2LM9 | pdb_00002lm9

The NMR structure of a major allergen from dust mite

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Blo t 5 dust mite allergen-like	8046819	4005314	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Blo t 5 dust mite allergen-like	8053433	3002185	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Blo-t-5	e2lm9A1	A: alpha bundles	X: YvfG-like	H: Mite allergen Der p 5-related (From Topology)	T: Mite allergen Der p 5-related	F: Blo-t-5	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.58.970	Mainly Alpha	Up-down Bundle	Methane Monooxygenase Hydroxylase	Chain G, domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF11642	Mite allergen Blo t 5 (Blo-t-5)	Mite allergen Blo t 5	This family of proteins is Blo t 5, an allergen protein from Blomia tropicalis mites. This protein shoes strong reactivity with IgE in asthmatic and rhinitis patients.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Blo t 21 allergen	identical protein binding protein binding binding protein homodimerization activity protein dimerization activity IgE binding protein-containing complex binding immunoglobulin binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR038455	Mite allergen, group 5/21 superfamily	Homologous Superfamily
A	IPR020306	Mite allergen, group 5/21	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.