2JI6
X-ray structure of Oxalyl-CoA decarboxylase in complex with 3-deaza- ThDP and oxalyl-CoA
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B | SCOP2B Superfamily | DHS-like NAD/FAD-binding domain | 8034661 | 3001728 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Thiamin diphosphate-binding fold (THDP-binding) | 8034663 | 3001790 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Thiamin diphosphate-binding fold (THDP-binding) | 8034662 | 3001790 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | DHS-like NAD/FAD-binding domain | 8034661 | 3001728 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Thiamin diphosphate-binding fold (THDP-binding) | 8034662 | 3001790 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Thiamin diphosphate-binding fold (THDP-binding) | 8034663 | 3001790 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | TPP_enzyme_M | e2ji6B1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: DHS-like NAD/FAD-binding domain | F: TPP_enzyme_M | ECOD (1.6) |
B | TPP_enzyme_C | e2ji6B3 | A: a/b three-layered sandwiches | X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | T: Thiamin diphosphate-binding fold (THDP-binding) | F: TPP_enzyme_C | ECOD (1.6) |
B | TPP_enzyme_N | e2ji6B2 | A: a/b three-layered sandwiches | X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | T: Thiamin diphosphate-binding fold (THDP-binding) | F: TPP_enzyme_N | ECOD (1.6) |
A | TPP_enzyme_M | e2ji6A1 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: DHS-like NAD/FAD-binding domain | F: TPP_enzyme_M | ECOD (1.6) |
A | TPP_enzyme_C | e2ji6A3 | A: a/b three-layered sandwiches | X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | T: Thiamin diphosphate-binding fold (THDP-binding) | F: TPP_enzyme_C | ECOD (1.6) |
A | TPP_enzyme_N | e2ji6A2 | A: a/b three-layered sandwiches | X: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | H: Thiamin diphosphate-binding fold (THDP-binding) (From Topology) | T: Thiamin diphosphate-binding fold (THDP-binding) | F: TPP_enzyme_N | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 3.40.50.970 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | CATH (4.3.0) |
B | 3.40.50.1220 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | TPP-binding domain | CATH (4.3.0) |
A | 3.40.50.970 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains | CATH (4.3.0) |
A | 3.40.50.1220 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | TPP-binding domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00205 | Thiamine pyrophosphate enzyme, central domain (TPP_enzyme_M) | Thiamine pyrophosphate enzyme, central domain | The central domain of TPP enzymes contains a 2-fold Rossman fold. | Domain | |
PF02775 | Thiamine pyrophosphate enzyme, C-terminal TPP binding domain (TPP_enzyme_C) | Thiamine pyrophosphate enzyme, C-terminal TPP binding domain | - | Domain | |
PF02776 | Thiamine pyrophosphate enzyme, N-terminal TPP binding domain (TPP_enzyme_N) | Thiamine pyrophosphate enzyme, N-terminal TPP binding domain | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR017660 | Oxalyl-CoA decarboxylase | Family | |
IPR012001 | Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain | Domain | |
IPR012000 | Thiamine pyrophosphate enzyme, central domain | Domain | |
IPR029061 | Thiamin diphosphate-binding fold | Homologous Superfamily | |
IPR045025 | TPP-binding domain containing protein HACL1-like | Family | |
IPR029035 | DHS-like NAD/FAD-binding domain superfamily | Homologous Superfamily | |
IPR011766 | Thiamine pyrophosphate enzyme, TPP-binding | Domain |