2A6O | pdb_00002a6o

Crystal Structure of the ISHp608 Transposase in Complex with Stem-loop DNA

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
C [auth A]	d2a6oa_	Alpha and beta proteins (a+b)	Ferredoxin-like	Transposase IS200-like	Transposase IS200-like	ISHP608 transposase	(Helicobacter pylori ) [TaxId: 210 ],	SCOPe (2.08)
D [auth B]	d2a6ob_	Alpha and beta proteins (a+b)	Ferredoxin-like	Transposase IS200-like	Transposase IS200-like	ISHP608 transposase	(Helicobacter pylori ) [TaxId: 210 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C [auth A]	SCOP2B Superfamily	Transposase IS200-like	8037527	3001347	SCOP2B (2022-06-29)
D [auth B]	SCOP2B Superfamily	Transposase IS200-like	8037527	3001347	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C [auth A]	Y1_Tnp	e2a6oA1	A: a+b two layers	X: Alpha-beta plaits	H: Origin of replication-binding domains	T: Transposase IS200-like	F: Y1_Tnp	ECOD (1.6)
D [auth B]	Y1_Tnp	e2a6oB1	A: a+b two layers	X: Alpha-beta plaits	H: Origin of replication-binding domains	T: Transposase IS200-like	F: Y1_Tnp	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C [auth A]	3.30.70.1290	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Transposase IS200-like	CATH (4.3.0)
D [auth B]	3.30.70.1290	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	Transposase IS200-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C [auth A], D [auth B]	PF01797	Transposase IS200 like (Y1_Tnp)	Transposase IS200 like	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth C], B [auth D]	5'-D(CPCPCPCPTPAPGPCPTPTPTPAPGPCPTPAPTPGPGPGPGPA)-3'	-	-	-
C [auth A], D [auth B]	ISHp608 Transposase	DNA binding binding nucleic acid binding cation binding ion binding metal ion binding small molecule binding transposase activity catalytic activity, acting on DNA catalytic activity, acting on a nucleic acid catalytic activity	nucleobase-containing compound metabolic process DNA recombination cellular process metabolic process primary metabolic process DNA metabolic process macromolecule metabolic process transposition DNA transposition nucleic acid metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C [auth A], D [auth B]	IPR036515	Transposase IS200-like superfamily	Homologous Superfamily
C [auth A], D [auth B]	IPR002686	Transposase IS200-like	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.