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Glycine receptor subunit alpha-1

UniProtKB accession:  P23415
Grouped By:  Matching UniProtKB accession
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Polymer Entities matching query 1
Go to UniProtKB:  P23415
UniProtKB description:  Subunit of heteromeric glycine-gated chloride channels (PubMed:14551753, PubMed:23994010, PubMed:25730860, PubMed:37821459). Plays an important role in the down-regulation of neuronal excitability (PubMed:8298642, PubMed:9009272). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488). Channel activity is potentiated by ethanol (PubMed:25973519). Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol (By similarity).
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Structure Features
Determination Methodology


Sequence Features
Number of Source Taxonomies


Experimental Features
Experimental Method
Resolution


Organisms
Organism
Taxonomy


Protein Domains
ECOD Domain
PFAM Domain
InterPro Domain


Function
GO Cellular Component