1K73

Co-crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
D	d1k73d_	All beta proteins	Reductase/isomerase/elongation factor common domain	Translation proteins	Ribosomal protein L3	Ribosomal protein L3	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
E	d1k73e_	Alpha and beta proteins (a/b)	Ribosomal protein L4	Ribosomal protein L4	Ribosomal protein L4	Ribosomal protein L4	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
G	d1k73g1	Alpha and beta proteins (a+b)	Ribosomal protein L6	Ribosomal protein L6	Ribosomal protein L6	Ribosomal protein L6	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
I	d1k73i_	Peptides	Ribosomal protein L10	Ribosomal protein L10	Ribosomal protein L10	Ribosomal protein L10	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
J	d1k73j_	Alpha and beta proteins (a+b)	alpha/beta-Hammerhead	Ribosomal protein L16p/L10e	Ribosomal protein L10e	Ribosomal protein L10e	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
K	d1k73k_	Alpha and beta proteins (a/b)	Ribosomal protein L13	Ribosomal protein L13	Ribosomal protein L13	Ribosomal protein L13	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
L	d1k73l_	All beta proteins	Ribosomal protein L14	Ribosomal protein L14	Ribosomal protein L14	Ribosomal protein L14	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
O	d1k73o_	Alpha and beta proteins (a/b)	Ribonuclease H-like motif	Translational machinery components	Ribosomal protein L18 and S11	Ribosomal protein L18 (L18p)	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
P	d1k73p_	Alpha and beta proteins (a/b)	Ribosomal proteins L15p and L18e	Ribosomal proteins L15p and L18e	Ribosomal proteins L15p and L18e	Ribosomal protein L18e	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
T	d1k73t_	Alpha and beta proteins (a+b)	Ribosomal proteins S24e, L23 and L15e	Ribosomal proteins S24e, L23 and L15e	L23p	Ribosomal protein L23	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
V	d1k73v_	Small proteins	Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	Ribosomal protein L24e	Ribosomal protein L24e	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
X	d1k73x_	Alpha and beta proteins (a+b)	Ribosomal protein L30p/L7e	Ribosomal protein L30p/L7e	Ribosomal protein L30p/L7e	Archaeal L30 (L30a)	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
Y	d1k73y_	Alpha and beta proteins (a+b)	Ribosomal protein L31e	Ribosomal protein L31e	Ribosomal protein L31e	Ribosomal protein L31e	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
Z	d1k73z_	Alpha and beta proteins (a/b)	Barstar-like	Ribosomal protein L32e	Ribosomal protein L32e	Ribosomal protein L32e	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
AA [auth 1]	d1k731_	Small proteins	Rubredoxin-like	Zn-binding ribosomal proteins	Ribosomal protein L37ae	Ribosomal protein L37ae	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
DA [auth 4]	d1k734_	Small proteins	Rubredoxin-like	Zn-binding ribosomal proteins	Ribosomal protein L44e	Ribosomal protein L44e	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
M	d1k73m_	Alpha and beta proteins (a/b)	Ribosomal proteins L15p and L18e	Ribosomal proteins L15p and L18e	Ribosomal proteins L15p and L18e	Ribosomal protein L15 (L15p)	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
N	d1k73n_	Alpha and beta proteins (a+b)	Ribosomal proteins S24e, L23 and L15e	Ribosomal proteins S24e, L23 and L15e	L15e	Ribosomal protein L15e	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
Q	d1k73q_	All alpha proteins	Ribosomal protein L19 (L19e)	Ribosomal protein L19 (L19e)	Ribosomal protein L19 (L19e)	Ribosomal protein L19 (L19e)	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
R	d1k73r_	All beta proteins	SH3-like barrel	Translation proteins SH3-like domain	Ribosomal proteins L24p and L21e	Ribosomal proteins L21e	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
S	d1k73s_	Alpha and beta proteins (a+b)	Ribosomal protein L22	Ribosomal protein L22	Ribosomal protein L22	Ribosomal protein L22	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
U	d1k73u_	All beta proteins	SH3-like barrel	Translation proteins SH3-like domain	Ribosomal proteins L24p and L21e	Ribosomal proteins L24 (L24p)	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
W	d1k73w_	All alpha proteins	Long alpha-hairpin	Ribosomal protein L29 (L29p)	Ribosomal protein L29 (L29p)	Ribosomal protein L29 (L29p)	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
BA [auth 2]	d1k732_	Small proteins	Rubredoxin-like	Zn-binding ribosomal proteins	Ribosomal protein L37e	Ribosomal protein L37e	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
CA [auth 3]	d1k733_	All alpha proteins	Non-globular all-alpha subunits of globular proteins	Ribosomal protein L39e	Ribosomal protein L39e	Ribosomal protein L39e	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
C	d1k73c1	All beta proteins	SH3-like barrel	Translation proteins SH3-like domain	C-terminal domain of ribosomal protein L2	C-terminal domain of ribosomal protein L2	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
