_00001a0c	Download File View File

XYLOSE ISOMERASE FROM THERMOANAEROBACTERIUM THERMOSULFURIGENES

Gallay, O., Chopra, R., Conti, E., Brick, P., Blow, D.

To be published

Released	1998-06-03
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Thermoanaerobacterium thermosulfurigenes
Macromolecule	XYLOSE ISOMERASE (protein)
Unique Ligands	CO

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1A0D \| pdb_00001a0d	Download File View File

XYLOSE ISOMERASE FROM BACILLUS STEAROTHERMOPHILUS

Gallay, O., Chopra, R., Conti, E., Brick, P., Blow, D.

To be published

Released	1998-06-03
Method	X-RAY DIFFRACTION 3 Å
Organisms	Geobacillus stearothermophilus
Macromolecule	XYLOSE ISOMERASE (protein)
Unique Ligands	MN

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1A0E \| pdb_00001a0e	Download File View File

XYLOSE ISOMERASE FROM THERMOTOGA NEAPOLITANA

Gallay, O., Chopra, R., Conti, E., Brick, P., Blow, D.

To be published

Released	1998-06-03
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Thermotoga neapolitana
Macromolecule	XYLOSE ISOMERASE (protein)
Unique Ligands	CO

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1AMU \| pdb_00001amu	Download File View File

PHENYLALANINE ACTIVATING DOMAIN OF GRAMICIDIN SYNTHETASE 1 IN A COMPLEX WITH AMP AND PHENYLALANINE

Conti, E., Stachelhaus, T., Marahiel, M.A., Brick, P.

(1997) EMBO J 16: 4174-4183

Released	1998-07-01
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Brevibacillus brevis
Macromolecule	GRAMICIDIN SYNTHETASE 1 (protein)
Unique Ligands	AMP, MG, PHE, SO4

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1BA3 \| pdb_00001ba3	Download File View File

FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM

Franks, N.P., Jenkins, A., Conti, E., Lieb, W.R., Brick, P.

(1998) Biophys J 75: 2205-2211

Released	1998-11-11
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Photinus pyralis
Macromolecule	LUCIFERASE (protein)
Unique Ligands	MBR

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1BCU \| pdb_00001bcu	Download File View File

ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND PROFLAVIN

Conti, E., Rivetti, C., Wonacott, A., Brick, P.

(1998) FEBS Lett 425: 229-233

Released	1998-10-14
Method	X-RAY DIFFRACTION 2 Å
Organisms	Hirudo medicinalis Homo sapiens
Macromolecule	ALPHA-THROMBIN (protein) HIRUGEN (protein)
Unique Ligands	PRL

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1BK5 \| pdb_00001bk5	Download File View File

KARYOPHERIN ALPHA FROM SACCHAROMYCES CEREVISIAE

Conti, E., Uy, M., Leighton, L., Blobel, G., Kuriyan, J.

(1998) Cell 94: 193-204

Released	1999-01-06
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	KARYOPHERIN ALPHA (protein)
Unique Ligands	CO

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1BK6 \| pdb_00001bk6	Download File View File

KARYOPHERIN ALPHA (YEAST) + SV40 T ANTIGEN NLS

Conti, E., Uy, M., Leighton, L., Blobel, G., Kuriyan, J.

(1998) Cell 94: 193-204

Released	1999-01-13
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	KARYOPHERIN ALPHA (protein) LARGE T ANTIGEN (protein)

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1EE4 \| pdb_00001ee4	Download File View File

CRYSTAL STRUCTURE OF YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A C-MYC NLS PEPTIDE

Conti, E.

(2000) Structure 8: 329-338

Released	2000-03-29
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens Saccharomyces cerevisiae
Macromolecule	KARYOPHERIN ALPHA (protein) MYC PROTO-ONCOGENE PROTEIN (protein)

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1EE5 \| pdb_00001ee5	Download File View File

YEAST KARYOPHERIN (IMPORTIN) ALPHA IN A COMPLEX WITH A NUCLEOPLASMIN NLS PEPTIDE

Conti, E.

