9E1G

Structure of RyR1 in the primed state in the presence of oxypurinol

External Resource: Annotation


Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
B [auth E]SCOP2B SuperfamilyRotamase-like 8098876 3000622 SCOP2B (2022-06-29)
C [auth H]SCOP2B SuperfamilyRotamase-like 8098876 3000622 SCOP2B (2022-06-29)
D [auth G]SCOP2B SuperfamilyRotamase-like 8098876 3000622 SCOP2B (2022-06-29)
E [auth F]SCOP2B SuperfamilyRotamase-like 8098876 3000622 SCOP2B (2022-06-29)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A,
F [auth B],
G [auth D],
H [auth C]		PF00622SPRY domain (SPRY)SPRY domain- Family
A,
F [auth B],
G [auth D],
H [auth C]		PF08454RyR and IP3R Homology associated (RIH_assoc)RyR and IP3R Homology associated- Repeat
A,
F [auth B],
G [auth D],
H [auth C]		PF02815MIR domain (MIR)MIR domainThe MIR (protein mannosyltransferase, IP3R and RyR) domain is a domain that may have a ligand transferase function [1].Domain
A,
F [auth B],
G [auth D],
H [auth C]		PF21119Ryanodine receptor junctional solenoid repeat (RYDR_Jsol)Ryanodine receptor junctional solenoid repeatThis entry represents a region of the Ryanodine receptor composed of alpha helical ARM repeats [1]. This region has been termed the Junctional solenoid region (Jsol) [1].Domain
A,
F [auth B],
G [auth D],
H [auth C]		PF01365RIH domain (RYDR_ITPR)RIH domain- Repeat
A,
F [auth B],
G [auth D],
H [auth C]		PF00520Ion transport protein (Ion_trans)Ion transport protein- Family
A,
F [auth B],
G [auth D],
H [auth C]		PF02026RyR domain (RyR)RyR domain- Family
B [auth E],
C [auth H],
D [auth G],
E [auth F]		PF00254FKBP-type peptidyl-prolyl cis-trans isomerase (FKBP_C)FKBP-type peptidyl-prolyl cis-trans isomerase- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A,
F [auth B],
G [auth D],
H [auth C]		Ryanodine receptor 1
B [auth E],
C [auth H],
D [auth G],
E [auth F]		Peptidyl-prolyl cis-trans isomerase FKBP1A

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A,
F [auth B],
G [auth D],
H [auth C]		IPR036300Mir domain superfamilyHomologous Superfamily
A,
F [auth B],
G [auth D],
H [auth C]		IPR000699RIH domainDomain
A,
F [auth B],
G [auth D],
H [auth C]		IPR013662RyR/IP3R Homology associated domainDomain
A,
F [auth B],
G [auth D],
H [auth C]		IPR016093MIR motifDomain
A,
F [auth B],
G [auth D],
H [auth C]		IPR013320Concanavalin A-like lectin/glucanase domain superfamilyHomologous Superfamily
A,
F [auth B],
G [auth D],
H [auth C]		IPR003877SPRY domainDomain
A,
F [auth B],
G [auth D],
H [auth C]		IPR001870B30.2/SPRY domainDomain
A,
F [auth B],
G [auth D],
H [auth C]		IPR009460Ryanodine Receptor TM 4-6Domain
A,
F [auth B],
G [auth D],
H [auth C]		IPR015925Ryanodine/Inositol 1,4,5-trisphosphate receptorFamily
A,
F [auth B],
G [auth D],
H [auth C]		IPR048581Ryanodine receptor, junctional solenoid domainDomain
A,
F [auth B],
G [auth D],
H [auth C]		IPR035910RyR/IP3 receptor binding core, RIH domain superfamilyHomologous Superfamily
A,
F [auth B],
G [auth D],
H [auth C]		IPR003032Ryanodine receptor RyrDomain
A,
F [auth B],
G [auth D],
H [auth C]		IPR035761Ryanodine receptor, SPRY domain 1Domain
A,
F [auth B],
G [auth D],
H [auth C]		IPR014821Inositol 1,4,5-trisphosphate/ryanodine receptorDomain
A,
F [auth B],
G [auth D],
H [auth C]		IPR035764Ryanodine receptor, SPRY domain 2Domain
A,
F [auth B],
G [auth D],
H [auth C]		IPR013333Ryanodine receptorFamily
A,
F [auth B],
G [auth D],
H [auth C]		IPR043136B30.2/SPRY domain superfamilyHomologous Superfamily
A,
F [auth B],
G [auth D],
H [auth C]		IPR011992EF-hand domain pairHomologous Superfamily
A,
F [auth B],
G [auth D],
H [auth C]		IPR005821Ion transport domainDomain
A,
F [auth B],
G [auth D],
H [auth C]		IPR035762Ryanodine receptor, SPRY domain 3Domain
B [auth E],
C [auth H],
D [auth G],
E [auth F]		IPR046357Peptidyl-prolyl cis-trans isomerase domain superfamilyHomologous Superfamily
B [auth E],
C [auth H],
D [auth G],
E [auth F]		IPR050689FKBP-type Peptidyl-prolyl cis-trans IsomeraseFamily
B [auth E],
C [auth H],
D [auth G],
E [auth F]		IPR001179FKBP-type peptidyl-prolyl cis-trans isomerase domainDomain