RCSB PDB: Search

5R7Y \| pdb_00005r7y	Download File View File

PanDDA analysis group deposition -- Crystal Structure of COVID-19 main protease in complex with Z45617795

Fearon, D., Powell, A.J., Douangamath, A., Owen, C.D., Wild, C., Krojer, T., Lukacik, P., Strain-Damerell, C.M., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-11
Method	X-RAY DIFFRACTION 1.65 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	CL, DMS, JFM

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5R7Z \| pdb_00005r7z	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z1220452176

Fearon, D., Powell, A.J., Douangamath, A., Owen, C.D., Wild, C., Krojer, T., Lukacik, P., Strain-Damerell, C.M., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-11
Method	X-RAY DIFFRACTION 1.59 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, HWH

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5R80 \| pdb_00005r80	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z18197050

Fearon, D., Powell, A.J., Douangamath, A., Owen, C.D., Wild, C., Krojer, T., Lukacik, P., Strain-Damerell, C.M., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-11
Method	X-RAY DIFFRACTION 1.93 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, RZG

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5R81 \| pdb_00005r81	Download File View File

PanDDA analysis group deposition -- Crystal Structure of COVID-19 main protease in complex with Z1367324110

Fearon, D., Powell, A.J., Douangamath, A., Owen, C.D., Wild, C., Krojer, T., Lukacik, P., Strain-Damerell, C.M., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-11
Method	X-RAY DIFFRACTION 1.95 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, RZJ

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5R82 \| pdb_00005r82	Download File View File

PanDDA analysis group deposition -- Crystal Structure of COVID-19 main protease in complex with Z219104216

Fearon, D., Powell, A.J., Douangamath, A., Owen, C.D., Wild, C., Krojer, T., Lukacik, P., Strain-Damerell, C.M., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-11
Method	X-RAY DIFFRACTION 1.31 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, RZS

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5R83 \| pdb_00005r83	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z44592329

Fearon, D., Powell, A.J., Douangamath, A., Owen, C.D., Wild, C., Krojer, T., Lukacik, P., Strain-Damerell, C.M., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-11
Method	X-RAY DIFFRACTION 1.58 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, K0G

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5R84 \| pdb_00005r84	Download File View File

PanDDA analysis group deposition -- Crystal Structure of COVID-19 main protease in complex with Z31792168

Fearon, D., Powell, A.J., Douangamath, A., Owen, C.D., Wild, C., Krojer, T., Lukacik, P., Strain-Damerell, C.M., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-11
Method	X-RAY DIFFRACTION 1.83 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, GWS

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5R8T \| pdb_00005r8t	Download File View File

PanDDA analysis group deposition of ground-state model of SARS-CoV-2 main protease screened against DSI poised (Enamine), Fraglites and Peplites (Newcastle university), Mini Frags (Astex), York 3D (York university), electrophile cysteine covalent (Weizman institute) fragment libraries

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

To be published

Released	2020-04-01
Method	X-RAY DIFFRACTION 1.27 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS

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5RE4 \| pdb_00005re4	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z1129283193

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.88 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, SZY

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5RE5 \| pdb_00005re5	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z33545544

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 2.07 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, T0J

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5RE6 \| pdb_00005re6	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z54571979

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.87 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, O0S

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5RE7 \| pdb_00005re7	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z30932204

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.79 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, T0S

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5RE8 \| pdb_00005re8	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z2737076969

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.81 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, T0V

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5RE9 \| pdb_00005re9	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z2856434836

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.72 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, LPZ

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5REA \| pdb_00005rea	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z31432226

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.63 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, JGP

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5REB \| pdb_00005reb	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z2856434899

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.68 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, T0Y

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5REC \| pdb_00005rec	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z1587220559

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.73 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, T1J

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5RED \| pdb_00005red	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z2856434865

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.47 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, JJG

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5REE \| pdb_00005ree	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z2217052426

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.77 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, T1M

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5REF \| pdb_00005ref	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z24758179

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.61 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	6SU, DMS

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5REG \| pdb_00005reg	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z1545313172

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.67 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, LWA

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5REH \| pdb_00005reh	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z111507846

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.8 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	AWP, DMS

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5REI \| pdb_00005rei	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z2856434856

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.82 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, T1S

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5REJ \| pdb_00005rej	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with PCM-0102241

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.72 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, T1V

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5REK \| pdb_00005rek	Download File View File

PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with PCM-0102327

Fearon, D., Owen, C.D., Douangamath, A., Lukacik, P., Powell, A.J., Strain-Damerell, C.M., Resnick, E., Krojer, T., Gehrtz, P., Wild, C., Aimon, A., Brandao-Neto, J., Carbery, A., Dunnett, L., Skyner, R., Snee, M., London, N., Walsh, M.A., von Delft, F.

(2020) Nat Commun 11: 5047-5047

Released	2020-03-25
Method	X-RAY DIFFRACTION 1.74 Å
Organisms	Severe acute respiratory syndrome coronavirus 2
Macromolecule	3C-like proteinase (protein)
Unique Ligands	DMS, T1Y

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Structure Determination Methodology

Scientific Name of Source Organism

Taxonomy

Experimental Method

Polymer Entity Type

Refinement Resolution (Å)

Release Date

Enzyme Classification Name

Membrane Protein Annotation

Symmetry Type

SCOP Classification

5R7Y | pdb_00005r7y

5R7Z | pdb_00005r7z

5R80 | pdb_00005r80

5R81 | pdb_00005r81

5R82 | pdb_00005r82

5R83 | pdb_00005r83

5R84 | pdb_00005r84

5R8T | pdb_00005r8t

5RE4 | pdb_00005re4

5RE5 | pdb_00005re5

5RE6 | pdb_00005re6

5RE7 | pdb_00005re7

5RE8 | pdb_00005re8

5RE9 | pdb_00005re9

5REA | pdb_00005rea

5REB | pdb_00005reb

5REC | pdb_00005rec

5RED | pdb_00005red

5REE | pdb_00005ree

5REF | pdb_00005ref

5REG | pdb_00005reg

5REH | pdb_00005reh

5REI | pdb_00005rei

5REJ | pdb_00005rej

5REK | pdb_00005rek