(2000) Structure 8: 329-338

Released	2000-03-29
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Saccharomyces cerevisiae Xenopus laevis
Macromolecule	KARYOPHERIN ALPHA (protein) NUCLEOPLASMIN (protein)

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1FO1 \| pdb_00001fo1	Download File View File

CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE MRNA EXPORT FACTOR TAP

Liker, E., Fernandez, E., Izaurralde, E., Conti, E.

(2000) EMBO J 19: 5587-5598

Released	2000-11-03
Method	X-RAY DIFFRACTION 2.9 Å
Organisms	Homo sapiens
Macromolecule	NUCLEAR RNA EXPORT FACTOR 1 (protein)

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1FT8 \| pdb_00001ft8	Download File View File

CRYSTAL STRUCTURE OF THE RNA-BINDING DOMAIN OF THE MRNA EXPORT FACTOR TAP

Liker, E., Fernandez, E., Izaurralde, E., Conti, E.

(2000) EMBO J 19: 5587-5598

Released	2000-12-11
Method	X-RAY DIFFRACTION 3.15 Å
Organisms	Homo sapiens
Macromolecule	TIP ASSOCIATING PROTEIN (protein)

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1HL6 \| pdb_00001hl6	Download File View File

A novel mode of RBD-protein recognition in the Y14-mago complex

Fribourg, S., Gatfield, D., Yao, W., Izaurralde, E., Conti, E.

(2003) Nat Struct Biol 10: 433

Released	2003-05-08
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Drosophila melanogaster
Macromolecule	CG8781 PROTEIN (protein) MAGO NASHI PROTEIN (protein)

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1JKG \| pdb_00001jkg	Download File View File

Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA nuclear export factor

Fribourg, S., Braun, I.C., Izaurralde, E., Conti, E.

(2001) Mol Cell 8: 645-656

Released	2001-10-17
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens
Macromolecule	TAP (protein) p15 (protein)

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1JN5 \| pdb_00001jn5	Download File View File

Structural basis for the recognition of a nucleoporin FG-repeat by the NTF2-like domain of TAP-p15 mRNA export factor

Fribourg, S., Braun, I.C., Izaurralde, E., Conti, E.

(2001) Mol Cell 8: 645-656

Released	2001-10-17
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens
Macromolecule	FG-repeat (protein) TAP (protein) p15 (protein)

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1LCI \| pdb_00001lci	Download File View File

FIREFLY LUCIFERASE

Conti, E., Franks, N.P., Brick, P.

(1996) Structure 4: 287-298

Released	1997-03-26
Method	X-RAY DIFFRACTION 2 Å
Organisms	Photinus pyralis
Macromolecule	LUCIFERASE (protein)

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1OF5 \| pdb_00001of5	Download File View File

Crystal structure of Mex67-Mtr2

Fribourg, S., Conti, E.

(2003) EMBO Rep 4: 699-703

Released	2003-07-03
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	MRNA EXPORT FACTOR MEX67 (protein) MRNA TRANSPORT REGULATOR MTR2 (protein)
Unique Ligands	HG

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1OL5 \| pdb_00001ol5	Download File View File

Structure of Aurora-A 122-403, phosphorylated on Thr287, Thr288 and bound to TPX2 1-43

Bayliss, R., Conti, E.

(2003) Mol Cell 12: 851

Released	2003-10-30
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens
Macromolecule	RESTRICTED EXPRESSION PROLIFERATION ASSOCIATED PROTEIN 100 (protein) SERINE/THREONINE KINASE 6 (protein)
Unique Ligands	ADP, MG, SO4

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1OL6 \| pdb_00001ol6	Download File View File

Structure of unphosphorylated D274N mutant of Aurora-A

Bayliss, R., Conti, E.

