3TCG | pdb_00003tcg

Crystal structure of E. coli OppA complexed with the tripeptide KGE

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d3tcgb_	Alpha and beta proteins (a/b)	Periplasmic binding protein-like II	Periplasmic binding protein-like II	Phosphate binding protein-like	automated matches	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
C	d3tcgc_	Alpha and beta proteins (a/b)	Periplasmic binding protein-like II	Periplasmic binding protein-like II	Phosphate binding protein-like	automated matches	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
D	d3tcgd_	Alpha and beta proteins (a/b)	Periplasmic binding protein-like II	Periplasmic binding protein-like II	Phosphate binding protein-like	automated matches	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
E	d3tcge_	Alpha and beta proteins (a/b)	Periplasmic binding protein-like II	Periplasmic binding protein-like II	Phosphate binding protein-like	automated matches	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
F	d3tcgf_	Alpha and beta proteins (a/b)	Periplasmic binding protein-like II	Periplasmic binding protein-like II	Phosphate binding protein-like	automated matches	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
G	d3tcgg_	Alpha and beta proteins (a/b)	Periplasmic binding protein-like II	Periplasmic binding protein-like II	Phosphate binding protein-like	automated matches	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
H	d3tcgh_	Alpha and beta proteins (a/b)	Periplasmic binding protein-like II	Periplasmic binding protein-like II	Phosphate binding protein-like	automated matches	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)
A	d3tcga_	Alpha and beta proteins (a/b)	Periplasmic binding protein-like II	Periplasmic binding protein-like II	Phosphate binding protein-like	automated matches	(Escherichia coli K-12 ) [TaxId: 83333 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Type 2 solute binding protein-like	8072677	3000083	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Type 2 solute binding protein-like	8072677	3000083	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Type 2 solute binding protein-like	8072677	3000083	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Type 2 solute binding protein-like	8072677	3000083	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Type 2 solute binding protein-like	8072677	3000083	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Type 2 solute binding protein-like	8072677	3000083	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Type 2 solute binding protein-like	8072677	3000083	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Type 2 solute binding protein-like	8072677	3000083	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	SBP_bac_5_1st	e3tcgB3	A: a+b two layers	X: Alpha-beta plaits	H: Oligo-peptide binding protein (OPPA) insertion domain (From Topology)	T: Oligo-peptide binding protein (OPPA) insertion domain	F: SBP_bac_5_1st	ECOD (1.6)
B	SBP_bac_5_3rd	e3tcgB4	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_3rd	ECOD (1.6)
B	SBP_bac_5_2nd	e3tcgB1	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_2nd	ECOD (1.6)
C	SBP_bac_5_1st	e3tcgC3	A: a+b two layers	X: Alpha-beta plaits	H: Oligo-peptide binding protein (OPPA) insertion domain (From Topology)	T: Oligo-peptide binding protein (OPPA) insertion domain	F: SBP_bac_5_1st	ECOD (1.6)
C	SBP_bac_5_3rd	e3tcgC1	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_3rd	ECOD (1.6)
C	SBP_bac_5_2nd	e3tcgC4	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_2nd	ECOD (1.6)
D	SBP_bac_5_1st	e3tcgD3	A: a+b two layers	X: Alpha-beta plaits	H: Oligo-peptide binding protein (OPPA) insertion domain (From Topology)	T: Oligo-peptide binding protein (OPPA) insertion domain	F: SBP_bac_5_1st	ECOD (1.6)
D	SBP_bac_5_3rd	e3tcgD1	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_3rd	ECOD (1.6)
D	SBP_bac_5_2nd	e3tcgD4	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_2nd	ECOD (1.6)
E	SBP_bac_5_1st	e3tcgE3	A: a+b two layers	X: Alpha-beta plaits	H: Oligo-peptide binding protein (OPPA) insertion domain (From Topology)	T: Oligo-peptide binding protein (OPPA) insertion domain	F: SBP_bac_5_1st	ECOD (1.6)
E	SBP_bac_5_3rd	e3tcgE4	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_3rd	ECOD (1.6)
E	SBP_bac_5_2nd	e3tcgE1	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_2nd	ECOD (1.6)
F	SBP_bac_5_1st	e3tcgF3	A: a+b two layers	X: Alpha-beta plaits	H: Oligo-peptide binding protein (OPPA) insertion domain (From Topology)	T: Oligo-peptide binding protein (OPPA) insertion domain	F: SBP_bac_5_1st	ECOD (1.6)
F	SBP_bac_5_3rd	e3tcgF4	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_3rd	ECOD (1.6)
F	SBP_bac_5_2nd	e3tcgF2	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_2nd	ECOD (1.6)
G	SBP_bac_5_1st	e3tcgG3	A: a+b two layers	X: Alpha-beta plaits	H: Oligo-peptide binding protein (OPPA) insertion domain (From Topology)	T: Oligo-peptide binding protein (OPPA) insertion domain	F: SBP_bac_5_1st	ECOD (1.6)
G	SBP_bac_5_3rd	e3tcgG4	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_3rd	ECOD (1.6)
G	SBP_bac_5_2nd	e3tcgG1	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_2nd	ECOD (1.6)
H	SBP_bac_5_1st	e3tcgH3	A: a+b two layers	X: Alpha-beta plaits	H: Oligo-peptide binding protein (OPPA) insertion domain (From Topology)	T: Oligo-peptide binding protein (OPPA) insertion domain	F: SBP_bac_5_1st	ECOD (1.6)
H	SBP_bac_5_3rd	e3tcgH1	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_3rd	ECOD (1.6)
H	SBP_bac_5_2nd	e3tcgH4	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_2nd	ECOD (1.6)
