Annotations: 8ZM3

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B [auth C]	PF09481	CRISPR-associated protein Cse1 (CRISPR_cse1) (CRISPR_Cse1)	CRISPR-associated protein Cse1 (CRISPR_cse1)	-	Family
C [auth E]	PF09485	CRISPR-associated protein Cse2 (CRISPR_cse2) (CRISPR_Cse2)	CRISPR-associated protein Cse2 (CRISPR_cse2)	-	Family
D [auth F], E [auth H], F [auth I], G [auth J], H [auth K], D [auth F], E [auth H], F [auth I], G [auth J], H [auth K], I [auth G]	PF09344	CT1975-like protein (Cas_CT1975)	CT1975-like protein	-	Family
J [auth B]	PF01844	HNH endonuclease (HNH)	HNH endonuclease	-	Family
J [auth B]	PF09704	CRISPR-associated protein (Cas_Cas5) (Cas_Cas5d)	CRISPR-associated protein (Cas_Cas5)	-	Family
K [auth D]	PF08798	CRISPR associated protein (CRISPR_assoc)	CRISPR associated protein	This domain forms an anti-parallel beta strand structure with flanking alpha helical regions.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	RNA (61-MER)	-	-	-
B [auth C]	CRISPR-associated protein Cse1 (CRISPR_cse1)	-	-	-
C [auth E]	CRISPR-associated protein Cse2 (CRISPR_cse2)	-	-	-
D [auth F], E [auth H], F [auth I], G [auth J], H [auth K], D [auth F], E [auth H], F [auth I], G [auth J], H [auth K], I [auth G]	CRISPR system Cascade subunit CasC	-	-	-
J [auth B]	CRISPR system Cascade subunit CasD	endonuclease activity nuclease activity hydrolase activity, acting on ester bonds hydrolase activity catalytic activity cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding RNA binding nucleic acid binding	biological process involved in interspecies interaction between organisms response to stimulus response to other organism defense response response to external stimulus response to biotic stimulus defense response to virus defense response to other organism response to stress response to external biotic stimulus response to virus maintenance of CRISPR repeat elements chromosome organization primary metabolic process biological process involved in interspecies interaction between organisms response to stimulus response to other organism defense response response to external stimulus response to biotic stimulus defense response to virus defense response to other organism response to stress response to external biotic stimulus response to virus maintenance of CRISPR repeat elements chromosome organization primary metabolic process DNA metabolic process maintenance of DNA repeat elements nucleic acid metabolic process cellular component organization nucleobase-containing compound metabolic process organelle organization cellular process metabolic process cellular component organization or biogenesis macromolecule metabolic process	-
K [auth D]	CRISPR-associated endoribonuclease Cse3	hydrolase activity catalytic activity	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B [auth C]	IPR013381	CRISPR-associated protein Cse1	Family
C [auth E]	IPR013382	CRISPR-associated protein Cse2	Family
C [auth E]	IPR038287	Cse2 superfamily	Homologous Superfamily
D [auth F], E [auth H], F [auth I], G [auth J], H [auth K], D [auth F], E [auth H], F [auth I], G [auth J], H [auth K], I [auth G]	IPR010148	CRISPR-associated protein, CT1975	Family
J [auth B]	IPR010147	CRISPR-associated protein, CasD	Family
J [auth B]	IPR021124	CRISPR-associated protein, Cas5	Family
J [auth B]	IPR003615	HNH nuclease	Domain
J [auth B]	IPR002711	HNH endonuclease	Domain
J [auth B]	IPR013422	CRISPR-associated protein Cas5, N-terminal	Domain
K [auth D]	IPR010179	CRISPR-associated protein Cse3	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.