Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad4q33a_ Alpha and beta proteins (a/b) TIM beta/alpha-barrel Inosine monophosphate dehydrogenase (IMPDH) automated matches automated matches (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], SCOPe (2.08)
Cd4q33c_ Alpha and beta proteins (a/b) TIM beta/alpha-barrel Inosine monophosphate dehydrogenase (IMPDH) automated matches automated matches (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], SCOPe (2.08)
Dd4q33d_ Alpha and beta proteins (a/b) TIM beta/alpha-barrel Inosine monophosphate dehydrogenase (IMPDH) automated matches automated matches (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], SCOPe (2.08)
Fd4q33f_ Alpha and beta proteins (a/b) TIM beta/alpha-barrel Inosine monophosphate dehydrogenase (IMPDH) automated matches automated matches (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], SCOPe (2.08)
Gd4q33g_ Alpha and beta proteins (a/b) TIM beta/alpha-barrel Inosine monophosphate dehydrogenase (IMPDH) automated matches automated matches (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], SCOPe (2.08)
Hd4q33h_ Alpha and beta proteins (a/b) TIM beta/alpha-barrel Inosine monophosphate dehydrogenase (IMPDH) automated matches automated matches (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], SCOPe (2.08)
Bd4q33b_ Alpha and beta proteins (a/b) TIM beta/alpha-barrel Inosine monophosphate dehydrogenase (IMPDH) automated matches automated matches (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], SCOPe (2.08)
Ed4q33e_ Alpha and beta proteins (a/b) TIM beta/alpha-barrel Inosine monophosphate dehydrogenase (IMPDH) automated matches automated matches (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], (Clostridium perfringens ATCC 13124 ) [TaxId: 195103 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AIMPDH_1ste4q33A1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: IMPDH_1stECOD (1.6)
CIMPDH_1ste4q33C1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: IMPDH_1stECOD (1.6)
DIMPDH_1ste4q33D1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: IMPDH_1stECOD (1.6)
FIMPDH_1ste4q33F1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: IMPDH_1stECOD (1.6)
GIMPDH_1ste4q33G1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: IMPDH_1stECOD (1.6)
HIMPDH_1ste4q33H1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: IMPDH_1stECOD (1.6)
BIMPDH_1ste4q33B1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: IMPDH_1stECOD (1.6)
EIMPDH_1ste4q33E1 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: IMPDH_1stECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.20.20.70 Alpha Beta Alpha-Beta Barrel TIM Barrel Aldolase class ICATH (4.3.0)
C3.20.20.70 Alpha Beta Alpha-Beta Barrel TIM Barrel Aldolase class ICATH (4.3.0)
D3.20.20.70 Alpha Beta Alpha-Beta Barrel TIM Barrel Aldolase class ICATH (4.3.0)
F3.20.20.70 Alpha Beta Alpha-Beta Barrel TIM Barrel Aldolase class ICATH (4.3.0)
G3.20.20.70 Alpha Beta Alpha-Beta Barrel TIM Barrel Aldolase class ICATH (4.3.0)
H3.20.20.70 Alpha Beta Alpha-Beta Barrel TIM Barrel Aldolase class ICATH (4.3.0)
B3.20.20.70 Alpha Beta Alpha-Beta Barrel TIM Barrel Aldolase class ICATH (4.3.0)
E3.20.20.70 Alpha Beta Alpha-Beta Barrel TIM Barrel Aldolase class ICATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF00478IMP dehydrogenase / GMP reductase domain (IMPDH)IMP dehydrogenase / GMP reductase domainThis family is involved in biosynthesis of guanosine nucleotide. Members of this family contain a TIM barrel structure. In the inosine monophosphate dehydrogenases 2 CBS domains Pfam:PF00571 are inserted in the TIM barrel [2]. This family is a membe ...This family is involved in biosynthesis of guanosine nucleotide. Members of this family contain a TIM barrel structure. In the inosine monophosphate dehydrogenases 2 CBS domains Pfam:PF00571 are inserted in the TIM barrel [2]. This family is a member of the common phosphate binding site TIM barrel family.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
Inosine-5'-monophosphate dehydrogenase -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR046342CBS domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR000644CBS domainDomain
A, B, C, D, E
IPR001093IMP dehydrogenase/GMP reductaseDomain
A, B, C, D, E
IPR013785Aldolase-type TIM barrelHomologous Superfamily
A, B, C, D, E
IPR005990Inosine-5'-monophosphate dehydrogenaseFamily
A, B, C, D, E
IPR015875IMP dehydrogenase / GMP reductase, conserved siteConserved Site