2KS6

NMR solution structure of ALG13 --- obtained with iterative CS-Rosetta from backbone NMR data.

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Glyco_tran_28_C	e2ks6A1	A: a/b three-layered sandwiches	X: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	H: UDP-Glycosyltransferase/glycogen phosphorylase (From Topology)	T: UDP-Glycosyltransferase/glycogen phosphorylase	F: Glyco_tran_28_C	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.2000	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Glycogen Phosphorylase B	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF04101	Glycosyltransferase family 28 C-terminal domain (Glyco_tran_28_C)	Glycosyltransferase family 28 C-terminal domain	The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (Swiss:P93115, EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (Swiss:P74657, EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcN ...	The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (Swiss:P93115, EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (Swiss:P74657, EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	UDP-N-acetylglucosamine transferase subunit ALG13	UDP-glycosyltransferase activity glycosyltransferase activity N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity acetylglucosaminyltransferase activity transferase activity hexosyltransferase activity catalytic activity identical protein binding protein binding binding	carbohydrate derivative biosynthetic process dolichol-linked oligosaccharide biosynthetic process glycoprotein biosynthetic process carbohydrate derivative metabolic process primary metabolic process glycoprotein metabolic process protein N-linked glycosylation protein glycosylation macromolecule biosynthetic process protein N-linked glycosylation via asparagine biosynthetic process glycosylation macromolecule modification macromolecule glycosylation carbohydrate derivative biosynthetic process dolichol-linked oligosaccharide biosynthetic process glycoprotein biosynthetic process carbohydrate derivative metabolic process primary metabolic process glycoprotein metabolic process protein N-linked glycosylation protein glycosylation macromolecule biosynthetic process protein N-linked glycosylation via asparagine biosynthetic process glycosylation macromolecule modification macromolecule glycosylation metabolic process cellular process protein metabolic process macromolecule metabolic process protein modification process	membrane-bounded organelle Golgi membrane intracellular anatomical structure Golgi apparatus cytoplasmic side of membrane membrane cytoplasmic side of Golgi membrane intracellular membrane-bounded organelle endomembrane system side of membrane intracellular organelle cellular anatomical structure bounding membrane of organelle organelle membrane-bounded organelle Golgi membrane intracellular anatomical structure Golgi apparatus cytoplasmic side of membrane membrane cytoplasmic side of Golgi membrane intracellular membrane-bounded organelle endomembrane system side of membrane intracellular organelle cellular anatomical structure bounding membrane of organelle organelle cytoplasm organelle membrane cytosol protein-containing complex catalytic complex organelle subcompartment membrane protein complex transferase complex transferase complex, transferring phosphorus-containing groups endoplasmic reticulum subcompartment nuclear outer membrane-endoplasmic reticulum membrane network endoplasmic reticulum UDP-N-acetylglucosamine transferase complex endoplasmic reticulum protein-containing complex endoplasmic reticulum membrane nucleus

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR052474	UDP-N-acetylglucosamine transferase subunit	Family
A	IPR007235	Glycosyl transferase, family 28, C-terminal	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.