Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AUDPG_MGDP_dhe2qg4A2 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: UDPG_MGDP_dhECOD (1.6)
ANAD_binding_2e2qg4A3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: NAD_binding_2ECOD (1.6)
AUDPG_MGDP_dh_Ce2qg4A1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: UDPG/MGDP dehydrogenase C-terminal domainF: UDPG_MGDP_dh_CECOD (1.6)
CUDPG_MGDP_dhe2qg4C3 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: UDPG_MGDP_dhECOD (1.6)
CNAD_binding_2e2qg4C1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: NAD_binding_2ECOD (1.6)
CUDPG_MGDP_dh_Ce2qg4C2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: UDPG/MGDP dehydrogenase C-terminal domainF: UDPG_MGDP_dh_CECOD (1.6)
BUDPG_MGDP_dhe2qg4B2 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: UDPG_MGDP_dhECOD (1.6)
BNAD_binding_2e2qg4B3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: NAD_binding_2ECOD (1.6)
BUDPG_MGDP_dh_Ce2qg4B1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: UDPG/MGDP dehydrogenase C-terminal domainF: UDPG_MGDP_dh_CECOD (1.6)
DUDPG_MGDP_dhe2qg4D2 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: UDPG_MGDP_dhECOD (1.6)
DNAD_binding_2e2qg4D3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: NAD_binding_2ECOD (1.6)
DUDPG_MGDP_dh_Ce2qg4D1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: UDPG/MGDP dehydrogenase C-terminal domainF: UDPG_MGDP_dh_CECOD (1.6)
EUDPG_MGDP_dhe2qg4E2 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: UDPG_MGDP_dhECOD (1.6)
ENAD_binding_2e2qg4E1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: NAD_binding_2ECOD (1.6)
EUDPG_MGDP_dh_Ce2qg4E3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: UDPG/MGDP dehydrogenase C-terminal domainF: UDPG_MGDP_dh_CECOD (1.6)
FUDPG_MGDP_dhe2qg4F1 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: UDPG_MGDP_dhECOD (1.6)
FNAD_binding_2e2qg4F3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: NAD_binding_2ECOD (1.6)
FUDPG_MGDP_dh_Ce2qg4F2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: UDPG/MGDP dehydrogenase C-terminal domainF: UDPG_MGDP_dh_CECOD (1.6)
GUDPG_MGDP_dhe2qg4G1 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: UDPG_MGDP_dhECOD (1.6)
GNAD_binding_2e2qg4G3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: NAD_binding_2ECOD (1.6)
GUDPG_MGDP_dh_Ce2qg4G2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: UDPG/MGDP dehydrogenase C-terminal domainF: UDPG_MGDP_dh_CECOD (1.6)
HUDPG_MGDP_dhe2qg4H1 A: alpha arraysX: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)H: 6-phosphogluconate dehydrogenase C-terminal domain-like (From Topology)T: 6-phosphogluconate dehydrogenase C-terminal domain-likeF: UDPG_MGDP_dhECOD (1.6)
HNAD_binding_2e2qg4H2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: NAD(P)-binding Rossmann-fold domainsF: NAD_binding_2ECOD (1.6)
HUDPG_MGDP_dh_Ce2qg4H3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: UDPG/MGDP dehydrogenase C-terminal domainF: UDPG_MGDP_dh_CECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
A1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)
C3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
C1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)
B3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
B1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)
D3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
D1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)
E3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
E1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)
F3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
F1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)
G3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
G1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)
H3.40.50.720 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold NAD(P)-binding Rossmann-like DomainCATH (4.3.0)
H1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF03720UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain (UDPG_MGDP_dh_C)UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domainThe UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate [2].Domain
A, B, C, D, E
PF03721UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain (UDPG_MGDP_dh_N)UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domainThe UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate [2].Domain
A, B, C, D, E
PF00984UDP-glucose/GDP-mannose dehydrogenase family, central domain (UDPG_MGDP_dh)UDP-glucose/GDP-mannose dehydrogenase family, central domainThe UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate [2].Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
UDP-glucose 6-dehydrogenase