4HEP
Complex of lactococcal phage TP901-1 with a llama vHH (vHH17) binder (nanobody)
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d4hepa2 | All beta proteins | Virus attachment protein globular domain | Virus attachment protein globular domain | Lactophage receptor-binding protein head domain | automated matches | (Lactococcus phage TP901-1 ) [TaxId: 35345 ], | SCOPe (2.08) |
A | d4hepa1 | All beta proteins | Triple-stranded beta-helix | Phage fibre proteins | automated matches | automated matches | (Lactococcus phage TP901-1 ) [TaxId: 35345 ], | SCOPe (2.08) |
B [auth G] | d4hepg_ | All beta proteins | Immunoglobulin-like beta-sandwich | Immunoglobulin | V set domains (antibody variable domain-like) | automated matches | Llama (Lama glama ) [TaxId: 9844 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Caudo_bapla_RBP_3rd | e4hepA1 | A: beta sandwiches | X: Domain in virus attachment proteins (From Topology) | H: Domain in virus attachment proteins (From Topology) | T: Domain in virus attachment proteins | F: Caudo_bapla_RBP_3rd | ECOD (1.6) |
A | EUF07875 | e4hepA2 | A: beta duplicates or obligate multimers | X: Phage tail fiber protein trimerization domain (From Topology) | H: Phage tail fiber protein trimerization domain (From Topology) | T: Phage tail fiber protein trimerization domain | F: EUF07875 | ECOD (1.6) |
B [auth G] | V-set_10 | e4hepG1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_10 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 6.10.140.2190 | Special | Helix non-globular | Helix Hairpins | CATH (4.3.0) | |
A | 2.60.40.1830 | Mainly Beta | Sandwich | Immunoglobulin-like | Phage tail base-plate Siphoviridae RBP, head domain | CATH (4.3.0) |
B [auth G] | 2.60.40.10 | Mainly Beta | Sandwich | Immunoglobulin-like | Immunoglobulins | CATH (4.3.0) |
IMGT Antibody Annotation IMGT Database Homepage
Chain | Protein Name | Description | Organism Name | Gene Allele Name(s) | Domain Name(s) | Receptor Type | Receptor Description | Provenance Source |
---|---|---|---|---|---|---|---|---|
B [auth G] | vHH17 domain | VH | Lama glama (llama) | IGHV3S1*01, IGHV3S2*01, IGHJ4*01 | V-DOMAIN VH | IG | (VH) | IMGT (202500-0) |
SAbDab Antibody Annotation SAbDab Database Homepage
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|---|---|---|---|---|
B [auth G] | Heavy Chain | IGHV1 | - | bpp | SAbDab (2025-01-10) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF18338 | Lower baseplate protein N-terminal domain (BppL_N) | Lower baseplate protein N-terminal domain | - | Repeat | |
PF08931 | Lactophage receptor-binding protein C-terminal head domain (Caudo_bapla_RBP) | Lactophage receptor-binding protein C-terminal head domain | Caudo_bapla_RBP is a family of proteins expressed from ORF18 of the Lactococcus P2-like phage. This is one of three protein domains, shoulders, neck, and head, that form the phage tail base-plate. In the overall structure this head domain exists as s ... | Domain | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
---|---|---|---|---|
BPP | - |
| ||
B [auth G] | vHH17 domain | - | - | - |
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR008982 | Adenovirus pIV-like, attachment domain | Homologous Superfamily | |
IPR015027 | Receptor-binding protein of phage tail base-plate Siphoviridae, head | Domain | |
IPR040956 | Lower baseplate protein, N-terminal | Domain |