Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ESCOP2B SuperfamilyDHS-like NAD/FAD-binding domain 8063732 3001728 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyDHS-like NAD/FAD-binding domain 8063732 3001728 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyDHS-like NAD/FAD-binding domain 8063732 3001728 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyDHS-like NAD/FAD-binding domain 8063732 3001728 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyDHS-like NAD/FAD-binding domain 8063732 3001728 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyDHS-like NAD/FAD-binding domain 8063732 3001728 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ESIR2_1ste6xv6E1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: DHS-like NAD/FAD-binding domainF: SIR2_1stECOD (1.6)
EKOG1905e6xv6E2 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: KOG1905ECOD (1.6)
ASIR2_1ste6xv6A1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: DHS-like NAD/FAD-binding domainF: SIR2_1stECOD (1.6)
AKOG1905e6xv6A2 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: KOG1905ECOD (1.6)
BSIR2_1ste6xv6B1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: DHS-like NAD/FAD-binding domainF: SIR2_1stECOD (1.6)
BKOG1905e6xv6B2 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: KOG1905ECOD (1.6)
CSIR2_1ste6xv6C1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: DHS-like NAD/FAD-binding domainF: SIR2_1stECOD (1.6)
CKOG1905e6xv6C2 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: KOG1905ECOD (1.6)
DSIR2_1ste6xv6D2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: DHS-like NAD/FAD-binding domainF: SIR2_1stECOD (1.6)
DKOG1905e6xv6D1 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: KOG1905ECOD (1.6)
FSIR2_1ste6xv6F1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: DHS-like NAD/FAD-binding domainF: SIR2_1stECOD (1.6)
FKOG1905e6xv6F2 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: KOG1905ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF02146Sir2 family (SIR2)Sir2 family- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
NAD-dependent protein deacetylase sirtuin-6

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR003000Sirtuin familyFamily
A, B, C, D, E
IPR029035DHS-like NAD/FAD-binding domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR026590Sirtuin family, catalytic core domainDomain
A, B, C, D, E
IPR050134NAD-dependent sirtuin protein deacylasesFamily

Pharos: Disease Associations Pharos Homepage Annotation