A	SBP_bac_5_1st	e3tcgA3	A: a+b two layers	X: Alpha-beta plaits	H: Oligo-peptide binding protein (OPPA) insertion domain (From Topology)	T: Oligo-peptide binding protein (OPPA) insertion domain	F: SBP_bac_5_1st	ECOD (1.6)
A	SBP_bac_5_3rd	e3tcgA2	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_3rd	ECOD (1.6)
A	SBP_bac_5_2nd	e3tcgA1	A: a/b three-layered sandwiches	X: Periplasmic binding protein-like II (From Topology)	H: Periplasmic binding protein-like II (From Topology)	T: Periplasmic binding protein-like II	F: SBP_bac_5_2nd	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.40.190.10	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein	domain 2	CATH (4.3.0)
B	3.90.76.10	Alpha Beta	Alpha-Beta Complex	Dipeptide-binding Protein	domain 1	CATH (4.3.0)
B	3.10.105.10	Alpha Beta	Roll	Dipeptide-binding Protein	domain 3	CATH (4.3.0)
C	3.40.190.10	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein	domain 2	CATH (4.3.0)
C	3.90.76.10	Alpha Beta	Alpha-Beta Complex	Dipeptide-binding Protein	domain 1	CATH (4.3.0)
C	3.10.105.10	Alpha Beta	Roll	Dipeptide-binding Protein	domain 3	CATH (4.3.0)
D	3.40.190.10	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein	domain 2	CATH (4.3.0)
D	3.90.76.10	Alpha Beta	Alpha-Beta Complex	Dipeptide-binding Protein	domain 1	CATH (4.3.0)
D	3.10.105.10	Alpha Beta	Roll	Dipeptide-binding Protein	domain 3	CATH (4.3.0)
E	3.40.190.10	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein	domain 2	CATH (4.3.0)
E	3.90.76.10	Alpha Beta	Alpha-Beta Complex	Dipeptide-binding Protein	domain 1	CATH (4.3.0)
E	3.10.105.10	Alpha Beta	Roll	Dipeptide-binding Protein	domain 3	CATH (4.3.0)
F	3.40.190.10	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein	domain 2	CATH (4.3.0)
F	3.90.76.10	Alpha Beta	Alpha-Beta Complex	Dipeptide-binding Protein	domain 1	CATH (4.3.0)
F	3.10.105.10	Alpha Beta	Roll	Dipeptide-binding Protein	domain 3	CATH (4.3.0)
G	3.40.190.10	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein	domain 2	CATH (4.3.0)
G	3.90.76.10	Alpha Beta	Alpha-Beta Complex	Dipeptide-binding Protein	domain 1	CATH (4.3.0)
G	3.10.105.10	Alpha Beta	Roll	Dipeptide-binding Protein	domain 3	CATH (4.3.0)
H	3.40.190.10	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein	domain 2	CATH (4.3.0)
H	3.90.76.10	Alpha Beta	Alpha-Beta Complex	Dipeptide-binding Protein	domain 1	CATH (4.3.0)
H	3.10.105.10	Alpha Beta	Roll	Dipeptide-binding Protein	domain 3	CATH (4.3.0)
A	3.40.190.10	Alpha Beta	3-Layer(aba) Sandwich	D-Maltodextrin-Binding Protein	domain 2	CATH (4.3.0)
A	3.90.76.10	Alpha Beta	Alpha-Beta Complex	Dipeptide-binding Protein	domain 1	CATH (4.3.0)
A	3.10.105.10	Alpha Beta	Roll	Dipeptide-binding Protein	domain 3	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF00496	Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)	Bacterial extracellular solute-binding proteins, family 5 Middle	The borders of this family are based on the PDBSum definitions of the domain edges for Swiss:P06202.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Periplasmic oligopeptide-binding protein	peptide transmembrane transporter activity transporter activity transmembrane transporter activity amide binding binding oligopeptide binding	peptide transport localization nitrogen compound transport amide transport transport establishment of localization primary metabolic process gene expression chaperone-mediated protein folding macromolecule biosynthetic process protein maturation protein folding biosynthetic process metabolic process peptide transport localization nitrogen compound transport amide transport transport establishment of localization primary metabolic process gene expression chaperone-mediated protein folding macromolecule biosynthetic process protein maturation protein folding biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process import into cell oligopeptide transport import across plasma membrane transmembrane transport oligopeptide transmembrane transport oligopeptide import across plasma membrane protein localization establishment of protein localization cellular localization protein transport cellular macromolecule localization macromolecule localization response to stimulus response to stress response to heat response to abiotic stimulus response to temperature stimulus	cellular anatomical structure membrane ATPase dependent transmembrane transport complex ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing protein-containing complex plasma membrane protein complex plasma membrane membrane protein complex transporter complex ATP-binding cassette (ABC) transporter complex cell periphery transmembrane transporter complex outer membrane-bounded periplasmic space cell envelope cellular anatomical structure membrane ATPase dependent transmembrane transport complex ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing protein-containing complex plasma membrane protein complex plasma membrane membrane protein complex transporter complex ATP-binding cassette (ABC) transporter complex cell periphery transmembrane transporter complex outer membrane-bounded periplasmic space cell envelope periplasmic space
I, J, K, L, M I, J, K, L, M, N, O, P	KGE Peptide	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR030678	Peptide/nickel binding protein, MppA-type	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR023765	Solute-binding protein family 5, conserved site	Conserved Site
A, B, C, D, E A, B, C, D, E, F, G, H	IPR000914	Solute-binding protein family 5 domain	Domain
A, B, C, D, E A, B, C, D, E, F, G, H	IPR039424	Solute-binding protein family 5	Family