Ras-related protein M-Ras

UniProtKB accession:  O08989

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UniProtKB description:  Signal transducer in the Ras-MAPK signaling pathway that regulates cell proliferation and survival (By similarity). Core component of the SHOC2-MRAS-PP1c (SMP) holophosphatase complex that regulates the MAPK pathway activation (By similarity). The formation of the SMP complex only occurs when MRAS is GTP-bound (By similarity). The SMP complex specifically dephosphorylates the inhibitory phosphorylation at 'Ser-259' of RAF1 kinase, 'Ser-365' of BRAF kinase and 'Ser-214' of ARAF kinase, stimulating their kinase activities (By similarity).