Download MendeleyCrystal structure of C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with (1H-pyrazol-3-yl)methanol
Audebert, S., Gelin, M., Guichou, J.-F.To be published.
9HSV | pdb_00009hsv
Crystal structure of C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with (1H-pyrazol-3-yl)methanol
- PDB DOI: https://doi.org/10.2210/pdb9HSV/pdb
- Classification: TRANSFERASE
- Organism(s): Plasmodium falciparum
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2024-12-19 Released: 2025-02-05
- Funding Organization(s): Agence Nationale de la Recherche (ANR)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.68 Å
- R-Value Free: 0.221 (Depositor), 0.221 (DCC)
- R-Value Work: 0.198 (Depositor), 0.197 (DCC)
- R-Value Observed: 0.199 (Depositor)
Starting Model: experimental
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This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| choline-phosphate cytidylyltransferase | 179 | Plasmodium falciparum | Mutation(s): 0 Gene Names: PF3D7_1316600 EC: 2.7.7.15 |  | |
UniProt | |||||
Find proteins for P49587 (Plasmodium falciparum (isolate K1 / Thailand)) Explore P49587 Go to UniProtKB: P49587 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P49587 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| IRU (Subject of Investigation/LOI) Query on IRU | B [auth A], C [auth A], D [auth A] | 1~{H}-pyrazol-5-ylmethanol C4 H6 N2 O UIEABCXJWANXFS-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.68 Å
- R-Value Free: 0.221 (Depositor), 0.221 (DCC)
- R-Value Work: 0.198 (Depositor), 0.197 (DCC)
- R-Value Observed: 0.199 (Depositor)
Space Group: I 2 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 50.15 | α = 90 |
| b = 71.112 | β = 90 |
| c = 118.916 | γ = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-02-05 Deposition Author(s): Audebert, S., Gelin, M., Guichou, J.-F.
| Funding Organization | Location | Grant Number |
|---|---|---|
| Agence Nationale de la Recherche (ANR) | France | ANR-20-CE44-0012 |
Revision History (Full details and data files)
- Version 1.0: 2025-02-05
Type: Initial release
