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233,605 Structures from the PDB

1,068,577 Computed Structure Models (CSM)

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QUERY: Source Organism Taxonomy Name (Full Lineage) = "Tolypocladium inflatum"

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Search Summary

This query matches 50 Structures.

Refinements

Structure Determination Methodology

experimental (50)

Scientific Name of Source Organism

	Tolypocladium inflatum (50)
	Homo sapiens (31)
	Plasmodium falciparum (2)
	Bos taurus (1)
	Brassica napus (1)
	Brugia malayi (1)
	Chlorocebus aethiops (1)
	Citrus sinensis (1)
	Cryptosporidium parvum Iowa II (1)
	Leishmania donovani (1)

More...

Taxonomy

	Eukaryota (50)
	other sequences (1)

Experimental Method

	X-RAY DIFFRACTION (44)
	SOLUTION NMR (5)
	ELECTRON MICROSCOPY (1)

Polymer Entity Type

Protein (50)

Refinement Resolution (Å)

	0.5 - 1.0 (2)
	1.0 - 1.5 (3)
	1.5 - 2.0 (18)
	2.0 - 2.5 (15)
	2.5 - 3.0 (4)
	3.0 - 3.5 (2)
	3.5 - 4.0 (1)

Release Date

	1990 - 1994 (4)
	1995 - 1999 (20)
	2000 - 2004 (5)
	2005 - 2009 (7)
	2010 - 2014 (9)
	2015 - 2019 (2)
	2020 - 2024 (3)

Enzyme Classification Name

	Isomerases (44)
	Hydrolases (2)
	Oxidoreductases (1)
	Translocases (1)

Membrane Protein Annotation

mpstruc (1)

Symmetry Type

	Asymmetric (46)
	Cyclic (2)
	Dihedral (4)

SCOP Classification

	All beta proteins (34)
	All alpha proteins (3)
	Alpha and beta proteins (a/b) (1)
	Alpha and beta proteins (a+b) (2)
	Artifacts (1)

AllSelected

1 to 25 of 50 Structures

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1BCK \| pdb_00001bck	Download File View File

HUMAN CYCLOPHILIN A COMPLEXED WITH 2-THR CYCLOSPORIN

Mikol, V., Kallen, J., Taylor, P., Walkinshaw, M.D.

(1998) J Mol Biology 283: 435

Released	1998-09-16
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN C (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)

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1C5F \| pdb_00001c5f	Download File View File

CRYSTAL STRUCTURE OF THE CYCLOPHILIN-LIKE DOMAIN FROM BRUGIA MALAYI COMPLEXED WITH CYCLOSPORIN A

Ellis, P.J., Carlow, C.K.S., Ma, D., Kuhn, P.

(2000) Biochemistry 39: 592

Released	1999-12-03
Method	X-RAY DIFFRACTION 2.47 Å
Organisms	Brugia malayi Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE 1 (protein)

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1CSA \| pdb_00001csa	Download File View File

THE MUTANT E.COLI F112W CYCLOPHILIN BINDS CYCLOSPORIN A IN NEARLY IDENTICAL CONFORMATION AS HUMAN CYCLOPHILIN

Fejzo, J., Walsh, C.T., Wagner, G.

(1994) Biochemistry 33: 5711

Released	1994-04-30
Method	SOLUTION NMR
Organisms	Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein)

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1CWA \| pdb_00001cwa	Download File View File

X-RAY STRUCTURE OF A MONOMERIC CYCLOPHILIN A-CYCLOSPORIN A CRYSTAL COMPLEX AT 2.1 ANGSTROMS RESOLUTION

Mikol, V., Kallen, J., Walkinshaw, M.D.

(1993) J Mol Biology 234: 1119

Released	1996-01-29
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)

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1CWB \| pdb_00001cwb	Download File View File

THE X-RAY STRUCTURE OF (MEBM2T)1-CYCLOSPORIN COMPLEXED WITH CYCLOPHILIN A PROVIDES AN EXPLANATION FOR ITS ANOMALOUSLY HIGH IMMUNOSUPPRESSIVE ACTIVITY

Mikol, V., Kallen, J., Walkinshaw, M.D.

(1994) Protein Eng 7: 597

Released	1996-01-29
Method	X-RAY DIFFRACTION 2.2 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)

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1CWC \| pdb_00001cwc	Download File View File

IMPROVED BINDING AFFINITY FOR CYCLOPHILIN A BY A CYCLOSPORIN DERIVATIVE SINGLY MODIFIED AT ITS EFFECTOR DOMAIN

Mikol, V.

(1994) J Med Chem 37: 3674

Released	1996-01-29
Method	X-RAY DIFFRACTION 1.86 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)

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1CWF \| pdb_00001cwf	Download File View File

HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL CYCLOSPORIN

Mikol, V., Kallen, J., Taylor, P., Walkinshaw, M.D.