C	d1k73c2	All beta proteins	OB-fold	Nucleic acid-binding proteins	Cold shock DNA-binding domain-like	N-terminal domain of ribosomal protein L2	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
F	d1k73f_	Alpha and beta proteins (a+b)	RL5-like	RL5-like	Ribosomal protein L5	Ribosomal protein L5	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)
H	d1k73h_	Alpha and beta proteins (a+b)	Bacillus chorismate mutase-like	L30e-like	L30e/L7ae ribosomal proteins	Ribosomal protein L7ae	(Haloarcula marismortui ) [TaxId: 2238 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
D	SCOP2B Superfamily	Translational proteins	8032615	3000811	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Ribosomal protein L4	8032619	3001146	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Ribosomal protein L6	8032625	3000724	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Ribosomal protein L6	8032623	3000724	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Ribosomal protein L16p/L10e	8035022	3000884	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	Ribosomal protein L13	8032632	3001134	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	50S Ribosomal protein L14-like	8034442	3000433	SCOP2B (2022-06-29)
O	SCOP2B Superfamily	Translational machinery components	8032638	3000571	SCOP2B (2022-06-29)
P	SCOP2B Superfamily	Ribosomal proteins L15p and L18e	8032640	3001045	SCOP2B (2022-06-29)
T	SCOP2B Superfamily	Ribosomal proteins S24e, L23 and L15e	8032646	3000210	SCOP2B (2022-06-29)
V	SCOP2B Superfamily	Glucocorticoid receptor-like (DNA-binding domain)	8032651	3000068	SCOP2B (2022-06-29)
X	SCOP2B Superfamily	Ribosomal protein L30p/L7e	8032657	3001378	SCOP2B (2022-06-29)
Y	SCOP2B Superfamily	Ribosomal protein L31e	8032659	3000699	SCOP2B (2022-06-29)
Z	SCOP2B Superfamily	Ribosomal protein L32e	8032660	3000982	SCOP2B (2022-06-29)
AA [auth 1]	SCOP2B Superfamily	Zn-binding ribosomal proteins	8032661	3001320	SCOP2B (2022-06-29)
DA [auth 4]	SCOP2B Superfamily	Zn-binding ribosomal proteins	8032610	3001320	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	Ribosomal proteins L15p and L18e	8032635	3001045	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	Ribosomal proteins S24e, L23 and L15e	8032636	3000210	SCOP2B (2022-06-29)
Q	SCOP2B Superfamily	Ribosomal protein L19 (L19e)	8032641	3000890	SCOP2B (2022-06-29)
R	SCOP2B Superfamily	Translation proteins SH3-like KOW motif containing domain	8032644	3000334	SCOP2B (2022-06-29)
S	SCOP2B Superfamily	Ribosomal protein L22	8032645	3001078	SCOP2B (2022-06-29)
U	SCOP2B Superfamily	Translation proteins SH3-like KOW motif containing domain	8032648	3000334	SCOP2B (2022-06-29)
W	SCOP2B Superfamily	Ribosomal protein L29 (L29p)	8032653	3000713	SCOP2B (2022-06-29)
BA [auth 2]	SCOP2B Superfamily	Zn-binding ribosomal proteins	8032609	3001320	SCOP2B (2022-06-29)
CA [auth 3]	SCOP2B Superfamily	Ribosomal protein L39e	8034428	3001756	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Nucleic acid-binding proteins	8032613	3000135	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Translation proteins SH3-like KOW motif containing domain	8032612	3000334	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	RL5-like	8032620	3001709	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	L30e-like	8032628	3001739	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
D	Ribosomal_L3	e1k73D1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: Alanine racemase-C	F: Ribosomal_L3	ECOD (1.6)
E	Ribosomal_L4	e1k73E1	A: a/b three-layered sandwiches	X: Ribosomal protein L4 (From Topology)	H: Ribosomal protein L4 (From Topology)	T: Ribosomal protein L4	F: Ribosomal_L4	ECOD (1.6)
G	Ribosomal_L6_2	e1k73G2	A: a+b two layers	X: Ribosomal protein L6 (From Topology)	H: Ribosomal protein L6 (From Topology)	T: Ribosomal protein L6	F: Ribosomal_L6_2	ECOD (1.6)
G	Ribosomal_L6	e1k73G1	A: a+b two layers	X: Ribosomal protein L6 (From Topology)	H: Ribosomal protein L6 (From Topology)	T: Ribosomal protein L6	F: Ribosomal_L6	ECOD (1.6)
I	rplP0_like	e1k73I1	A: a+b two layers	X: Alpha-beta plaits	H: Ribosomal protein L10-like (From Topology)	T: Ribosomal protein L10-like	F: rplP0_like	ECOD (1.6)
J	Ribosomal_L16	e1k73J1	A: a+b complex topology	X: alpha/beta-Hammerhead/Barrel-sandwich hybrid	H: alpha/beta-Hammerhead/Barrel-sandwich hybrid	T: Ribosomal protein L10e	F: Ribosomal_L16	ECOD (1.6)
K	Ribosomal_L13	e1k73K1	A: a/b three-layered sandwiches	X: Ribosomal protein L13/L15p/L18e/L32e	H: Ribosomal protein L13 and L16-A (From Topology)	T: Ribosomal protein L13 and L16-A	F: Ribosomal_L13	ECOD (1.6)
L	Ribosomal_L14	e1k73L1	A: beta barrels	X: Ribosomal protein L14-like	H: Ribosomal protein L14-related (From Topology)	T: Ribosomal protein L14-related	F: Ribosomal_L14	ECOD (1.6)
O	Ribosomal_L5e	e1k73O1	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: Ribosomal_L5e	ECOD (1.6)
P	Ribosomal_L18	e1k73P1	A: a/b three-layered sandwiches	X: Ribosomal protein L13/L15p/L18e/L32e	H: Ribosomal proteins L15p and L18e (From Topology)	T: Ribosomal proteins L15p and L18e	F: Ribosomal_L18	ECOD (1.6)
