Annotations: 6MJ4


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
A [auth C]SCOP2B SuperfamilyImmunoglobulin (Ig) domain-like 8059663 3000071 SCOP2B (2022-06-29)
B [auth D]SCOP2B SuperfamilyImmunoglobulin (Ig) domain-like 8054445 3000071 SCOP2B (2022-06-29)
C [auth A]SCOP2B SuperfamilyImmunoglobulin (Ig) domain-like 8054657 3000071 SCOP2B (2022-06-29)
C [auth A]SCOP2B SuperfamilyMHC antigen-recognition domain 8037146 3000521 SCOP2B (2022-06-29)
D [auth B]SCOP2B SuperfamilyImmunoglobulin (Ig) domain-like 8054571 3000071 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth C]DUF1968e6mj4C2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF1968ECOD (1.6)
A [auth C]V-set_4e6mj4C1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_4ECOD (1.6)
B [auth D]C1-sete6mj4D2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-setECOD (1.6)
B [auth D]V-set_3e6mj4D1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)
C [auth A]C1-set_2e6mj4A1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
C [auth A]MHC_Ie6mj4A2 A: a+b two layersX: MHC antigen-recognition domain (From Topology)H: MHC antigen-recognition domain (From Topology)T: MHC antigen-recognition domainF: MHC_IECOD (1.6)
D [auth B]C1-set_2e6mj4B1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth C]PF07686Immunoglobulin V-set domain (V-set)Immunoglobulin V-set domainThis domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.Domain
A [auth C]PF09291Domain of unknown function (DUF1968) (DUF1968)Domain of unknown function (DUF1968)Members of this family are found in mammalian T-cell antigen receptor, and adopt an immunoglobulin-like beta-sandwich fold, with seven strands in two beta-sheets in a Greek-key topology. Their exact function has not, as yet, been determined.Domain
B [auth D]PF07686Immunoglobulin V-set domain (V-set)Immunoglobulin V-set domainThis domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.Domain
B [auth D]PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain
C [auth A]PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain
D [auth B]PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth C]T cell receptor alpha variable 11,T cell receptor alpha variable 11,T cell receptor alpha joining 18,Human nkt tcr alpha chain, chimeric protein- - -
B [auth D]Beta-chain,T cell receptor chain,T cell receptor beta constant 2, CHIMERIC PROTEIN-
C [auth A]Antigen-presenting glycoprotein CD1d1
D [auth B]Beta-2-microglobulin

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A [auth C]IPR051896T cell receptor alpha variable regionFamily
A [auth C]IPR013783Immunoglobulin-like foldHomologous Superfamily
A [auth C]IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
A [auth C]IPR013106Immunoglobulin V-set domainDomain
A [auth C]IPR007110Immunoglobulin-like domainDomain
A [auth C]IPR052051T cell receptor complex componentFamily
A [auth C]IPR013783Immunoglobulin-like foldHomologous Superfamily
A [auth C]IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
A [auth C]IPR013106Immunoglobulin V-set domainDomain
A [auth C]IPR003599Immunoglobulin domain subtypeDomain
A [auth C]IPR007110Immunoglobulin-like domainDomain
A [auth C]IPR015370T-cell receptor alpha chain, constant domainDomain
B [auth D]IPR003597Immunoglobulin C1-setDomain
B [auth D]IPR013783Immunoglobulin-like foldHomologous Superfamily
B [auth D]IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
B [auth D]IPR013106Immunoglobulin V-set domainDomain
B [auth D]IPR003599Immunoglobulin domain subtypeDomain
B [auth D]IPR007110Immunoglobulin-like domainDomain
B [auth D]IPR050413T cell receptor beta variableFamily
B [auth D]IPR013783Immunoglobulin-like foldHomologous Superfamily
B [auth D]IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
B [auth D]IPR013106Immunoglobulin V-set domainDomain
B [auth D]IPR003599Immunoglobulin domain subtypeDomain
B [auth D]IPR007110Immunoglobulin-like domainDomain
B [auth D]IPR050413T cell receptor beta variableFamily
B [auth D]IPR003597Immunoglobulin C1-setDomain
B [auth D]IPR013783Immunoglobulin-like foldHomologous Superfamily
B [auth D]IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
B [auth D]IPR007110Immunoglobulin-like domainDomain
B [auth D]IPR050380Immune Recognition and Response ModulatorsFamily
C [auth A]IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
C [auth A]IPR050208Antigen-presenting and immune regulatory MHC class I-relatedFamily
C [auth A]IPR003597Immunoglobulin C1-setDomain
C [auth A]IPR011161MHC class I-like antigen recognition-likeDomain
C [auth A]IPR011162MHC classes I/II-like antigen recognition proteinHomologous Superfamily
C [auth A]IPR037055MHC class I-like antigen recognition-like superfamilyHomologous Superfamily
C [auth A]IPR013783Immunoglobulin-like foldHomologous Superfamily
C [auth A]IPR007110Immunoglobulin-like domainDomain
D [auth B]IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
D [auth B]IPR050160Major Histocompatibility Complex/ImmunoglobulinFamily
D [auth B]IPR003597Immunoglobulin C1-setDomain
D [auth B]IPR015707Beta-2-MicroglobulinFamily
D [auth B]IPR003006Immunoglobulin/major histocompatibility complex, conserved siteConserved Site
D [auth B]IPR013783Immunoglobulin-like foldHomologous Superfamily
D [auth B]IPR007110Immunoglobulin-like domainDomain

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
B [auth D]PharosA0A5B9