2MRB | pdb_00002mrb

THREE-DIMENSIONAL STRUCTURE OF RABBIT LIVER CD-7 METALLOTHIONEIN-2A IN AQUEOUS SOLUTION DETERMINED BY NUCLEAR MAGNETIC RESONANCE

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2mrba_	Small proteins	Metallothionein	Metallothionein	Metallothionein	Metallothionein	rabbit (Oryctolagus cuniculus ) [TaxId: 9986 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Metallothionein	8026924	4003746	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Metallothionein	8039303	3001404	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Metallothio_8	e2mrbA1	A: few secondary structure elements	X: Metallothionein (From Topology)	H: Metallothionein (From Topology)	T: Metallothionein	F: Metallothio_8	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00131	Metallothionein (Metallothio)	Metallothionein		Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	CD7 METALLOTHIONEIN-2A	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding	cellular response to stimulus response to copper ion cellular response to metal ion cellular response to chemical stimulus response to stimulus response to metal ion response to chemical cellular process cellular response to copper ion detoxification of inorganic compound detoxification of copper ion detoxification stress response to copper ion response to toxic substance cellular response to stimulus response to copper ion cellular response to metal ion cellular response to chemical stimulus response to stimulus response to metal ion response to chemical cellular process cellular response to copper ion detoxification of inorganic compound detoxification of copper ion detoxification stress response to copper ion response to toxic substance response to stress stress response to metal ion response to zinc ion cellular response to zinc ion regulation of biological process regulation of growth negative regulation of growth negative regulation of biological process biological regulation growth cellular response to cadmium ion response to cadmium ion inorganic ion homeostasis cellular homeostasis chemical homeostasis homeostatic process intracellular monoatomic cation homeostasis intracellular zinc ion homeostasis monoatomic ion homeostasis intracellular chemical homeostasis monoatomic cation homeostasis intracellular monoatomic ion homeostasis	cellular anatomical structure intracellular anatomical structure cytoplasm membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR017854	Metallothionein domain superfamily	Homologous Superfamily
A	IPR018064	Metallothionein, vertebrate, metal binding site	Binding Site
A	IPR000006	Metallothionein, vertebrate	Family
A	IPR023587	Metallothionein domain superfamily, vertebrate	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.