2BHM

Crystal structure of VirB8 from Brucella suis

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2bhma1	Alpha and beta proteins (a+b)	Cystatin-like	NTF2-like	VirB8-like	Type IV secretion system protein VirB8	BRUCELLA SUIS (Brucella suis ) [TaxId: 29461 ],	SCOPe (2.08)
B	d2bhmb_	Alpha and beta proteins (a+b)	Cystatin-like	NTF2-like	VirB8-like	Type IV secretion system protein VirB8	BRUCELLA SUIS (Brucella suis ) [TaxId: 29461 ],	SCOPe (2.08)
D	d2bhmd_	Alpha and beta proteins (a+b)	Cystatin-like	NTF2-like	VirB8-like	Type IV secretion system protein VirB8	BRUCELLA SUIS (Brucella suis ) [TaxId: 29461 ],	SCOPe (2.08)
E	d2bhme_	Alpha and beta proteins (a+b)	Cystatin-like	NTF2-like	VirB8-like	Type IV secretion system protein VirB8	BRUCELLA SUIS (Brucella suis ) [TaxId: 29461 ],	SCOPe (2.08)
C	d2bhmc_	Alpha and beta proteins (a+b)	Cystatin-like	NTF2-like	VirB8-like	Type IV secretion system protein VirB8	BRUCELLA SUIS (Brucella suis ) [TaxId: 29461 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	VirB8-like	8021171	4001668	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	NTF2-like	8033551	3000472	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	NTF2-like	8033551	3000472	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	NTF2-like	8033551	3000472	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	NTF2-like	8033551	3000472	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	NTF2-like	8033551	3000472	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	VirB8	e2bhmA1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: VirB8	ECOD (1.6)
B	VirB8	e2bhmB1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: VirB8	ECOD (1.6)
D	VirB8	e2bhmD1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: VirB8	ECOD (1.6)
E	VirB8	e2bhmE1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: VirB8	ECOD (1.6)
C	VirB8	e2bhmC1	A: a+b two layers	X: Cystatin-like	H: NTF2-like (From Topology)	T: NTF2-like	F: VirB8	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.10.450.230	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
B	3.10.450.230	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
D	3.10.450.230	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
E	3.10.450.230	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
C	3.10.450.230	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E	TYPE IV SECRETION SYSTEM PROTEIN VIRB8	identical protein binding protein binding binding	protein localization establishment of protein localization cellular localization nitrogen compound transport transport secretion establishment of protein localization to extracellular region export from cell protein secretion establishment of localization protein localization to extracellular region transmembrane transport localization secretion by cell protein transmembrane transport protein localization establishment of protein localization cellular localization nitrogen compound transport transport secretion establishment of protein localization to extracellular region export from cell protein secretion establishment of localization protein localization to extracellular region transmembrane transport localization secretion by cell protein transmembrane transport protein transport protein secretion by the type IV secretion system cellular macromolecule localization macromolecule localization cellular process secretion by the type IV secretion system	cell periphery cellular anatomical structure plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E	IPR032710	NTF2-like domain superfamily	Homologous Superfamily
A, B, C, D, E	IPR007430	Bacterial virulence protein VirB8	Domain
A, B, C, D, E	IPR026264	Type IV secretion system protein VirB8/PtlE	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.