Annotations: 1R95

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1r95a_	All beta proteins	HesB-like domain	HesB-like domain	HesB-like domain	Fe-S scaffold protein IscA (YfhF)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)
B	d1r95b_	All beta proteins	HesB-like domain	HesB-like domain	HesB-like domain	Fe-S scaffold protein IscA (YfhF)	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	HesB-like domain	8040456	3001923	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	HesB-like domain	8040456	3001923	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Fe-S_biosyn	e1r95A1	A: beta complex topology	X: HesB-like domain (From Topology)	H: HesB-like domain (From Topology)	T: HesB-like domain	F: Fe-S_biosyn	ECOD (1.6)
B	Fe-S_biosyn	e1r95B1	A: beta complex topology	X: HesB-like domain (From Topology)	H: HesB-like domain (From Topology)	T: HesB-like domain	F: Fe-S_biosyn	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.300.12	Mainly Beta	Sandwich	Hypothetical Protein Aq_1857	Chain: A	CATH (4.3.0)
B	2.60.300.12	Mainly Beta	Sandwich	Hypothetical Protein Aq_1857	Chain: A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF01521	Iron-sulphur cluster biosynthesis (Fe-S_biosyn)	Iron-sulphur cluster biosynthesis	This family is involved in iron-sulphur cluster biosynthesis [3]. Its members include proteins that are involved in nitrogen fixation such as the HesB and HesB-like proteins [1] [2].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Protein yfhF	cation binding transition metal ion binding iron ion binding ion binding binding ferrous iron binding metal ion binding small molecule binding iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding metal cluster binding metallochaperone activity iron chaperone activity molecular carrier activity	cellular component biogenesis cellular component organization metallo-sulfur cluster assembly cellular component assembly iron-sulfur cluster assembly cellular process cellular component organization or biogenesis	protein-containing complex iron-sulfur cluster transfer complex catalytic complex transferase complex cellular anatomical structure intracellular anatomical structure cytoplasm cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR035903	HesB-like domain superfamily	Homologous Superfamily
A, B	IPR016092	FeS cluster insertion protein	Family
A, B	IPR000361	FeS cluster biogenesis	Domain
A, B	IPR050322	Iron-sulfur cluster assembly and transfer HesB/IscA	Family
A, B	IPR017870	FeS cluster insertion, C-terminal, conserved site	Conserved Site
A, B	IPR011302	Iron-binding protein IscA, proteobacteria	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.