4JA4 | pdb_00004ja4

Inward open conformation of the xylose transporter XylE from E. coli

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	MFS_1	e4ja4A1	A: alpha complex topology	X: Major facilitator superfamily (MFS) general substrate transporter (From Topology)	H: Major facilitator superfamily (MFS) general substrate transporter (From Topology)	T: Major facilitator superfamily (MFS) general substrate transporter	F: MFS_1	ECOD (1.6)
B	MFS_1	e4ja4B1	A: alpha complex topology	X: Major facilitator superfamily (MFS) general substrate transporter (From Topology)	H: Major facilitator superfamily (MFS) general substrate transporter (From Topology)	T: Major facilitator superfamily (MFS) general substrate transporter	F: MFS_1	ECOD (1.6)
C	MFS_1	e4ja4C1	A: alpha complex topology	X: Major facilitator superfamily (MFS) general substrate transporter (From Topology)	H: Major facilitator superfamily (MFS) general substrate transporter (From Topology)	T: Major facilitator superfamily (MFS) general substrate transporter	F: MFS_1	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF00083	Sugar (and other) transporter (Sugar_tr)	Sugar (and other) transporter	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C	D-xylose-proton symporter	monoatomic cation transmembrane transporter activity D-xylose transmembrane transporter activity monosaccharide transmembrane transporter activity sugar transmembrane transporter activity proton transmembrane transporter activity solute:monoatomic cation symporter activity pentose transmembrane transporter activity secondary active transmembrane transporter activity carbohydrate:monoatomic cation symporter activity D-xylose:proton symporter activity carbohydrate:proton symporter activity active transmembrane transporter activity inorganic molecular entity transmembrane transporter activity solute:proton symporter activity inorganic cation transmembrane transporter activity monoatomic cation transmembrane transporter activity D-xylose transmembrane transporter activity monosaccharide transmembrane transporter activity sugar transmembrane transporter activity proton transmembrane transporter activity solute:monoatomic cation symporter activity pentose transmembrane transporter activity secondary active transmembrane transporter activity carbohydrate:monoatomic cation symporter activity D-xylose:proton symporter activity carbohydrate:proton symporter activity active transmembrane transporter activity inorganic molecular entity transmembrane transporter activity solute:proton symporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity carbohydrate transmembrane transporter activity transmembrane transporter activity symporter activity	transmembrane transport localization D-xylose transmembrane transport pentose transmembrane transport transport carbohydrate transport cellular process monosaccharide transmembrane transport carbohydrate transmembrane transport establishment of localization	cellular anatomical structure membrane cell periphery plasma membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C	IPR003663	Sugar/inositol transporter	Family
A, B, C	IPR005828	Major facilitator, sugar transporter-like	Family
A, B, C	IPR005829	Sugar transporter, conserved site	Conserved Site
A, B, C	IPR050814	Myo-inositol Transporter	Family
A, B, C	IPR036259	MFS transporter superfamily	Homologous Superfamily
A, B, C	IPR047984	D-xylose-proton symporter-like	Family
A, B, C	IPR020846	Major facilitator superfamily domain	Domain

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A, B, C	OPM	Transmembrane	Alpha-helical polytopic	Major Facilitator Superfamily (MFS)	Sugar porter family

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B, C	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A, B, C	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B, C	mpstruc	TRANSMEMBRANE PROTEINS: ALPHA-HELICAL	Major Facilitator Superfamily (MFS) Transporters	XylE proton:xylose symporter in partially occluded inward-open state

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.