2LYC | pdb_00002lyc

Structure of C-terminal domain of Ska1

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	SKA1_C	e2lycA1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: SKA1_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.10.1890	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Ska1 microtubule binding domain-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF07160	Spindle and kinetochore-associated protein 1 (SKA1)	Spindle and kinetochore-associated protein 1	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Spindle and kinetochore-associated protein 1 homolog	cytoskeletal protein binding microtubule binding protein binding binding tubulin binding	cellular process cell cycle mitotic cell cycle regulation of cytoskeleton organization regulation of microtubule polymerization or depolymerization regulation of biological process regulation of cellular component organization regulation of cellular process microtubule cytoskeleton organization biological regulation regulation of microtubule-based process regulation of organelle organization cellular component organization organelle organization cellular process cell cycle mitotic cell cycle regulation of cytoskeleton organization regulation of microtubule polymerization or depolymerization regulation of biological process regulation of cellular component organization regulation of cellular process microtubule cytoskeleton organization biological regulation regulation of microtubule-based process regulation of organelle organization cellular component organization organelle organization microtubule polymerization or depolymerization microtubule-based process cellular component organization or biogenesis cytoskeleton organization regulation of microtubule cytoskeleton organization establishment of organelle localization cellular localization mitotic metaphase chromosome alignment metaphase chromosome alignment localization chromosome localization organelle localization establishment of localization in cell mitotic sister chromatid segregation chromosome segregation cell cycle process mitotic nuclear division attachment of spindle microtubules to kinetochore organelle fission attachment of mitotic spindle microtubules to kinetochore chromosome organization sister chromatid segregation establishment of localization nuclear division mitotic cell cycle process nuclear chromosome segregation establishment of chromosome localization cell division regulation of cell cycle process regulation of attachment of spindle microtubules to kinetochore regulation of cell cycle	intracellular anatomical structure intracellular membraneless organelle chromosome chromosomal region kinetochore intracellular organelle cellular anatomical structure organelle membraneless organelle chromosome, centromeric region condensed chromosome, centromeric region supramolecular complex condensed chromosome polymeric cytoskeletal fiber intracellular anatomical structure intracellular membraneless organelle chromosome chromosomal region kinetochore intracellular organelle cellular anatomical structure organelle membraneless organelle chromosome, centromeric region condensed chromosome, centromeric region supramolecular complex condensed chromosome polymeric cytoskeletal fiber spindle spindle microtubule cytoskeleton supramolecular fiber microtubule supramolecular polymer microtubule cytoskeleton cytoplasm mitotic spindle protein-containing complex outer kinetochore meiotic spindle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR009829	Spindle and kinetochore-associated protein 1	Family
A	IPR042031	SKA1 microtubule binding domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.