Annotations: 1AX3

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1ax3a_	All beta proteins	Barrel-sandwich hybrid	Duplicated hybrid motif	Glucose permease-like	Glucose permease IIa domain, IIa-glc	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PTS_EIIA_1	e1ax3A1	A: a+b complex topology	X: alpha/beta-Hammerhead/Barrel-sandwich hybrid	H: alpha/beta-Hammerhead/Barrel-sandwich hybrid	T: Duplicated hybrid motif	F: PTS_EIIA_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.70.70.10	Mainly Beta	Distorted Sandwich	Glucose Permease (Domain IIA)	Glucose Permease (Domain IIA)	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00358	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 (PTS_EIIA_1)	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1		Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	GLUCOSE PERMEASE IIA DOMAIN	kinase activity transferase activity catalytic activity transferase activity, transferring phosphorus-containing groups active transmembrane transporter activity protein-N(PI)-phosphohistidine-sugar phosphotransferase activity transporter activity carbohydrate transmembrane transporter activity transmembrane transporter activity phosphotransferase activity, alcohol group as acceptor monosaccharide transmembrane transporter activity sugar transmembrane transporter activity D-glucose transmembrane transporter activity hexose transmembrane transporter activity kinase activity transferase activity catalytic activity transferase activity, transferring phosphorus-containing groups active transmembrane transporter activity protein-N(PI)-phosphohistidine-sugar phosphotransferase activity transporter activity carbohydrate transmembrane transporter activity transmembrane transporter activity phosphotransferase activity, alcohol group as acceptor monosaccharide transmembrane transporter activity sugar transmembrane transporter activity D-glucose transmembrane transporter activity hexose transmembrane transporter activity protein-phosphocysteine-sugar phosphotransferase activity	import into cell phosphoenolpyruvate-dependent sugar phosphotransferase system transport import across plasma membrane carbohydrate import across plasma membrane carbohydrate transport establishment of localization transmembrane transport localization cellular process carbohydrate transmembrane transport hexose transmembrane transport D-glucose transmembrane transport monosaccharide transmembrane transport	cell periphery cellular anatomical structure plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR018113	Phosphotransferase system EIIB, cysteine phosphorylation site	Conserved Site
A	IPR013013	Phosphotransferase system, EIIC component, type 1	Domain
A	IPR001127	Phosphotransferase system, sugar-specific permease EIIA type 1	Domain
A	IPR011299	PTS system glucose-specific IIBC component	Domain
A	IPR011055	Duplicated hybrid motif	Homologous Superfamily
A	IPR036878	Glucose permease domain IIB	Homologous Superfamily
A	IPR050429	Phosphotransferase System Glucose-Specific EIICBA	Family
A	IPR001996	Phosphotransferase system, IIB component, type 1	Domain
A	IPR004719	Phosphotransferase system, maltose/glucose-specific subfamily IIC component	Domain
A	IPR003352	Phosphotransferase system, EIIC	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.