T	Ribosomal_L23_1	e1k73T1	A: a+b two layers	X: Alpha-beta plaits	H: Ribosomal proteins S24e, L23 and L15e (From Topology)	T: Ribosomal proteins S24e, L23 and L15e	F: Ribosomal_L23_1	ECOD (1.6)
V	Ribosomal_L24e	e1k73V1	A: few secondary structure elements	X: Glucocorticoid receptor-like	H: LIM domain-like	T: LIM domain-like	F: Ribosomal_L24e	ECOD (1.6)
X	Ribosomal_L30_1	e1k73X1	A: a+b two layers	X: Ribosomal protein L30p/L7e (From Topology)	H: Ribosomal protein L30p/L7e (From Topology)	T: Ribosomal protein L30p/L7e	F: Ribosomal_L30_1	ECOD (1.6)
Y	Ribosomal_L31e	e1k73Y1	A: a+b two layers	X: Ribosomal protein L31e-like	H: Ribosomal protein L31e/gp120 outer domain (From Topology)	T: Ribosomal protein L31e/gp120 outer domain	F: Ribosomal_L31e	ECOD (1.6)
Z	Ribosomal_L32e	e1k73Z1	A: a/b three-layered sandwiches	X: Ribosomal protein L13/L15p/L18e/L32e	H: Ribosomal protein L32e (From Topology)	T: Ribosomal protein L32e	F: Ribosomal_L32e	ECOD (1.6)
AA [auth 1]	Ribosomal_L37ae	e1k7311	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: Ribosomal_L37ae	ECOD (1.6)
DA [auth 4]	Ribosomal_L44	e1k7341	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: Ribosomal_L44	ECOD (1.6)
M	Ribosomal_L18	e1k73M1	A: a/b three-layered sandwiches	X: Ribosomal protein L13/L15p/L18e/L32e	H: Ribosomal proteins L15p and L18e (From Topology)	T: Ribosomal proteins L15p and L18e	F: Ribosomal_L18	ECOD (1.6)
N	Ribosomal_L15e	e1k73N1	A: a+b two layers	X: Alpha-beta plaits	H: Ribosomal proteins S24e, L23 and L15e (From Topology)	T: Ribosomal proteins S24e, L23 and L15e	F: Ribosomal_L15e	ECOD (1.6)
Q	Ribosomal_L19e_N	e1k73Q1	A: alpha arrays	X: Ribosomal protein L19 (L19e) N-terminal domain (From Topology)	H: Ribosomal protein L19 (L19e) N-terminal domain (From Topology)	T: Ribosomal protein L19 (L19e) N-terminal domain	F: Ribosomal_L19e_N	ECOD (1.6)
Q	Ribosomal_L19e_C	e1k73Q2	A: alpha bundles	X: Ribosomal protein L19 (L19e) C-terminal domain (From Topology)	H: Ribosomal protein L19 (L19e) C-terminal domain (From Topology)	T: Ribosomal protein L19 (L19e) C-terminal domain	F: Ribosomal_L19e_C	ECOD (1.6)
R	Ribosomal_L21e	e1k73R1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: Ribosomal_L21e	ECOD (1.6)
S	Ribosomal_L22	e1k73S1	A: a+b two layers	X: Enolase-N/ribosomal protein	H: Ribosomal protein L22 (From Topology)	T: Ribosomal protein L22	F: Ribosomal_L22	ECOD (1.6)
U	Ribosomal_L26	e1k73U1	A: beta barrels	X: SH3	H: SH3	T: SH3	F: Ribosomal_L26	ECOD (1.6)
W	Ribosomal_L29	e1k73W1	A: alpha bundles	X: Long alpha-hairpin	H: Ribosomal protein L29 (L29p) (From Topology)	T: Ribosomal protein L29 (L29p)	F: Ribosomal_L29	ECOD (1.6)
BA [auth 2]	Ribosomal_L37e	e1k7321	A: few secondary structure elements	X: Rubredoxin-like	H: Rubredoxin-related	T: Rubredoxin-related	F: Ribosomal_L37e	ECOD (1.6)
CA [auth 3]	Ribosomal_L39	e1k7331	A: extended segments	X: Ribosomal protein L39e (From Topology)	H: Ribosomal protein L39e (From Topology)	T: Ribosomal protein L39e	F: Ribosomal_L39	ECOD (1.6)
C	Ribosomal_L2_1	e1k73C1	A: beta barrels	X: OB-fold	H: Nucleic acid-binding proteins (From Topology)	T: Nucleic acid-binding proteins	F: Ribosomal_L2_1	ECOD (1.6)
C	Ribosomal_L2_C_2	e1k73C2	A: beta barrels	X: SH3	H: SH3	T: SH3	F: Ribosomal_L2_C_2	ECOD (1.6)
F	Ribosomal_L5_C	e1k73F1	A: a+b two layers	X: Ribosomal protein L5 (From Topology)	H: Ribosomal protein L5 (From Topology)	T: Ribosomal protein L5	F: Ribosomal_L5_C	ECOD (1.6)
H	Ribosomal_L7Ae_1	e1k73H1	A: a+b three layers	X: Bacillus chorismate mutase-like	H: L30e-like (From Topology)	T: L30e-like	F: Ribosomal_L7Ae_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
D	2.40.30.10	Mainly Beta	Beta Barrel	Elongation Factor Tu (Ef-tu)	domain 3	CATH (4.3.0)
D	3.30.1430.10	Alpha Beta	2-Layer Sandwich	Ribosomal Protein L3	Chain: B	CATH (4.3.0)
D	4.10.960.10	Few Secondary Structures	Irregular	Ribosomal protein L3	domain 3	CATH (4.3.0)
E	3.40.1370.10	Alpha Beta	3-Layer(aba) Sandwich	Ribosomal Protein L4	Chain: A	CATH (4.3.0)
G	3.90.930.12	Alpha Beta	Alpha-Beta Complex	Outer Surface Protein A	domain 3	CATH (4.3.0)
J	3.90.1170.10	Alpha Beta	Alpha-Beta Complex	Aldehyde Oxidoreductase	domain 3	CATH (4.3.0)
K	3.90.1180.10	Alpha Beta	Alpha-Beta Complex	Ribosomal Protein L13p	Chain: A	CATH (4.3.0)
L	2.40.150.20	Mainly Beta	Beta Barrel	Ribosomal Protein L14	Ribosomal protein L14/L23	CATH (4.3.0)
O	3.30.420.100	Alpha Beta	2-Layer Sandwich	Nucleotidyltransferase	domain 5	CATH (4.3.0)
P	3.100.10.10	Alpha Beta	Ribosomal Protein L15	Chain: K	domain 2	CATH (4.3.0)
T	3.30.70.330	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	RRM (RNA recognition motif) domain	CATH (4.3.0)
V	2.30.170.20	Mainly Beta	Roll	Ribosomal Protein L24e	Chain: T	CATH (4.3.0)
X	3.30.1390.20	Alpha Beta	2-Layer Sandwich	Ribosomal Protein L30	Chain: A,	CATH (4.3.0)
X	1.10.15.30	Mainly Alpha	Orthogonal Bundle	3-methyladenine DNA Glycosylase II	Chain A, domain 3	CATH (4.3.0)
