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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Enzyme Classification Number = 2.4.2

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Search Summary

This query matches 2,027 Structures.

Refinements

Structure Determination Methodology

experimental (2,027)

Scientific Name of Source Organism

	Homo sapiens (835)
	Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821 (109)
	Escherichia coli (63)
	Zymomonas mobilis (63)
	Schistosoma mansoni (60)
	Vibrio cholerae (43)
	Mycobacterium tuberculosis (39)
	Mycobacterium tuberculosis H37Rv (31)
	Escherichia coli K-12 (30)
	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 (30)

More...

Taxonomy

	Eukaryota (1,127)
	Bacteria (868)
	Archaea (53)
	other sequences (19)
	Duplodnaviria (10)
	unclassified sequences (3)
	Varidnaviria (1)

Experimental Method

	X-RAY DIFFRACTION (1,974)
	ELECTRON MICROSCOPY (37)
	SOLUTION NMR (16)

Polymer Entity Type

	Protein (2,027)
	DNA (31)
	RNA (5)

Refinement Resolution (Å)

	0.5 - 1.0 (7)
	1.0 - 1.5 (216)
	1.5 - 2.0 (739)
	2.0 - 2.5 (654)
	2.5 - 3.0 (313)
	3.0 - 3.5 (62)
	3.5 - 4.0 (14)
	4.0 - 4.5 (3)
	> 4.5 (3)

Release Date

	1990 - 1994 (8)
	1995 - 1999 (82)
	2000 - 2004 (203)
	2005 - 2009 (308)
	2010 - 2014 (463)
	2015 - 2019 (546)
	2020 - 2024 (397)
	2025 - 2029 (20)

Enzyme Classification Name

	Transferases (2,027)
	Hydrolases (91)
	Lyases (75)
	Ligases (14)
	Oxidoreductases (5)
	Isomerases (2)

Membrane Protein Annotation

	PDBTM (17)
	MemProtMD (14)
	OPM (13)
	mpstruc (7)

Symmetry Type

	Asymmetric (720)
	Cyclic (988)
	Dihedral (403)
	Helical (3)

SCOP Classification

	Alpha and beta proteins (a/b) (969)
	Alpha and beta proteins (a+b) (329)
	Artifacts (154)
	All alpha proteins (112)
	All beta proteins (42)
	Membrane and cell surface proteins and peptides (16)
	Small proteins (11)

AllSelected

1 to 25 of 2,027 Structures

Page 1 of 82

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1A26 \| pdb_00001a26	Download File View File

THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH CARBA-NAD

Ruf, A., Schulz, G.E.

(1998) J Mol Biology 278: 57-65

Released	1998-05-27
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Gallus gallus
Macromolecule	POLY (ADP-RIBOSE) POLYMERASE (protein)
Unique Ligands	CNA

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1A3C \| pdb_00001a3c	Download File View File

PYRR, THE BACILLUS SUBTILIS PYRIMIDINE BIOSYNTHETIC OPERON REPRESSOR, DIMERIC FORM

Tomchick, D.R., Turner, R.J., Switzer, R.W., Smith, J.L.

(1998) Structure 6: 337-350

Released	1998-08-05
Method	X-RAY DIFFRACTION 1.6 Å
Organisms	Bacillus subtilis
Macromolecule	PYRIMIDINE OPERON REGULATORY PROTEIN PYRR (protein)
Unique Ligands	SM, SO4

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1A4X \| pdb_00001a4x	Download File View File

PYRR, THE BACILLUS SUBTILIS PYRIMIDINE BIOSYNTHETIC OPERON REPRESSOR, HEXAMERIC FORM

Tomchick, D.R., Turner, R.J., Switzer, R.W., Smith, J.L.

(1998) Structure 6: 337-350

Released	1998-08-05
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Bacillus subtilis
Macromolecule	PYRIMIDINE OPERON REGULATORY PROTEIN PYRR (protein)
Unique Ligands	SO4

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1A69 \| pdb_00001a69	Download File View File

PURINE NUCLEOSIDE PHOSPHORYLASE IN COMPLEX WITH FORMYCIN B AND SULPHATE (PHOSPHATE)

Koellner, G., Luic, M., Shugar, D., Saenger, W., Bzowska, A.

(1998) J Mol Biology 280: 153-166

Released	1998-10-14
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Escherichia coli
Macromolecule	PURINE NUCLEOSIDE PHOSPHORYLASE (protein)
Unique Ligands	FMB, SO4

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1A95 \| pdb_00001a95	Download File View File

XPRTASE FROM E. COLI COMPLEXED WITH MG:CPRPP AND GUANINE

Vos, S., Parry, R.J., Burns, M.R., De Jersey, J., Martin, J.L.

(1998) J Mol Biology 282: 875-889

Released	1998-11-11
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli
Macromolecule	XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE (protein)
Unique Ligands	BO3, GUN, MG, PCP

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1A96 \| pdb_00001a96	Download File View File

XPRTASE FROM E. COLI WITH BOUND CPRPP AND XANTHINE

Vos, S., Parry, R.J., Burns, M.R., De Jersey, J., Martin, J.L.

