❮
Member 1 of 360
❯
Carboxypeptidase Y
UniProtKB accession: P00729
Grouped By: Matching UniProtKB accession
Group Content:
Polymer Entities matching query 360
Go to UniProtKB: P00729
UniProtKB description: Vacuolar serine-type carboxypeptidase involved in degradation of small peptides (PubMed:8679540). Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (PubMed:8679540). Also plays a role in breakdown of the autophagic body and the autophagosome-dependent protein synthesis (PubMed:29514932). Plays a key role in phytochelatin (PC) synthesis from glutathione (GSH) by cleaving the Gly from GSH and form the PC-peptides of the structure (gamma-Glu-Cys)2-Gly (PubMed:17408619). Also involved in resistance to xenobiotics via the degradation of glutathione-S-conjugates (PubMed:19897216).
Group Members:
Query History
❮
1 / 1
❯
[ 112+ ]
Release Date:
Structure Features
Determination Methodology
Sequence Features
Number of Source Taxonomies
Experimental Features
Experimental Method
Resolution
Organisms
Organism
[ 71+ ]
Taxonomy
Protein Domains
SCOP/SCOPe Domain
CATH Domain
ECOD Domain
PFAM Domain
InterPro Domain
Function
Enzyme Classification
GO Molecular Function
[ 1+ ]
GO Biological Process
[ 9+ ]
GO Cellular Component
[ 16+ ]
Disease Association
[ 42+ ]
Phenotype Association