Y	3.10.440.10	Alpha Beta	Roll	Ribosomal Protein L31e	Chain: W	CATH (4.3.0)
AA [auth 1]	2.20.25.30	Mainly Beta	Single Sheet	N-terminal domain of TfIIb		CATH (4.3.0)
DA [auth 4]	3.10.450.80	Alpha Beta	Roll	Nuclear Transport Factor 2	Chain: A,	CATH (4.3.0)
M	4.10.990.10	Few Secondary Structures	Irregular	Molecule: Ribosomal Protein L15	Chain: K	CATH (4.3.0)
M	3.100.10.10	Alpha Beta	Ribosomal Protein L15	Chain: K	domain 2	CATH (4.3.0)
N	3.40.1120.10	Alpha Beta	3-Layer(aba) Sandwich	Ribosomal protein L15e	Ribosomal protein L15	CATH (4.3.0)
Q	1.10.1650.10	Mainly Alpha	Orthogonal Bundle	50s Ribosomal Protein L19e, Chain O, domain 1		CATH (4.3.0)
Q	1.10.1200.60	Mainly Alpha	Orthogonal Bundle	Non-ribosomal Peptide Synthetase Peptidyl Carrier Protein	Chain A	CATH (4.3.0)
Q	1.20.5.560	Mainly Alpha	Up-down Bundle	Single alpha-helices involved in coiled-coils or other helix-helix interfaces	Single Heli x bin	CATH (4.3.0)
R	2.30.30.70	Mainly Beta	Roll	SH3 type barrels.	Ribosomal protein L21	CATH (4.3.0)
S	3.90.470.10	Alpha Beta	Alpha-Beta Complex	Ribosomal Protein L22	Chain A	CATH (4.3.0)
U	2.30.30.30	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
W	1.10.287.310	Mainly Alpha	Orthogonal Bundle	Helix Hairpins		CATH (4.3.0)
BA [auth 2]	2.20.25.30	Mainly Beta	Single Sheet	N-terminal domain of TfIIb		CATH (4.3.0)
CA [auth 3]	1.10.1620.10	Mainly Alpha	Orthogonal Bundle	Atp Synthase Epsilon Chain	Chain: I	CATH (4.3.0)
C	2.30.30.30	Mainly Beta	Roll	SH3 type barrels.		CATH (4.3.0)
C	2.40.50.140	Mainly Beta	Beta Barrel	OB fold (Dihydrolipoamide Acetyltransferase, E2P)	Nucleic acid-binding proteins	CATH (4.3.0)
C	4.10.950.10	Few Secondary Structures	Irregular	Ribosomal protein L2	domain 3	CATH (4.3.0)
F	3.30.1440.10	Alpha Beta	2-Layer Sandwich	50s Ribosomal Protein L5	Chain: A,	CATH (4.3.0)
H	3.30.1330.30	Alpha Beta	2-Layer Sandwich	60s Ribosomal Protein L30	Chain: A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
D	PF00297	Ribosomal protein L3 (Ribosomal_L3)	Ribosomal protein L3	-	Family
E	PF00573	Ribosomal protein L4/L1 family (Ribosomal_L4)	Ribosomal protein L4/L1 family	-	Family
G	PF00347	Ribosomal protein L6 (Ribosomal_L6)	Ribosomal protein L6	-	Domain
J	PF00252	Ribosomal protein L16p/L10e (Ribosomal_L16)	Ribosomal protein L16p/L10e	-	Domain
K	PF00572	Ribosomal protein L13 (Ribosomal_L13)	Ribosomal protein L13	-	Family
L	PF00238	Ribosomal protein L14p/L23e (Ribosomal_L14)	Ribosomal protein L14p/L23e	-	Domain
O	PF17144	Ribosomal large subunit proteins 60S L5, and 50S L18 (Ribosomal_L5e)	Ribosomal large subunit proteins 60S L5, and 50S L18	-	Family
P	PF00828	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A (Ribosomal_L27A)	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	-	Family
T	PF00276	Ribosomal protein L23 (Ribosomal_L23)	Ribosomal protein L23	-	Family
X	PF00327	Ribosomal protein L30p/L7e (Ribosomal_L30)	Ribosomal protein L30p/L7e	This family includes prokaryotic L30 and eukaryotic L7.	Domain
Z	PF01655	Ribosomal protein L32 (Ribosomal_L32e)	Ribosomal protein L32	-	Family
AA [auth 1]	PF01780	Ribosomal L37ae protein family (Ribosomal_L37ae)	Ribosomal L37ae protein family	-	Family
DA [auth 4]	PF00935	Ribosomal protein L44 (Ribosomal_L44)	Ribosomal protein L44	-	Family
M	PF00828	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A (Ribosomal_L27A)	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	-	Family
N	PF00827	Ribosomal L15 (Ribosomal_L15e)	Ribosomal L15	-	Family
Q	PF01280	Ribosomal protein L19e (Ribosomal_L19e)	Ribosomal protein L19e	-	Family
R	PF01157	Ribosomal protein L21e (Ribosomal_L21e)	Ribosomal protein L21e	-	Family
S	PF00237	Ribosomal protein L22p/L17e (Ribosomal_L22)	Ribosomal protein L22p/L17e	This family includes L22 from prokaryotes and chloroplasts and L17 from eukaryotes.	Domain
U	PF16906	Ribosomal proteins L26 eukaryotic, L24P archaeal (Ribosomal_L26)	Ribosomal proteins L26 eukaryotic, L24P archaeal	-	Family
U	PF00467	KOW motif (KOW)	KOW motif	-	Family
W	PF00831	Ribosomal L29 protein (Ribosomal_L29)	Ribosomal L29 protein	-	Family
BA [auth 2]	PF01907	Ribosomal protein L37e (Ribosomal_L37e)	Ribosomal protein L37e	-	Family
CA [auth 3]	PF00832	Ribosomal L39 protein (Ribosomal_L39)	Ribosomal L39 protein	-	Family
C	PF03947	Ribosomal Proteins L2, C-terminal domain (Ribosomal_L2_C)	Ribosomal Proteins L2, C-terminal domain	-	Domain
C	PF00181	Ribosomal Proteins L2, RNA binding domain (Ribosomal_L2)	Ribosomal Proteins L2, RNA binding domain	-	Domain
F	PF00281	Ribosomal protein L5 (Ribosomal_L5)	Ribosomal protein L5	-	Domain
F	PF00673	ribosomal L5P family C-terminus (Ribosomal_L5_C)	ribosomal L5P family C-terminus	This region is found associated with Pfam:PF00281.	Domain
H	PF01248	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family (Ribosomal_L7Ae)	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD11 ...	This family includes: Ribosomal L7A from metazoa, Ribosomal L8-A and L8-B from fungi, 30S ribosomal protein HS6 from archaebacteria, 40S ribosomal protein S12 from eukaryotes, Ribosomal protein L30 from eukaryotes and archaebacteria. Gadd45 and MyD118 [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