(1998) J Mol Biology 283: 435

Released	1998-07-15
Method	X-RAY DIFFRACTION 1.86 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN D (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)

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1CWH \| pdb_00001cwh	Download File View File

HUMAN CYCLOPHILIN A COMPLEXED WITH 3-D-SER CYCLOSPORIN

Mikol, V., Kallen, J., Taylor, P., Walkinshaw, M.D.

(1998) J Mol Biology 283: 435

Released	1998-07-15
Method	X-RAY DIFFRACTION 1.86 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)

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1CWI \| pdb_00001cwi	Download File View File

HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL 3-(N-METHYL)-D-ALANINE CYCLOSPORIN

Mikol, V., Kallen, J., Taylor, P., Walkinshaw, M.D.

(1998) J Mol Biology 283: 435

Released	1998-08-12
Method	X-RAY DIFFRACTION 1.9 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN D (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)

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1CWJ \| pdb_00001cwj	Download File View File

HUMAN CYCLOPHILIN A COMPLEXED WITH 2-VAL 3-S-METHYL-SARCOSINE CYCLOSPORIN

Mikol, V., Kallen, J., Taylor, P., Walkinshaw, M.D.

(1998) J Mol Biology 283: 435

Released	1998-08-26
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN D (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)

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1CWK \| pdb_00001cwk	Download File View File

HUMAN CYCLOPHILIN A COMPLEXED WITH 1-(6,7-DIHYDRO)MEBMT 2-VAL 3-D-(2-S-METHYL)SARCOSINE CYCLOSPORIN

Mikol, V., Kallen, J., Taylor, P., Walkinshaw, M.D.

(1998) J Mol Biology 283: 435

Released	1998-07-15
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN D (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)

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1CWL \| pdb_00001cwl	Download File View File

HUMAN CYCLOPHILIN A COMPLEXED WITH 4 4-HYDROXY-MELEU CYCLOSPORIN

Mikol, V., Kallen, J., Taylor, P., Walkinshaw, M.D.

(1998) J Mol Biology 283: 435

Released	1998-07-15
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)

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1CWM \| pdb_00001cwm	Download File View File

HUMAN CYCLOPHILIN A COMPLEXED WITH 4 MEILE CYCLOSPORIN

Mikol, V., Kallen, J., Taylor, P., Walkinshaw, M.D.

(1998) J Mol Biology 283: 435

Released	1998-07-15
Method	X-RAY DIFFRACTION 2 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)

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1CWO \| pdb_00001cwo	Download File View File

HUMAN CYCLOPHILIN A COMPLEXED WITH THR2, LEU5, D-HIV8, LEU10 CYCLOSPORIN

Mikol, V., Kallen, J., Taylor, P., Walkinshaw, M.D.

(1998) J Mol Biology 283: 451

Released	1998-08-12
Method	X-RAY DIFFRACTION 1.86 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN C (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)

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1CYA \| pdb_00001cya	Download File View File

NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING

Fesik, S.W.

(1991) Biochemistry 30: 6574

Released	1994-01-31
Method	SOLUTION NMR
Organisms	Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein)

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1CYB \| pdb_00001cyb	Download File View File

NMR STUDIES OF (U-13C)CYCLOSPORIN A BOUND TO CYCLOPHILIN: BOUND CONFORMATION AND PORTIONS OF CYCLOSPORIN INVOLVED IN BINDING

Fesik, S.W.

(1991) Biochemistry 30: 6574

Released	1994-01-31
Method	SOLUTION NMR
Organisms	Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein)

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1CYN \| pdb_00001cyn	Download File View File

CYCLOPHILIN B COMPLEXED WITH [D-(CHOLINYLESTER)SER8]-CYCLOSPORIN

Mikol, V., Kallen, J., Walkinshaw, M.D.

(1994) Proc Natl Acad Sci U S A 91: 5183

Released	1996-01-29
Method	X-RAY DIFFRACTION 1.85 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B (protein)

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1EFR \| pdb_00001efr	Download File View File

BOVINE MITOCHONDRIAL F1-ATPASE COMPLEXED WITH THE PEPTIDE ANTIBIOTIC EFRAPEPTIN

Abrahams, J.P., Buchanan, S.K., Van Raaij, M.J., Fearnley, I.M., Leslie, A.G.W., Walker, J.E.

