Human DNA polymerase eta R61A-DNA ternary complex: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion
External Resource: Annotation
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
A | SCOP2B Superfamily | Ta1206-like | 8101835 | 3001431 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Nucleotide cyclase/DNA polymerase palm domain-like | 8101834 | 3001272 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Nucleotide cyclase/DNA polymerase palm domain-like | 8101834 | 3001272 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Lesion bypass DNA polymerase (Y-family), little finger domain | 8101833 | 3000579 | SCOP2B (2022-06-29) |
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
A | KOG2095_1st | e5kfsA1 | A: alpha arrays | X: HhH/H2TH | H: SAM/DNA-glycosylase | T: SAM domain-like | F: KOG2095_1st | ECOD (1.6) |
A | IMS_C | e5kfsA4 | A: a+b two layers | X: Reverse ferredoxin | H: Lesion bypass DNA polymerase (Y-family), little finger domain (From Topology) | T: Lesion bypass DNA polymerase (Y-family), little finger domain | F: IMS_C | ECOD (1.6) |
A | IMS | e5kfsA3 | A: a+b two layers | X: Alpha-beta plaits | H: Adenylyl and guanylyl cyclase catalytic domain-like | T: Adenylyl and guanylyl cyclase catalytic domain-like | F: IMS | ECOD (1.6) |
A | IMS_1 | e5kfsA2 | A: a+b three layers | X: Hypothetical protein Ta1206-like (From Topology) | H: Hypothetical protein Ta1206-like (From Topology) | T: Hypothetical protein Ta1206-like | F: IMS_1 | ECOD (1.6) |
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
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| DNA polymerase eta | | | |
B [auth T] | DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3') | - | - | - |
C [auth P] | DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3') | - | - | - |
Chains | Drug Target   | Associated Disease |
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| Pharos:  Q9Y253 | |