D	RIBOSOMAL PROTEIN L3	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
E	RIBOSOMAL PROTEIN L4	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
G	RIBOSOMAL PROTEIN L6	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
I	RIBOSOMAL PROTEIN L10	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding large ribosomal subunit rRNA binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly cellular component organization or biogenesis ribosome assembly	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
J	RIBOSOMAL PROTEIN L10E	RNA binding binding organic cyclic compound binding tRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome rRNA binding	ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly cellular process cellular component organization or biogenesis ribosome assembly biosynthetic process metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
K	RIBOSOMAL PROTEIN L13	RNA binding binding organic cyclic compound binding nucleic acid binding mRNA binding structural molecule activity structural constituent of ribosome rRNA binding	regulation of cellular process negative regulation of biological process regulation of primary metabolic process post-transcriptional regulation of gene expression negative regulation of translation negative regulation of cellular process protein metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process regulation of protein metabolic process negative regulation of metabolic process biological regulation regulation of cellular process negative regulation of biological process regulation of primary metabolic process post-transcriptional regulation of gene expression negative regulation of translation negative regulation of cellular process protein metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process regulation of protein metabolic process negative regulation of metabolic process biological regulation primary metabolic process regulation of macromolecule metabolic process gene expression translation macromolecule biosynthetic process regulation of gene expression negative regulation of gene expression biosynthetic process negative regulation of biosynthetic process regulation of translation negative regulation of macromolecule biosynthetic process regulation of macromolecule biosynthetic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
L	RIBOSOMAL PROTEIN L14	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding large ribosomal subunit rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
O	RIBOSOMAL PROTEIN L18	RNA binding binding organic cyclic compound binding rRNA binding 5S rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly cellular process cellular component organization or biogenesis ribosome assembly biosynthetic process metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
P	RIBOSOMAL PROTEIN L18E	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
T	RIBOSOMAL PROTEIN L23	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly cellular process cellular component organization or biogenesis ribosome assembly biosynthetic process metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
V	RIBOSOMAL PROTEIN L24E	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding structural molecule activity structural constituent of ribosome RNA binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
X	RIBOSOMAL PROTEIN L30	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing cellular component biogenesis nucleobase-containing compound metabolic process RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process cellular component organization or biogenesis RNA processing rRNA metabolic process primary metabolic process gene expression nucleobase-containing compound biosynthetic process ribonucleoprotein complex biogenesis RNA metabolic process rRNA processing cellular component biogenesis nucleobase-containing compound metabolic process RNA biosynthetic process ribosome biogenesis nucleic acid biosynthetic process cellular component organization or biogenesis RNA processing rRNA metabolic process primary metabolic process gene expression nucleobase-containing compound biosynthetic process ribosomal large subunit biogenesis macromolecule biosynthetic process nucleic acid metabolic process maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) biosynthetic process cellular process metabolic process macromolecule metabolic process maturation of LSU-rRNA protein metabolic process translation	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
Y	RIBOSOMAL PROTEIN L31E	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