(1996) Proc Natl Acad Sci U S A 93: 9420

Released	1997-02-12
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Bos taurus Tolypocladium inflatum
Macromolecule	BOVINE MITOCHONDRIAL F1-ATPASE SUBUNIT ALPHA (protein) BOVINE MITOCHONDRIAL F1-ATPASE SUBUNIT BETA (protein) BOVINE MITOCHONDRIAL F1-ATPASE SUBUNIT GAMMA (protein) EFRAPEPTIN C (protein)
Unique Ligands	ADP, ANP, MG

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1IKF \| pdb_00001ikf	Download File View File

A CONFORMATION OF CYCLOSPORIN A IN AQUEOUS ENVIRONMENT REVEALED BY THE X-RAY STRUCTURE OF A CYCLOSPORIN-FAB COMPLEX

Vix, O., Altschuh, D., Rees, B., Thierry, J.-C.

(1992) Science 256: 92

Released	1995-03-31
Method	X-RAY DIFFRACTION 2.5 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein) IGG1-KAPPA R45-45-11 FAB (HEAVY CHAIN) (protein) IGG1-KAPPA R45-45-11 FAB (LIGHT CHAIN) (protein)

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1M63 \| pdb_00001m63	Download File View File

Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes

Huai, Q., Kim, H.-Y., Liu, Y., Zhao, Y., Mondragon, A., Liu, J.O., Ke, H.

(2002) Proc Natl Acad Sci U S A 99: 12037

Released	2002-09-25
Method	X-RAY DIFFRACTION 2.8 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CALCINEURIN B SUBUNIT ISOFORM 1 (protein) CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein) SERINE/THREONINE PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT, ALPHA ISOFORM (protein)
Unique Ligands	CA, FE, ZN

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1MF8 \| pdb_00001mf8	Download File View File

Crystal Structure of human calcineurin complexed with cyclosporin A and human cyclophilin

Jin, L., Harrison, S.C.

(2002) Proc Natl Acad Sci U S A 99: 13522

Released	2002-10-16
Method	X-RAY DIFFRACTION 3.1 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CALCINEURIN B SUBUNIT ISOFORM 1 (protein) CALMODULIN-DEPENDENT CALCINEURIN A SUBUNIT, ALPHA ISOFORM (protein) CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)
Unique Ligands	CA, PO4

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1MIK \| pdb_00001mik	Download File View File

THE ROLE OF WATER MOLECULES IN THE STRUCTURE-BASED DESIGN OF (5-HYDROXYNORVALINE)-2-CYCLOSPORIN: SYNTHESIS, BIOLOGICAL ACTIVITY, AND CRYSTALLOGRAPHIC ANALYSIS WITH CYCLOPHILIN A

Mikol, V.

(1995) J Med Chem 38: 3361

Released	1996-03-08
Method	X-RAY DIFFRACTION 1.76 Å
Organisms	Homo sapiens Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A (protein)

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1QNG \| pdb_00001qng	Download File View File

Plasmodium falciparum Cyclophilin complexed with Cyclosporin A

Peterson, M.R., Hall, D.R., Hunter, W.N.

(2000) J Mol Biology 298: 123

Released	2000-10-13
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Plasmodium falciparum Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (protein)

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1QNH \| pdb_00001qnh	Download File View File

Plasmodium falciparum Cyclophilin (double mutant) complexed with Cyclosporin A

Peterson, M.R., Hall, D.R., Hunter, W.N.

(2000) J Mol Biology 298: 123

Released	2000-10-13
Method	X-RAY DIFFRACTION 2.1 Å
Organisms	Plasmodium falciparum Tolypocladium inflatum
Macromolecule	CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (protein)

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1XQ7 \| pdb_00001xq7	Download File View File

Cyclophilin from Trypanosoma cruzi bound to cyclosporin A

Caruthers, J.M., Hol, W.G.J., Structural Genomics of Pathogenic Protozoa Consortium (SGPP)

To be published

Released	2004-12-21
Method	X-RAY DIFFRACTION 2.07 Å
Organisms	Tolypocladium inflatum Trypanosoma cruzi
Macromolecule	CYCLOSPORIN A (protein) PEPTIDYL-PROLYL CIS-TRANS ISOMERASE (protein)

1 to 25 of 50 Structures

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

1BCK | pdb_00001bck

1C5F | pdb_00001c5f

1CSA | pdb_00001csa

1CWA | pdb_00001cwa

1CWB | pdb_00001cwb

1CWC | pdb_00001cwc

1CWF | pdb_00001cwf

1CWH | pdb_00001cwh

1CWI | pdb_00001cwi

1CWJ | pdb_00001cwj

1CWK | pdb_00001cwk

1CWL | pdb_00001cwl

1CWM | pdb_00001cwm

1CWO | pdb_00001cwo

1CYA | pdb_00001cya

1CYB | pdb_00001cyb

1CYN | pdb_00001cyn

1EFR | pdb_00001efr

1IKF | pdb_00001ikf

1M63 | pdb_00001m63

1MF8 | pdb_00001mf8

1MIK | pdb_00001mik

1QNG | pdb_00001qng

1QNH | pdb_00001qnh

1XQ7 | pdb_00001xq7