(1998) J Mol Biology 282: 875-889

Released	1998-11-11
Method	X-RAY DIFFRACTION 2 Å
Organisms	Escherichia coli
Macromolecule	XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE (protein)
Unique Ligands	BO3, MG, PCP, XAN

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1A97 \| pdb_00001a97	Download File View File

XPRTASE FROM E. COLI COMPLEXED WITH GMP

Vos, S., Parry, R.J., Burns, M.R., De Jersey, J., Martin, J.L.

(1998) J Mol Biology 282: 875-889

Released	1998-11-11
Method	X-RAY DIFFRACTION 2.6 Å
Organisms	Escherichia coli
Macromolecule	XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE (protein)
Unique Ligands	5GP, BO3

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1A98 \| pdb_00001a98	Download File View File

XPRTASE FROM E. COLI COMPLEXED WITH GMP

Vos, S., Parry, R.J., Burns, M.R., De Jersey, J., Martin, J.L.

(1998) J Mol Biology 282: 875-889

Released	1998-06-17
Method	X-RAY DIFFRACTION 2.25 Å
Organisms	Escherichia coli
Macromolecule	XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE (protein)

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1A9O \| pdb_00001a9o	Download File View File

BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH PHOSPHATE

Mao, C., Cook, W.J., Zhou, M., Fedorov, A.A., Almo, S.C., Ealick, S.E.

(1998) Biochemistry 37: 7135-7146

Released	1998-07-15
Method	X-RAY DIFFRACTION 2 Å
Organisms	Bos taurus
Macromolecule	PURINE NUCLEOSIDE PHOSPHORYLASE (protein)
Unique Ligands	PO4

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1A9P \| pdb_00001a9p	Download File View File

BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-DEAZAINOSINE AND PHOSPHATE

Mao, C., Cook, W.J., Zhou, M., Fedorov, A.A., Almo, S.C., Ealick, S.E.

(1998) Biochemistry 37: 7135-7146

Released	1998-07-15
Method	X-RAY DIFFRACTION 2.4 Å
Organisms	Bos taurus
Macromolecule	PURINE NUCLEOSIDE PHOSPHORYLASE (protein)
Unique Ligands	9DI, PO4

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1A9Q \| pdb_00001a9q	Download File View File

BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH INOSINE

Mao, C., Cook, W.J., Zhou, M., Fedorov, A.A., Almo, S.C., Ealick, S.E.

(1998) Biochemistry 37: 7135-7146

Released	1998-07-15
Method	X-RAY DIFFRACTION 2 Å
Organisms	Bos taurus
Macromolecule	PURINE NUCLEOSIDE PHOSPHORYLASE (protein)
Unique Ligands	HPA, SO4

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1A9R \| pdb_00001a9r	Download File View File

BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH HYPOXANTHINE AND SULFATE

Mao, C., Cook, W.J., Zhou, M., Fedorov, A.A., Almo, S.C., Ealick, S.E.

(1998) Biochemistry 37: 7135-7146

Released	1998-07-15
Method	X-RAY DIFFRACTION 2 Å
Organisms	Bos taurus
Macromolecule	PURINE NUCLEOSIDE PHOSPHORYLASE (protein)
Unique Ligands	HPA, SO4

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1A9S \| pdb_00001a9s	Download File View File

BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH INOSINE AND SULFATE

Mao, C., Cook, W.J., Zhou, M., Fedorov, A.A., Almo, S.C., Ealick, S.E.

(1998) Biochemistry 37: 7135-7146

Released	1998-07-15
Method	X-RAY DIFFRACTION 2 Å
Organisms	Bos taurus
Macromolecule	PURINE NUCLEOSIDE PHOSPHORYLASE (protein)
Unique Ligands	NOS, SO4

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1A9T \| pdb_00001a9t	Download File View File

BOVINE PURINE NUCLEOSIDE PHOSPHORYLASE COMPLEXED WITH 9-DEAZAINOSINE AND PHOSPHATE

Mao, C., Cook, W.J., Zhou, M., Fedorov, A.A., Almo, S.C., Ealick, S.E.

(1998) Biochemistry 37: 7135-7146

Released	1998-06-17
Method	X-RAY DIFFRACTION 2 Å
Organisms	Bos taurus
Macromolecule	PURINE NUCLEOSIDE PHOSPHORYLASE (protein)
Unique Ligands	HPA, R1P

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1AER \| pdb_00001aer	Download File View File

DOMAIN III OF PSEUDOMONAS AERUGINOSA EXOTOXIN COMPLEXED WITH BETA-TAD

Li, M., Dyda, F., Benhar, I., Pastan, I., Davies, D.R.