Z	RIBOSOMAL PROTEIN L32E	DNA binding binding organic cyclic compound binding nucleic acid binding nucleoside phosphate binding nucleotide binding heterocyclic compound binding small molecule binding RNA binding rRNA binding structural molecule activity structural constituent of ribosome	cellular response to stimulus response to stimulus primary metabolic process DNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process cellular response to stress DNA damage response response to stress metabolic process cellular process macromolecule metabolic process DNA repair biosynthetic process cellular response to stimulus response to stimulus primary metabolic process DNA metabolic process nucleic acid metabolic process nucleobase-containing compound metabolic process cellular response to stress DNA damage response response to stress metabolic process cellular process macromolecule metabolic process DNA repair biosynthetic process protein metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
AA [auth 1]	RIBOSOMAL PROTEIN L37Ae	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding structural molecule activity structural constituent of ribosome RNA binding organic cyclic compound binding rRNA binding nucleic acid binding large ribosomal subunit rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
DA [auth 4]	RIBOSOMAL PROTEIN L44E	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding RNA binding organic cyclic compound binding tRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome rRNA binding cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding RNA binding organic cyclic compound binding tRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome rRNA binding large ribosomal subunit rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
A	23S RRNA	-	-	-
M	RIBOSOMAL PROTEIN L15	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
N	RIBOSOMAL PROTEIN L15E	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
Q	RIBOSOMAL PROTEIN L19E	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding large ribosomal subunit rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
R	RIBOSOMAL PROTEIN L21E	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
S	RIBOSOMAL PROTEIN L22	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
B	5S RRNA	-	-	-
U	RIBOSOMAL PROTEIN L24	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis ribosomal large subunit biogenesis	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
W	RIBOSOMAL PROTEIN L29	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
BA [auth 2]	RIBOSOMAL PROTEIN L37E	cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding structural molecule activity structural constituent of ribosome RNA binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
CA [auth 3]	RIBOSOMAL PROTEIN L39E	structural molecule activity structural constituent of ribosome RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
C	RIBOSOMAL PROTEIN L2	RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
F	RIBOSOMAL PROTEIN L5	RNA binding binding organic cyclic compound binding tRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
H	RIBOSOMAL PROTEIN L7AE	RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding tRNA-specific ribonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity, acting on a tRNA nuclease activity RNA binding binding organic cyclic compound binding rRNA binding nucleic acid binding tRNA-specific ribonuclease activity endonuclease activity RNA endonuclease activity, producing 5'-phosphomonoesters catalytic activity, acting on RNA catalytic activity, acting on a nucleic acid RNA nuclease activity hydrolase activity catalytic activity, acting on a tRNA nuclease activity hydrolase activity, acting on ester bonds RNA endonuclease activity ribonuclease P activity endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters catalytic activity structural molecule activity structural constituent of ribosome	RNA metabolic process primary metabolic process gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process biosynthetic process tRNA processing RNA 5'-end processing metabolic process RNA metabolic process primary metabolic process gene expression nucleobase-containing compound biosynthetic process macromolecule biosynthetic process nucleic acid metabolic process tRNA metabolic process nucleobase-containing compound metabolic process RNA biosynthetic process nucleic acid biosynthetic process biosynthetic process tRNA processing RNA 5'-end processing metabolic process cellular process macromolecule metabolic process RNA processing tRNA 5'-leader removal tRNA 5'-end processing cellular component biogenesis ribosome biogenesis ribonucleoprotein complex biogenesis cellular component organization or biogenesis protein metabolic process translation	protein-containing complex ribonucleoprotein complex cellular anatomical structure intracellular anatomical structure cytoplasm intracellular organelle organelle membraneless organelle intracellular membraneless organelle ribosome

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
D	IPR019926	Large ribosomal subunit protein uL3, conserved site	Conserved Site
D	IPR019928	Large ribosomal subunit protein uL3, archaeal	Family
D	IPR009000	Translation protein, beta-barrel domain superfamily	Homologous Superfamily