(2003) Mol Cell 12: 851

Released	2003-10-30
Method	X-RAY DIFFRACTION 3 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE KINASE 6 (protein)
Unique Ligands	ATP

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1OL7 \| pdb_00001ol7	Download File View File

Structure of Human Aurora-A 122-403 phosphorylated on Thr287, Thr288

Bayliss, R., Conti, E.

(2003) Mol Cell 12: 851

Released	2003-10-30
Method	X-RAY DIFFRACTION 2.75 Å
Organisms	Homo sapiens
Macromolecule	SERINE/THREONINE KINASE 6 (protein)
Unique Ligands	ADP, MG

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1RK8 \| pdb_00001rk8	Download File View File

Structure of the cytosolic protein PYM bound to the Mago-Y14 core of the exon junction complex

Bono, F., Ebert, J., Guettler, T., Izaurralde, E., Conti, E.

(2004) EMBO Rep 5: 304-310

Released	2004-04-13
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Drosophila melanogaster
Macromolecule	CG8781-PA protein (protein) Mago nashi protein (protein) Within the bgcn gene intron protein (protein)
Unique Ligands	CA

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1W3B \| pdb_00001w3b	Download File View File

The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.

Jinek, M., Rehwinkel, J., Lazarus, B.D., Izaurralde, E., Hanover, J.A., Conti, E.

(2004) Nat Struct Mol Biol 11: 1001

Released	2004-09-09
Method	X-RAY DIFFRACTION 2.85 Å
Organisms	Homo sapiens
Macromolecule	UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 (protein)
Unique Ligands	CA

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1YA0 \| pdb_00001ya0	Download File View File

Crystal structure of the N-terminal domain of human SMG7

Fukuhara, N., Ebert, J., Unterholzner, L., Lindner, D., Izaurralde, E., Conti, E.

(2005) Mol Cell 17: 537-547

Released	2005-03-15
Method	X-RAY DIFFRACTION 2.55 Å
Organisms	Homo sapiens
Macromolecule	SMG-7 transcript variant 2 (protein)
Unique Ligands	SO4

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1Z3H \| pdb_00001z3h	Download File View File

The exportin Cse1 in its cargo-free, cytoplasmic state

Cook, A., Fernandez, E., Lindner, D., Ebert, J., Schlenstedt, G., Conti, E.

(2005) Mol Cell 18: 355-367

Released	2005-05-10
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Saccharomyces cerevisiae
Macromolecule	Importin alpha re-exporter (protein)
Unique Ligands	MG

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2BR2 \| pdb_00002br2	Download File View File

RNase PH core of the archaeal exosome

lorentzen, E., Fribourg, S., Conti, E.

(2005) Nat Struct Mol Biol 12: 575

Released	2005-06-06
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Saccharolobus solfataricus
Macromolecule	EXOSOME COMPLEX EXONUCLEASE 1 (protein) EXOSOME COMPLEX EXONUCLEASE 2 (protein)
Unique Ligands	CL

1 to 25 of 161 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Symmetry Type

SCOP Classification

1A0C | pdb_00001a0c

1A0D | pdb_00001a0d

1A0E | pdb_00001a0e

1AMU | pdb_00001amu

1BA3 | pdb_00001ba3

1BCU | pdb_00001bcu

1BK5 | pdb_00001bk5

1BK6 | pdb_00001bk6

1EE4 | pdb_00001ee4

1EE5 | pdb_00001ee5

1FO1 | pdb_00001fo1

1FT8 | pdb_00001ft8

1HL6 | pdb_00001hl6

1JKG | pdb_00001jkg

1JN5 | pdb_00001jn5

1LCI | pdb_00001lci

1OF5 | pdb_00001of5

1OL5 | pdb_00001ol5

1OL6 | pdb_00001ol6

1OL7 | pdb_00001ol7

1RK8 | pdb_00001rk8

1W3B | pdb_00001w3b

1YA0 | pdb_00001ya0

1Z3H | pdb_00001z3h

2BR2 | pdb_00002br2