4FK2
RB69 DNA polymerase ternary complex with dTTP/dG
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d4fk2a1 | Alpha and beta proteins (a/b) | Ribonuclease H-like motif | Ribonuclease H-like | DnaQ-like 3'-5' exonuclease | Exonuclease domain of family B DNA polymerases | (Escherichia phage RB69 ) [TaxId: 12353 ], | SCOPe (2.08) |
A | d4fk2a2 | Multi-domain proteins (alpha and beta) | DNA/RNA polymerases | DNA/RNA polymerases | DNA polymerase I | Family B DNA polymerase | (Escherichia phage RB69 ) [TaxId: 12353 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | Ribonuclease H-like | 8033947 | 3000143 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Nucleotide cyclase/DNA polymerase palm domain-like | 8033949 | 3001272 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Nucleotide cyclase/DNA polymerase palm domain-like | 8033949 | 3001272 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | 43_2nd | e4fk2A5 | A: alpha bundles | X: thumb domain in bacteriophage RB69-like DNA polymerase I (From Topology) | H: thumb domain in bacteriophage RB69-like DNA polymerase I (From Topology) | T: thumb domain in bacteriophage RB69-like DNA polymerase I | F: 43_2nd | ECOD (1.6) |
A | 43_1st | e4fk2A6 | A: alpha bundles | X: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology) | H: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology) | T: fingers domain in bacteriophage RB69-like DNA polymerase I | F: 43_1st | ECOD (1.6) |
A | DNA_pol_B_1st | e4fk2A7 | A: a+b two layers | X: Alpha-beta plaits | H: Adenylyl and guanylyl cyclase catalytic domain-like | T: Adenylyl and guanylyl cyclase catalytic domain-like | F: DNA_pol_B_1st | ECOD (1.6) |
A | DNA_pol_B_exo1_3rd | e4fk2A4 | A: mixed a+b and a/b | X: Ribonuclease H-like | H: Ribonuclease H-like (From Topology) | T: Ribonuclease H-like | F: DNA_pol_B_exo1_3rd | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.30.342.10 | Alpha Beta | 2-Layer Sandwich | DNA Polymerase | Chain A, domain 1 | CATH (4.3.0) |
A | 3.30.420.10 | Alpha Beta | 2-Layer Sandwich | Nucleotidyltransferase | domain 5 | CATH (4.3.0) |
A | 3.90.1600.10 | Alpha Beta | Alpha-Beta Complex | Palm domain of DNA polymerase | B family DNA polymerase, palm domain | CATH (4.3.0) |
A | 1.10.287.690 | Mainly Alpha | Orthogonal Bundle | Helix Hairpins | B family DNA polymerase, finger domain | CATH (4.3.0) |
A | 1.20.1280.300 | Mainly Alpha | Up-down Bundle | Monooxygenase | CATH (4.3.0) | |
A | 3.40.1820.10 | Alpha Beta | 3-Layer(aba) Sandwich | Ribonuclease H-like motif | DnaQ-like 3'-5' exonuclease | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF03104 | DNA polymerase family B, exonuclease domain (DNA_pol_B_exo1) | DNA polymerase family B, exonuclease domain | - | Family | |
PF00136 | DNA polymerase family B (DNA_pol_B) | DNA polymerase family B | - | Family | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR036397 | Ribonuclease H superfamily | Homologous Superfamily | |
IPR006134 | DNA-directed DNA polymerase, family B, multifunctional domain | Domain | |
IPR034749 | DNA-directed DNA polymerase T4 type | Family | |
IPR006172 | DNA-directed DNA polymerase, family B | Family | |
IPR043502 | DNA/RNA polymerase superfamily | Homologous Superfamily | |
IPR006133 | DNA-directed DNA polymerase, family B, exonuclease domain | Domain | |
IPR050240 | DNA polymerase type-B | Family | |
IPR017964 | DNA-directed DNA polymerase, family B, conserved site | Conserved Site | |
IPR012337 | Ribonuclease H-like superfamily | Homologous Superfamily | |
IPR023211 | DNA polymerase, palm domain superfamily | Homologous Superfamily |