D	IPR045077	Large ribosomal subunit protein uL3, archaeal/eukaryotic-type	Family
D	IPR044892	Ribosomal protein L3, domain 3, archaeal-type superfamily	Homologous Superfamily
D	IPR000597	Large ribosomal subunit protein uL3	Family
E	IPR019970	Large ribosomal subunit protein uL4, archaea	Family
E	IPR002136	Large ribosomal subunit protein uL4	Family
E	IPR013000	Large ribosomal subunit protein uL4, eukaryotic/archaeal, conserved site	Conserved Site
E	IPR045240	Large ribosomal subunit protein uL4, eukaryotic and archaeal type	Family
E	IPR023574	Large ribosomal subunit protein uL4 domain superfamily	Homologous Superfamily
G	IPR020040	Large ribosomal subunit protein uL6, alpha-beta domain	Domain
G	IPR019907	Large ribosomal subunit protein uL6, archaea	Family
G	IPR002359	Large ribosomal subunit protein uL6, conserved site-2	Conserved Site
G	IPR036789	Large ribosomal subunit protein uL6-like, alpha-beta domain superfamily	Homologous Superfamily
G	IPR000702	Large ribosomal subunit protein uL6-like	Family
I	IPR043141	Large ribosomal subunit protein uL10-like domain superfamily	Homologous Superfamily
I	IPR001790	Large ribosomal subunit protein uL10	Family
I	IPR043164	Large ribosomal subunit protein uL10-like, insertion domain superfamily	Homologous Superfamily
I	IPR050323	Universal ribosomal protein uL10	Family
I	IPR040637	Large ribosomal subunit protein uL10-like, insertion domain	Domain
I	IPR022909	Large ribosomal subunit protein uL10, archaea	Family
J	IPR036920	Large ribosomal subunit protein uL16 superfamily	Homologous Superfamily
J	IPR022981	Large ribosomal subunit protein uL16, archaea	Family
J	IPR001197	Large ribosomal subunit protein uL16, eukaryotes/archaea	Family
J	IPR016180	Large ribosomal subunit protein uL16 domain	Domain
J	IPR047873	Large ribosomal subunit protein uL16	Family
J	IPR018255	Large ribosomal subunit protein uL16, conserved site, eukaryotes/archaea	Conserved Site
K	IPR023563	Large ribosomal subunit protein uL13, conserved site	Conserved Site
K	IPR005822	Large ribosomal subunit protein uL13	Family
K	IPR036899	Large ribosomal subunit protein uL13 superfamily	Homologous Superfamily
K	IPR005755	Large ribosomal subunit protein uL13, eukaryotic/archaeal	Family
L	IPR019971	Large ribosomal subunit protein uL14, archaeal	Family
L	IPR036853	Large ribosomal subunit protein uL14 superfamily	Homologous Superfamily
L	IPR000218	Large ribosomal subunit protein uL14	Family
L	IPR019972	Large ribosomal subunit protein uL14, conserved site	Conserved Site
O	IPR005485	Large ribosomal subunit protein uL18 eukaryotic/archaeal	Family
P	IPR022947	Large ribosomal subunit protein eL18, archaea	Family
P	IPR021131	Large ribosomal subunit protein uL15/eL18	Domain
P	IPR021132	Large ribosomal subunit protein eL18, conserved site	Conserved Site
P	IPR001196	Large ribosomal subunit protein uL15, conserved site	Conserved Site
P	IPR000039	Large ribosomal subunit protein eL18	Family
P	IPR036227	Large ribosomal subunit protein uL15/eL18 superfamily	Homologous Superfamily
T	IPR012678	Ribosomal protein uL23/eL15/eS24 core domain superfamily	Homologous Superfamily
T	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	Homologous Superfamily
T	IPR019985	Large ribosomal subunit protein uL23	Family
T	IPR001014	Large ribosomal subunit protein uL23, conserved site	Conserved Site
T	IPR013025	Large ribosomal subunit protein uL23-like	Family
V	IPR023438	Ribosomal_eL24	Unknown
V	IPR011017	TRASH domain	Domain
V	IPR000988	Large ribosomal subunit protein eL24-related, N-terminal	Domain
V	IPR023442	Large ribosomal subunit protein eL24, conserved site	Conserved Site
V	IPR038630	Ribosomal protein L24e/L24 superfamily	Homologous Superfamily
X	IPR035808	Large ribosomal subunit protein uL30, eukaryotic/archaeal	Domain
X	IPR036919	Large ribosomal subunit protein uL30, ferredoxin-like fold domain superfamily	Homologous Superfamily
X	IPR039699	Large ribosomal subunit protein uL30	Family
X	IPR016082	Large ribosomal subunit protein uL30-like, ferredoxin-like fold domain	Domain
X	IPR018038	Large ribosomal subunit protein uL30, conserved site	Conserved Site
X	IPR005997	Large ribosomal subunit protein uL30, archaeal	Family
Y	IPR020052	Large ribosomal subunit protein eL31, conserved site	Conserved Site
Y	IPR023621	Large ribosomal subunit protein eL31 domain superfamily	Homologous Superfamily
Y	IPR000054	Large ribosomal subunit protein eL31	Family
Z	IPR001515	Large ribosomal subunit protein eL32	Family
Z	IPR018263	Large ribosomal subunit protein eL32, conserved site	Conserved Site
Z	IPR036351	Large ribosomal subunit protein eL32 superfamily	Homologous Superfamily
Z	IPR023654	Large ribosomal subunit protein eL32, archaeal	Family
Z	IPR010995	DNA repair Rad51/transcription factor NusA, alpha-helical	Homologous Superfamily
Z	IPR003583	Helix-hairpin-helix DNA-binding motif, class 1	Domain
AA [auth 1]	IPR002674	Large ribosomal subunit protein eL43	Family
AA [auth 1]	IPR011332	Zinc-binding ribosomal protein	Homologous Superfamily
AA [auth 1]	IPR011331	Large ribosomal subunit protein eL37/eL43	Homologous Superfamily
