Crystal Structure of Hsp90-alpha N-Domain in complex with resorcinol derivative
Amaral, M.To be published.
Experimental Data Snapshot
Entity ID: 1 | |||||
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Molecule | Chains | Sequence Length | Organism | Details | Image |
Heat shock protein HSP 90-alpha | 229 | Homo sapiens | Mutation(s): 0  Gene Names: HSP90AA1, HSP90A, HSPC1, HSPCA EC: 3.6.4.10 | ||
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P07900 (Homo sapiens) Explore P07900  Go to UniProtKB:  P07900 | |||||
PHAROS:  P07900 GTEx:  ENSG00000080824  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P07900 | ||||
Sequence AnnotationsExpand | |||||
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Ligands 1 Unique | |||||
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ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
2EQ Query on 2EQ | B [auth A] | 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]isoxazole-3-carboxamide C23 H24 Cl N3 O5 APGOABVITLQCKW-UHFFFAOYSA-N |
Length ( Å ) | Angle ( ˚ ) |
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a = 66.43 | α = 90 |
b = 89.088 | β = 90 |
c = 99.944 | γ = 90 |
Software Name | Purpose |
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BUSTER | refinement |
XDS | data reduction |
XDS | data scaling |
PHATHR | phasing |