2FGU

X-ray crystal structure of HIV-1 Protease T80S variant in complex with the inhibitor saquinavir used to explore the role of invariant Thr80 in HIV-1 protease structure, function, and viral infectivity.

Changes made to a PDB entry after its initial release are considered to be either “major” or “minor”. The latest minor version of each major version is available as a file download. More information about the PDB versioning is available.

Version Number	Version Date	Version Type/Reason	Version Change	Revised CIF Category
1.0	2006-11-07	Initial release
1.1	2008-05-01		Version format compliance
1.2	2011-07-13		Non-polymer description, Version format compliance
1.3	2017-10-18		Refinement description	software
1.4	2021-10-20		Database references, Derived calculations	database_2, struct_conn, struct_ref_seq_dif, struct_site
1.5	2023-08-30		Data collection, Refinement description	chem_comp_atom, chem_comp_bond, pdbx_initial_refinement_model	Download

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.