AA [auth 1]	IPR050522	Eukaryotic ribosomal protein eL43	Family
DA [auth 4]	IPR053708	Eukaryotic Ribosomal Large Subunit eL42	Homologous Superfamily
DA [auth 4]	IPR011332	Zinc-binding ribosomal protein	Homologous Superfamily
DA [auth 4]	IPR000552	Large ribosomal subunit protein eL42	Family
M	IPR027386	Ribosomal uL15, N-terminal	Homologous Superfamily
M	IPR021131	Large ribosomal subunit protein uL15/eL18	Domain
M	IPR030878	Large ribosomal subunit protein uL15	Family
M	IPR001196	Large ribosomal subunit protein uL15, conserved site	Conserved Site
M	IPR036227	Large ribosomal subunit protein uL15/eL18 superfamily	Homologous Superfamily
N	IPR012678	Ribosomal protein uL23/eL15/eS24 core domain superfamily	Homologous Superfamily
N	IPR020925	Large ribosomal subunit protein eL15, conserved site	Conserved Site
N	IPR024794	Large ribosomal subunit protein eL15 core domain superfamily	Homologous Superfamily
N	IPR020926	Large ribosomal subunit protein eL15, archaeal	Family
N	IPR000439	Large ribosomal subunit protein eL15	Family
Q	IPR015972	Large ribosomal subunit protein eL19, domain 1	Homologous Superfamily
Q	IPR015974	Large ribosomal subunit protein eL19, domain 3	Homologous Superfamily
Q	IPR039547	Large ribosomal subunit protein eL19	Family
Q	IPR033936	Large ribosomal subunit protein eL19, archaeal	Domain
Q	IPR023638	Large ribosomal subunit protein eL19, conserved site	Conserved Site
Q	IPR035970	Large ribosomal subunit protein eL19 superfamily	Homologous Superfamily
Q	IPR000196	Large ribosomal subunit protein eL19 domain	Domain
Q	IPR015973	Large ribosomal subunit protein eL19, domain 2	Homologous Superfamily
R	IPR022856	Large ribosomal subunit protein eL21, archaeal	Family
R	IPR018259	Large ribosomal subunit protein eL21, conserved site	Conserved Site
R	IPR036948	Large ribosomal subunit protein eL21 superfamily	Homologous Superfamily
R	IPR001147	Large ribosomal subunit protein eL21	Family
R	IPR008991	Translation protein SH3-like domain superfamily	Homologous Superfamily
S	IPR018260	Large ribosomal subunit protein uL22, conserved site	Conserved Site
S	IPR036394	Ribosomal protein uL22 superfamily	Homologous Superfamily
S	IPR001063	Large ribosomal subunit protein uL22	Family
S	IPR005721	Large ribosomal subunit protein uL22, eukaryotic/archaeal	Family
U	IPR041988	Large ribosomal subunit protein uL24, KOW domain	Domain
U	IPR014722	Large ribosomal subunit protein uL2, domain 2	Homologous Superfamily
U	IPR005824	KOW	Domain
U	IPR008991	Translation protein SH3-like domain superfamily	Homologous Superfamily
U	IPR005756	Large ribosomal subunit protein uL24, eukaryotic/archaeal	Family
U	IPR005825	Large ribosomal subunit protein uL24, conserved site	Conserved Site
W	IPR050063	Universal ribosomal protein uL29	Family
W	IPR001854	Large ribosomal subunit protein uL29	Family
W	IPR036049	Large ribosomal subunit protein uL29 superfamily	Homologous Superfamily
W	IPR018254	Large ribosomal subunit protein uL29, conserved site	Conserved Site
BA [auth 2]	IPR001569	Large ribosomal subunit protein eL37	Family
BA [auth 2]	IPR018267	Large ribosomal subunit protein eL37, conserved site	Conserved Site
BA [auth 2]	IPR011332	Zinc-binding ribosomal protein	Homologous Superfamily
BA [auth 2]	IPR011331	Large ribosomal subunit protein eL37/eL43	Homologous Superfamily
CA [auth 3]	IPR023626	Large ribosomal subunit protein eL39 domain superfamily	Homologous Superfamily
CA [auth 3]	IPR000077	Large ribosomal subunit protein eL39	Family
CA [auth 3]	IPR020083	Large ribosomal subunit protein eL39, conserved site	Conserved Site
C	IPR022669	Large ribosomal subunit protein uL2, C-terminal	Domain
C	IPR014722	Large ribosomal subunit protein uL2, domain 2	Homologous Superfamily
C	IPR008991	Translation protein SH3-like domain superfamily	Homologous Superfamily
C	IPR023672	Large ribosomal subunit protein uL2, archaeal-type	Family
C	IPR022671	Large ribosomal subunit protein uL2, conserved site	Conserved Site
C	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
C	IPR022666	Large ribosomal subunit protein uL2, RNA-binding domain	Domain
C	IPR014726	Large ribosomal subunit protein uL2, domain 3	Homologous Superfamily
C	IPR002171	Large ribosomal subunit protein uL2	Family
F	IPR020929	Large ribosomal subunit protein uL5, conserved site	Conserved Site
F	IPR022803	Large ribosomal subunit protein uL5 domain superfamily	Homologous Superfamily
F	IPR022804	Large ribosomal subunit protein uL5, archaeal	Family
F	IPR031309	Large ribosomal subunit protein uL5, C-terminal	Domain
F	IPR031310	Large ribosomal subunit protein uL5, N-terminal	Domain
F	IPR002132	Large ribosomal subunit protein uL5	Family
H	IPR050257	Large ribosomal subunit protein eL8/uL1-like	Family
H	IPR004038	Ribosomal protein eL8/eL30/eS12/Gadd45	Domain
H	IPR022481	Large ribosomal subunit protein eL8, archaea	Family
H	IPR004037	Large ribosomal subunit protein eL8-like, conserved site	Conserved Site
H	IPR029064	Ribosomal protein eL30-like superfamily	Homologous Superfamily
H	IPR018492	Ribosomal protein eL8/Nhp2 family	Family