6CWD | pdb_00006cwd

Hepatitis B core-antigen in complex with scFv e13

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B [auth D]	SCOP2B Superfamily	Hepatitis B viral capsid (hbcag)	8086395	3000581	SCOP2B (2022-06-29)
D [auth H]	SCOP2B Superfamily	Hepatitis B viral capsid (hbcag)	8086395	3000581	SCOP2B (2022-06-29)
F [auth C]	SCOP2B Superfamily	Hepatitis B viral capsid (hbcag)	8086395	3000581	SCOP2B (2022-06-29)
H [auth F]	SCOP2B Superfamily	Hepatitis B viral capsid (hbcag)	8086395	3000581	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth B]	V-set_8	e6cwdB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set_8	ECOD (1.6)
A [auth B]	V-set	e6cwdB2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set	ECOD (1.6)
C [auth G]	V-set_8	e6cwdG2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set_8	ECOD (1.6)
C [auth G]	V-set	e6cwdG1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set	ECOD (1.6)
E [auth A]	V-set_8	e6cwdA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set_8	ECOD (1.6)
E [auth A]	V-set	e6cwdA2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set	ECOD (1.6)
G [auth E]	V-set_8	e6cwdE2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set_8	ECOD (1.6)
G [auth E]	V-set	e6cwdE1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set	ECOD (1.6)
B [auth D]	Hepatitis_core	e6cwdD1	A: alpha arrays	X: Hepatitis B viral capsid (hbcag) (From Topology)	H: Hepatitis B viral capsid (hbcag) (From Topology)	T: Hepatitis B viral capsid (hbcag)	F: Hepatitis_core	ECOD (1.6)
D [auth H]	Hepatitis_core	e6cwdH1	A: alpha arrays	X: Hepatitis B viral capsid (hbcag) (From Topology)	H: Hepatitis B viral capsid (hbcag) (From Topology)	T: Hepatitis B viral capsid (hbcag)	F: Hepatitis_core	ECOD (1.6)
F [auth C]	Hepatitis_core	e6cwdC1	A: alpha arrays	X: Hepatitis B viral capsid (hbcag) (From Topology)	H: Hepatitis B viral capsid (hbcag) (From Topology)	T: Hepatitis B viral capsid (hbcag)	F: Hepatitis_core	ECOD (1.6)
H [auth F]	Hepatitis_core	e6cwdF1	A: alpha arrays	X: Hepatitis B viral capsid (hbcag) (From Topology)	H: Hepatitis B viral capsid (hbcag) (From Topology)	T: Hepatitis B viral capsid (hbcag)	F: Hepatitis_core	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B [auth D]	1.10.4090.10	Mainly Alpha	Orthogonal Bundle	Hepatitis B viral capsid (hbcag) fold	Viral capsid, core domain supefamily, Hepatitis B virus	CATH (4.3.0)
D [auth H]	1.10.4090.10	Mainly Alpha	Orthogonal Bundle	Hepatitis B viral capsid (hbcag) fold	Viral capsid, core domain supefamily, Hepatitis B virus	CATH (4.3.0)
F [auth C]	1.10.4090.10	Mainly Alpha	Orthogonal Bundle	Hepatitis B viral capsid (hbcag) fold	Viral capsid, core domain supefamily, Hepatitis B virus	CATH (4.3.0)
H [auth F]	1.10.4090.10	Mainly Alpha	Orthogonal Bundle	Hepatitis B viral capsid (hbcag) fold	Viral capsid, core domain supefamily, Hepatitis B virus	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth B], C [auth G], E [auth A], G [auth E]	Single chain variable fragment (scFv) e13	-	-	-
B [auth D], D [auth H], F [auth C], H [auth F]	Capsid protein	DNA binding binding nucleic acid binding structural molecule activity RNA binding identical protein binding protein binding	biological process involved in interspecies interaction between organisms microtubule-dependent intracellular transport of viral material microtubule-dependent intracellular transport of viral material towards nucleus intracellular transport of virus viral process viral life cycle transport of virus transport of viral material towards nucleus biological process involved in symbiotic interaction viral penetration into host nucleus symbiont entry into host cell symbiont entry into host biological process involved in interaction with host	host cellular component cellular anatomical structure host cell viral capsid icosahedral viral capsid T=4 icosahedral viral capsid virion component host intracellular part host cell cytoplasm host cell part host intracellular region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B [auth D], D [auth H], F [auth C], H [auth F]	IPR036459	Viral capsid core domain supefamily, Hepatitis B virus	Homologous Superfamily
B [auth D], D [auth H], F [auth C], H [auth F]	IPR002006	Hepatitis core antigen	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.