(1996) Proc Natl Acad Sci U S A 93: 6902-6906

Released	1996-06-10
Method	X-RAY DIFFRACTION 2.3 Å
Organisms	Pseudomonas aeruginosa
Macromolecule	EXOTOXIN A (protein)
Unique Ligands	AMP, TAD, TIA

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1AO0 \| pdb_00001ao0	Download File View File

GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE (PRPP) AMIDOTRANSFERASE FROM B. SUBTILIS COMPLEXED WITH ADP AND GMP

Tomchick, D.R., Smith, J.L.

(1997) Biochemistry 36: 10718-10726

Released	1997-11-12
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Bacillus subtilis
Macromolecule	GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE (protein)
Unique Ligands	5GP, ADP, MG, SF4

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1AZY \| pdb_00001azy	Download File View File

STRUCTURAL AND THEORETICAL STUDIES SUGGEST DOMAIN MOVEMENT PRODUCES AN ACTIVE CONFORMATION OF THYMIDINE PHOSPHORYLASE

Pugmire, M.J., Cook, W.J., Jasanoff, A., Walter, M.R., Ealick, S.E.

(1998) J Mol Biology 281: 285-299

Released	1999-01-13
Method	X-RAY DIFFRACTION 3 Å
Organisms	Escherichia coli K-12
Macromolecule	THYMIDINE PHOSPHORYLASE (protein)

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1B8N \| pdb_00001b8n	Download File View File

PURINE NUCLEOSIDE PHOSPHORYLASE

Fedorov, A.A., Kicska, G.A., Fedorov, E.V., Strokopytov, B.V., Tyler, P.C., Furneaux, R.H., Schramm, V.L., Almo, S.C.

(2002) Biochemistry 41: 14489-14498

Released	1999-02-08
Method	X-RAY DIFFRACTION 2 Å
Organisms	Bos taurus
Macromolecule	PURINE NUCLEOSIDE PHOSPHORYLASE (protein)
Unique Ligands	IMG, MG, PO4

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1B8O \| pdb_00001b8o	Download File View File

PURINE NUCLEOSIDE PHOSPHORYLASE

Fedorov, A.A., Kicska, G.A., Fedorov, E.V., Shi, W., Tyler, P.C., Furneaux, R.H., Schramm, V.L., Almo, S.C.

(2001) Biochemistry 40: 853-860

Released	1999-02-08
Method	X-RAY DIFFRACTION 1.5 Å
Organisms	Bos taurus
Macromolecule	PURINE NUCLEOSIDE PHOSPHORYLASE (protein)
Unique Ligands	IMH, MG, PO4

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1BCP \| pdb_00001bcp	Download File View File

BINARY COMPLEX OF PERTUSSIS TOXIN AND ATP

Hazes, B., Read, R.J.

(1996) J Mol Biology 258: 661-671

Released	1997-06-05
Method	X-RAY DIFFRACTION 2.7 Å
Organisms	Bordetella pertussis
Macromolecule	PERTUSSIS TOXIN (protein)
Unique Ligands	ATP

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1BD3 \| pdb_00001bd3	Download File View File

STRUCTURE OF THE APO URACIL PHOSPHORIBOSYLTRANSFERASE, 2 MUTANT C128V

Schumacher, M.A., Carter, D., Scott, D., Roos, D., Ullman, B., Brennan, R.G.

(1998) EMBO J 17: 3219-3232

Released	1999-05-18
Method	X-RAY DIFFRACTION 1.93 Å
Organisms	Toxoplasma gondii
Macromolecule	URACIL PHOSPHORIBOSYLTRANSFERASE (protein)
Unique Ligands	PO4

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1BD4 \| pdb_00001bd4	Download File View File

UPRT-URACIL COMPLEX

Schumacher, M.A., Carter, D., Scott, D., Roos, D., Ullman, B., Brennan, R.G.

(1998) EMBO J 17: 3219-3232

Released	1999-05-18
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Toxoplasma gondii
Macromolecule	URACIL PHOSPHORIBOSYLTRANSFERASE (protein)
Unique Ligands	PO4, URA

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1BRW \| pdb_00001brw	Download File View File

THE CRYSTAL STRUCTURE OF PYRIMIDINE NUCLEOSIDE PHOSPHORYLASE IN A CLOSED CONFORMATION

Pugmire, M.J., Ealick, S.E.

(1998) Structure 6: 1467-1479

Released	1999-01-13
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Geobacillus stearothermophilus
Macromolecule	PROTEIN (PYRIMIDINE NUCLEOSIDE PHOSPHORYLASE) (protein)
Unique Ligands	CA, MES, PO4, URA

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1BZY \| pdb_00001bzy	Download File View File

HUMAN HGPRTASE WITH TRANSITION STATE INHIBITOR

Shi, W., Li, C., Tyler, P.C., Furneaux, R.H., Grubmeyer, C., Schramm, V.L., Almo, S.C.

(1999) Nat Struct Biol 6: 588-593

Released	1999-06-22
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens
Macromolecule	HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE (protein)
Unique Ligands	IMU, MG, POP